haplotype 中文意思是什麼

haplotype 解釋
單倍體型
  1. Even the difference of a single genetic marker delineates a distinct haplotype

    區別一唯一基因標志描述一分明haplotype 。
  2. Haplotype is a person s individual footprint of all tested genetic markers

    Haplotype是人的單獨腳印所有被測試的基因標記。
  3. Y chromosome is transmitted in the form of hap - loid, leading to extreme disequilibrium of y chromosome genetic markers distribution in different population. the prerequisite of str application in forensic medicine is establishment of a database of population y - str loci haplotype distribution. therefore we need to form haplotypes by using the known highly polymorphic str loci and detect more local population

    由於y染色體呈單倍體遺傳，導致y染色體遺傳標記在不同人群中的分佈極不平衡，群體差異比常染色體str位點更加顯著，在法醫學應用的前提條件是：建立含有多個y - str位點的單倍型的群體分佈數據庫。
  4. The value of discrimination power and the exclusion chance of paternity for these y - str loci are same as the value of haplotype diversity

    單倍型變異度為0 . 9991 ，其個人識別能力和非父排除率也為0 . 9991 。
  5. The goal of the project is to develop a ( haplotype ) map of the human genome, whereby its pattern of common dna sequence variations can be deciphered

    該國際人類基因單型圖譜研究的目標，乃發展人類基因（單形）圖譜，以譯解基因排列變異的普遍模式。
  6. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  7. Besides, the centre actively seeks opportunities for the development of multi - disciplinary programmes to combine cutting edge research in molecular and cell biology, biochemistry, chemical biology, bioinformatics and clinical medicine, using advanced and high throughput genomic technologies. the centre is a participant of the international haplotype mapping project

    此外，中心亦積極尋求發展跨學科研究的機會，藉著先進及高通量的基因技術，結合在分子及細胞生物學、生物化學、化學生物學、生物資訊學及臨床醫學方面的尖端研究。
  8. Some issues were discussed in the review, which include defining and controlling of confounding effects, selection of candidate genes and single nucleotide polymorphisms ( snps ), application of intermediate phenotype and haplotype analyses as well as judgement of the result in association studies

    文中就關聯研究中混雜的識別與控制、候選基因的選擇、中間表型的應用、單體型分析方法的應用，以及結果的判定等問題進行了討論。
  9. The analysis of variation in han group revealed geographic difference. the genetic distances based on the sequence of mtdna haplotype have been obtained and the phylogenetic trees were constructed

    在測定的無關個體mtdna單倍型序列的基礎上做進化距離分析，並構建了各民族內部和民族間的系統發育樹。
  10. And the haplotype that includes the mutated gene will likewise get whittled down with each subsequent recombination

    每一次染色體重組，包含了突變基因的單純型也會越來越短。
  11. The advanced study institute, titled " statistical genetics : from haplotype maps to disease susceptibility genes ", will explore how the recently completed haplotype map can be used to find genes that affect the risk to common diseases

    資深科研團的主題為由人類基因組單體型圖至疾病易感性基因之統計遺傳分析，會上將探討如何用新近完成的人類基因組單體型圖，以辨別可影響致病風險的基因。
  12. Haplotype frequency date of 37 different types were obtained. allele frequency comparisons with other han population samples analyzed for the markers of dys390 and dys391 showed a substantial similarity

    對這3個基l天1座構成的單倍型進行觀察， 163例共檢測到37種單倍型，單倍型多樣性為0 . 9485 。
  13. The abstract of the article entitled " a haplotype map of the human genome ", by the international hapmap consortium, to be published in the 27 october issue of nature magazine

    國際hapmap協作組將於10月27日出版的《自然》科學雜志發表題為人類基因組單體型圖的文章摘要：
  14. ( 2 ) gene structure of the rh d - negative in chinese have polymorphism, especially in the individuals with c antigen, which accorded with the oriental character. d gene exon of chinese polymorphism expressed for intact, partial deletion and total deletion, and probably existed specific d ( nf ) ce haplotype

    中國人rhd基因結構具有多態性，特別是帶有c的個體，符合東方人具有完全缺失、部分缺失和不缺失三種情況，並可能存在特殊的d （ nf ） ce單體型。
  15. Nested clade analysis ( nca ) generated almost identical results, supporting to treat these populations as different management units. no shared haplotype was found among china mainland, northern japan, and southern japan populations, and 25 fixed diagnostic sites differences separate the three populations

    巢式進化支分析nca （ nestedcladeanalysis ， nca ）的結果與amova基本一致，均支持把分佈於東北、華南和四川的梅花鹿種群歸入各自獨立的管理單元（ managementunit ， mu ） 。
  16. A haplotype map of the human genome

    人類基因組單體型圖
  17. In each sample, different loci were united to form y - str haplotype

    同一樣品的各y str位點型別聯合，構建y str單倍型。
  18. The full name of the hapmap project is the " international haplotype map project "

    Hapmap計劃全名為人類基因組單體型圖國際計劃。
  19. Appropriate application of intermediate phenotype of diseases and haplotype analyses may increase the opportunity to obtain meaningful findings in association studies

    適當的應用中間表型和單體型分析方法可以增加關聯研究有意義發現的機會。
  20. Distribution of different haplotype systems in population and their significance in the application of forensic medicine were statistically analyzed

    統計分析各y str位點及單倍型的群體分佈特徵，獲得其頻率的群體分佈數據，並討論其法醫學意義。
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