heavy chain h chain 中文意思是什麼
heavy chain h chain
解釋
重鏈-
Thus, immunologists have sought smaller molecules with the antigen - recognition capability of antibodies. the variable domains of the heavy ( h ) and light ( l ) chains are sufficient for antigen recognition but the non - covalent complex of the two variable domains ( fv ) is unstable. it is possible to genetically engineer a single - chain fv ( scfv ) with the h chain v region connected to the l chain v region via a 15 amino acid linker composed of serine and glycine amino acid residues
二、日本血吸蟲單克隆杭獨特型抗體np30的單鏈狐（ scf ）的構建、表達及對balbic小鼠誘導保護性作用研究l 、日本血吸蟲單克隆杭獨特型抗體np0的單鏈抗體歸cfv ）的構建、表達通過pcr方法體外擴增並經測序驗證的重鏈、輕鏈可變區（ vh 、 vl ）基因先後重組入原核表達質粒ptha90相應的位點上，中間通過一連接肽（ gly在er ） 。 -
Objective the origin and the nature of the hodgkin and reed - sternberg ( h / rs ) cell of hodgkin ' s lymphoma ( hl ) has been attracting a lot of medical researchers engaged in studying it, for its character by scattered large atypical cells residing in a complex admixture of inflammatory cells. great improvement has been made since a new method of isolation of single h / rs cells from a frozen section had been set up by kuppers in 1994, and many studies have approved of the b - cell derivation of h / rs cell. lt has been reported that h / r - s cells might partly be originated from b - cell in our research before, but at the same time, we also found that only 18. 8 % of h / rs cells express cd20, 31. 3 % of immunoglobulin heavy chain ( igh ) rearrangement have been revealed
目的霍奇金淋巴瘤（ hodgkin ' slymphoma ， hl ）由於它的惡性腫瘤細胞? h rs細胞一般只佔腫瘤組織的極少部分（不到1 ） ，且散在分佈在背景細胞間，因此對于h rs細胞的來源和性質研究一直是人們探索的目標。 1994年德國科隆大學k ppers等發展了一種從冰凍組織切片上用顯微操作儀挑取單個h rs細胞的顯微切割方法進行h rs細胞基因分析后，人們對h rs細胞來源的研究有了突破性的進展，多數支持b細胞來源。我們的前期研究也支持部分h rs細胞為b細胞來源，但我們發現只有18 . 8的h rs細胞表達cd20 ， 31 . 3的hl檢測到igh基因重排克隆性條帶。
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