histone 中文意思是什麼

histone 解釋
n. 名詞 【生物化學】組蛋白。

  1. Camp, pka inhibitor peptide ( pki ), kemptide, histone h1 ( type iii - s ), polyvinyl alcohol, na3vo4, naf, b - glycerophosphate, p - nitrophenylphosphate, 3 - [ n - morpholino ] - propanesulfonic acid ( mops ), genistein, ml - 9, leupeptin, aprotonin, pepstatin, chymostatin, trypsin - chymotrypsin inhibitor were purchased from sigma chemical co. [ r - 32 p ] atp was obtained from yahui biomedical enginnering co

    實驗材料昆明系小白鼠，中國醫科大學實驗動物部提供。測活用試劑除nacl山inni為國產分析純對rr為amesa產品， y乍jatp為北京亞輝生物醫學工程公司產品外，余者均為sipoa產品。
  2. It is the result of interaction between dna and histone proteins

    這是dna分子與組蛋白相互作用的結果。
  3. At last, we propose a new model to interpret the process of dna wrapping around histone

    並且，我們提出了組蛋白旋轉模型來解釋dna纏繞到組蛋白八聚體上去的方式。
  4. Arginine an amino acid found especially in the histone proteins that surround dna in chromosomes

    精氨酸：在染色體中與dna非特異性結合的組蛋白中發現的一種氨基酸。
  5. Dynamic distribution of ser - 10 phosphorylated histone h3 and microtubules in wheat root cells during the mitosis

    3和微管蛋白在小麥根尖細胞有絲分裂過程中的動態分佈
  6. Dna has negative charges and histone has positive ones. so the interaction between them is coulombic force

    Dna分子帶強負電而組蛋白則帶正電，庫侖相互作用起主要的作用。
  7. In eukaryotic cells, dna is located in nucleolus in the form of chromatin by combining with histone proteins

    在真核生物中， dna分子纏繞在組蛋白上形成染色質保存在細胞的細胞核中。
  8. These issues are essential to the understanding of the nature of cell cycle control, and to elucidating the roles of the histone acetylation modification in cell cycle regulation in eukaryotes. in this thesis, we studied the mechanisms of histone acetylation in cell cycle regulation in physarum polycephalum, a naturally synchronized slime mold. the results of this study confirmed that histone acetylation changed the expression of proteins related with the regulation of checkpoint conversion in cell cycle

    初步確定了組蛋白乙酰化在多頭絨泡菌細胞周期各轉換點的調控過程中對細胞周期調控相關蛋白表達水平的調節作用；了解了組蛋白乙酰化修飾對細胞周期各轉換點調控的作用途徑；建立了組蛋白乙酰化修飾對多頭絨泡菌細胞周期調控機制的基本模型。
  9. In prokaryotes the nuclear material is simply a circular strand of dna, not complexed with histone proteins, and cell division is amitotic

    在原核生物中，核物質僅是一個簡單的環狀dna ，而不與組蛋白結合，並且細胞為無絲分裂。
  10. The rnapii - associated complex elongator has histone acetyltransferase ( hat ) activity and thus might fulfil such a role

    與磷酸化的rnap結合的elongator復合物具有組蛋白乙酰轉移酶（ hat ）活性，它可能執行這一功能。
  11. 5, histone acetyltransferase gene ygcns and histone deacetylase gene yrpd3 were cloned and expressed, which has laid down a foundation for studying chromosome remodeling in vitro

    5 ，我們克隆並純化了酵母中的組蛋白乙酞基轉移酶基因gcns和去乙酞化酶基因rpd3 。
  12. 6, we used gcn5 and rpd3 genes as probes to detect the homologous sequences in drosophila melanogaster by fluorescence in situ hybridization ( fish ). this work has provided useful information for the localization and cloning of related histone acetyltransferase and histone deacetylase genes in drosophila melanogaster

    6 ，利用己獲得的酵母gcns和rpd3基因為探針，對果蠅多線染色體進行原位雜交實驗，試圖找出與gcns和rpd3基因同源的基因片段。為今後克隆和分離果蠅中與乙酞化和去乙酚化相關的基因奠定基礎。
  13. Histon acetylation plays an important role in regulation chromatin structure and transcriptional activity. however, there is a lit tle investigation in cloned cattle about histone acetylation. andmore, in many dead cloned cattle, the lung abnormality is mostly obvious

    在報道的克隆牛發育異常中，肺臟的異常比較普遍和明顯，而在我們的克隆牛工作中也發現了類似問題，所以我們選用克隆牛肺臟組織作為實驗材料，進行組蛋白乙酰化研究。
  14. Epigenetic modification of the genome ensures proper gene activation during development and involves : genome methylation changes ; the assembly of histon and histone variants into nucleosomes and remodeling of other chromatin - associated proteins such as linker histones, polycomb group, nuclear scaffold protein, and transcription factors

    這些染色質的再程序化包括dna的甲基化和核小體組蛋白的乙酰化等。組蛋白乙酰化在染色質結構調節、 dna復制、基因轉錄、細胞分化及癌細胞發育都有研究，但在克隆動物中卻是一個有待深入探索的領域。
  15. We get to the conclusions : ( 1 ) the histon acetylation level has some derease in the lung of cloned cattle ; ( 2 ) in the cloned cattle xiaobai, the histone acetylation level is lower than that in normal control, however, higher or adjacent to that in other dead cloned cattle ; ( 3 ) there is no significant difference during those cattle from the cumulus, fetal fibroblast and adult fibroblast cell donor

    我們發現： （ 1 ）在克隆牛中組蛋白乙酰化水平基本上都有所降低； （ 2 ）克隆牛xiaobai乙酰化水平比正常牛低，而基本上是高於或接近死亡克隆牛水平的； （ 3 ）在我們所研究的三個供體細胞系（卵丘細胞，成體成纖維細胞和胎兒成纖維細胞）中，乙酰化水平無明顯差異。
  16. Based on the data arising from the experiments in this thesis, a hypothesized model, which intends to explain the mechanisms and relationship between histone acetylation and the expression of important cell cycle regulating factors in physarum polycephalum. the main results and conclusions of this thesis are as follows. 1

    通過1 」 sa處理、 rt干cr和蛋白兔疫印跡實驗，發現多頭絨泡菌細胞中存在著哺乳動物細胞周期調控相關回于的同源物，包括細胞周期素類cyclinbi蛋白、癌基因產物類c foo和類c j 。
  17. By treating the cells in s, g2 phase and prophase with histone deacetylase inhibitor tsa, and through the application of microscopic observation and western - blotting, we demonstrated that histone acetylation modification played important roles in the cell cycle regulation in physarum polycephalum, affecting the normal crossover of the checkpoints of s / g2, g2 / m and mitosis exit

    這些炎白的表達水平具有細胞周期依賴性，隨著細胞周期的進行而發生變化。 tsa處理引起的多頭絨泡菌s期、 gz期和前期細胞內組蛋白h3乙酚化水平的提高，改變了細胞內類cyclinbi蛋白、類。
  18. 4. histone hi kinase assay ; three eggs were removed from m16 medium, washed in collection buffer and transferred to a 0

    酶活性測定的鼠卵收集：根據實驗需要每隔30min從培養基中取出3個受精卵，收集液中清洗，移人0
  19. We do not know what cell cycle - associated proteins are regulated by histone acetylation modification, especially at the checkpoints of g1 / s, s / g2, g2 / m and mitosis exit. neither do we know about the manner in which histone acetylation regulates the expression of these genes

    在真核細胞周期調控的重要檢驗點g1 / s和g2 / m ，以及其他的轉換點s / g2和走出m期的各個過程中，哪些細胞周期調控相關蛋白的表達活性與細胞內的組蛋白乙酰化水平相關
  20. However, it is difficult to relate the histone acetylation level with the gene expression level. we indicate, although histone acetylation acts to enhance the access of transcription - associated protein to dna, the activation of gene expression only need containing some acetylation level, but the hyperacetylation and underacetylation would effect the gene expression, so as to the abnormal development

    而在克隆牛中組蛋白乙酰化水平雖然有所降低，但如果這種降低仍然為基因的表達提供了足夠的基礎，這就對基因的正常表達造不成很大影響；但如果組蛋白乙酰化水平過高或過低，可能要影響到其他因子的作用，從而影響了基因表達的調節，最終導致生物個體發育異常。
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