intron a 中文意思是什麼

intron a 解釋
甘樂能,干擾能<抗簿藥,抗腫瘤藥>
  • intron : 插入序列
  • a : an 用在以母音音素開始的詞前〉 indefinite art 1 〈普通可數名詞第一次提到時，冠以不定冠詞主要表示類...
  1. The length of this phytase gene is1506bp interrupted once by an intron of 102bp in the 5 " part of the gene, this intron contains donor sequence - gtatgc, lariat sequence - gctgac and acceptor sequence - cag which are typically conserved sequence of the intron of fungal phytase gene. this gene encodes a peptide of 467amino acid residues with molecular weight of 51. 37kda, containing 13 potential n - glycosylation sites and a signal peptide sequence made up of 19 amino acid residues at n teminal of the peptide

    核苷酸序列分析表明， pcr擴增產物中包含有完整的phya基因，該基因全長1506bp ，其中包含一段長102bp的內含子，該內含子具有真菌植酸酶基因內含子的特徵保守序列： donor序列? gtatgc ， lariat序列? gctgac及acceptor序列? cag 。該基因編碼467個氨基酸，理論分子量為51 . 37kda ，其上有13個潛在的n -糖基化位點， n端19個氨基酸為信號肽序列，植酸酶活性位點序列（ crvtfaqvlsrhgaryptdskgk ）位於氨基酸序列的+ 71 + 93 。
  2. Based on cdna sequences of ( 3 - carotene ketolase ( cr / ff ) and p - carotene hydroxylase ( c / - fz ), a 1. 6 kb crtw genomic sequence with six introns, and a 3kb crtz genomic sequence with five introns were clone, respectively. all the exon - intron junctions conform closely to gu - ag consensus splicing rule

    本論文工作成功地克隆兩個關鍵酶基因的基因組序列，發現crtw和crtz分別包括6個和5個內含子序列，所有這11個內含子的剪切位點都符合gu - ag規律。
  3. Intron a noncoding dna sequence that occurs between coding sequences ( exons ) in many eukaryote genes

    內含子：是大多數真核生物基因中位於編碼序列（外顯子）之間的不編碼的dna序列。
  4. And the intron had a lot of gt repeated sequence. the dna and protein sequence of this gene was analyzed using the bioinformatics tools. two functional domains were found in the protein

    運用生物信息學手段對3一磷酸甘油脫氫酶基因核酸以及蛋白質序列做出了分析，發現這個基因編碼兩種功能的結構域，磷酸化酶結構域和3一磷酸甘油脫氫酶結構域。
  5. Compared with bombyx. mori, the exon regions of alpha - amylase gene of bombyx mandarina have 13 transitions, 4 transversions and a 12bp insertions, while the intron regions have 362 transitions, 343 transversions, a 94bp insertions and a 56bp deletions. the whole alpha - amylase gene ( including the 5 ' - and 3 ' - utrs ) of bombyx mandarina has 380 transitions, 350 transversions, 113bp insertions and 57bp deletions

    野桑蠶相對於家蠶來說，在-澱粉酶基因外顯子區域發生了13次轉換、 4次顛換、 12bp插入，在內含子區域發生了362次轉換、 343次顛換、 94bp插入和56bp缺失，全基因（包括utr ）共發生mmrttoopmi mgzx ffatt了380次轉換、 350顛換、 113hp插人和57hp缺失。
  6. A pair of primers was designed based on the conserved regions of other higher plants " epsp synthase through homology alignments. two dna fragments were first cloned from o. violaceus by performing prc which used o. violaceus genome as the template. one has 798 nucleotides and the other 1157 nucleotides, but they can encode the same amino acid sequence and have same extrons according to the gt - ag rule of characteristic sequence of enkaryoutic intron

    根據同源比較其它高等植物中epsp合成酶基因，找出該基因的保守序列並設計一對寡核苷酸引物，以諸葛菜的總dna為模板進行pcr反應，克隆出了兩個epsps基因的片段，其中一條長為797bp ，另一條1157bp ，它們在genbank的登錄號為： af440390 、 af440391 。
  7. The sequences of intron, however, had only 74 % of homology with those of a. thaliana ban. in addition, amino acid sequence of oilseed rape ban had 78 % of homology and 87 % of similarity with those of a. thaliana and had various homologies ( 55 - 64 % ) with many nadph - dependent reductases of other plants

    將甘藍型油菜ban氨基酸序列進行同源比較，發現甘藍型油菜ban片段的181個氨基酸與擬南芥有78的氨基酸序列相同，相似性達87 ；與80多種植物的nadph還原酶類也有不同程度的同源性（ 55 - 64 ） 。
  8. This vector, including sbe2b gene, was 6. 06kb long, containing endosperm specific promoter and a intron that enhanced the transcript efficiency. both sense and antisense cdna were transformed to upregulate and downregulate amylose content and relative branching characters

    正向連接的表達載體用於增加胚乳中支鏈澱粉的含量，反向連接用於減少胚乳中支鏈澱粉的含量，增加直鏈澱粉的含量。
  9. This expression vector plbcas - hsa - lgl has the following advantages : i ) the 1. 7kb promoter is able to drive cell - specific and hormone - dependent expression ; ii ) the inclusion of intron - 1 can increase expression level of fusion genes ; iii ) the 5 ' utr of bovine p - casein mrna may have a positive role in both transcriptional and post - transcriptional regulation ; iv ) the gfp gene make the selection of positive clone among embryos possible ; v ) the gfp gene can be easily excised via cre - mediated recombination between the two loxp sites after the expression vector has been integrated into chromosome ; vi ) the two incompatible lox sites, loxp and lox2272, would facilitate cre - recombinase mediated cassette exchange ( rmce ), which in theory will leading to develop a technology of site - specific gene expression in animal mammary glands

    該載體的特點是：具有可以調控外源基因在乳腺中特異表達的牛-酪蛋白基因5 `端側翼區和包括第一外顯子及內含子在內的5 `端調控區；將人血清白蛋白cdna準確地置於牛-酪蛋白基因第二外顯子中的翻譯起始密碼子atg之後，而且沒有增加額外的序列和使人血清白蛋白cdna移碼；引入標記基因gfp ，便於在胚胎期鑒定陽性胚胎，減少受體；引入cre lox重組系統： （ ? ）標記基因gfp的兩端的兩個loxp位點可以在表達載體整合到基因組后，刪除標記基因； （ ? ）餘下的一個loxp位點可以和前面的lox2272位點組成cre重組酶介導的盒式交換系統。
  10. Then, 5. 5kb thrombiotin gene was amplified with the same technique from the genome of a baby ' s blood, which included the begining part of intronl to the teminator. in addition, 6. 0kb and 1. 8kb homlogous arms were also amplified from a cow with high yield. the 6. 0kb homologous arm contains the promotor, extron 1, extron2, extron3 and intron 1, intron2 and part of the intron3 fragment, while the 1. 8kb homologous right arms contains exon13, exon14 and part of intron 13, the whole intron14 and part intron 14 of asl - casein gene of bovine

    通過長片段pcr從高產奶牛的基因組中獲得了打靶所需的長、短同源臂序列，長度分別為6 . 0kb和1 . 8kb ，位於s1 -酪蛋白基因的5上游區到第三內含子和十二到十四內含子；從綿羊全血基因組克隆得到了綿羊的-酪蛋白基因啟動子區到第二內含子區4 . 1kb的5調控序列；利用同對引物克隆得到了水牛的同基因序列；從廣西當地一嬰兒臍血基因組中通過獲得了人血小板生成素基因，位於第1內含子到終止子後部分的序列，長達5 . 5kb 。
  11. In the present study, a portion ( the big intron between exon 5 and 6, ca. 2 kb ) of glycerol - 3 - phosphate acyltransferase ( gpat ) gene of 15 wild tree peony accessions collected from 15 populations were analyzed using pcr - rflp technique and 9 accessions representing all of 8 species in sect. moutan were sequenced

    本文對采自15個野生居群，代表牡丹組全部8個野生種的15份材料的gpat基因片段（外顯子5和6之間的內含子）進行了pcr - rflp分析，並對代表牡丹組全部8個野生種的9份材料進行了測序。
  12. To isolate hfl -, hf2 gene encoding flavonoid - 3 ', 5 ' - hydroxylase ( f3 ', 5 ' h ) from petunia hybrida of the purple flower, we used a polymerase chain reaction ( pcr ) amplification using the genomic dna as a template. the result indicated that the hfl dna was 2797bp in total length and encoded 506 amino - acid, containing three extron and two intron ; hf2 dna was 2223bp in total length and encoded 509 amino - acid, containing three extron and two intron. comparison of the sequence with genbank databases revealed that hfl dna and hf2 dna shared significant nucleotides identity ( 98. 97 % and 99. 04 % respectively ) and amino - acid identity ( 99. 41 % and 99. 41 % respectively )

    Hf1dna全長2797bp ，包括3個外顯子， 2個內含子，其中一個開放閱讀框架（ orf ）編碼506個氨基酸，與文獻報道的序列相比較，具有98 . 97核苷酸同源性與99 . 41氨基酸同源性： hf2dna全長2223bp ，包括3個外顯子， 2個內含子，其中一個開放閱讀框架（ orf ）編碼509個氨基酸，與文獻報道的核苷酸同源率為99 . 04以及氨基酸同源率為99 . 41 。
  13. There is an entire non - ltr retrotransposon in intron ii, which encodes a reverse transcriptase ; also a segment in intron ii is highly homologous with another retrotransposon

    在intron中有一個完整的non - ltrretrotransposon ，其內編碼一個reversetranscriptase ； intron還有一段序列與另外一種反轉座子的部分序列高度同源。
  14. In the alpha - amylase gene, the length of the non - ltr retrotransposon, located in intron ii, is equal in bombyx mori and bombyx mandarina, with a nucleotide sequence similarity of 98 % ; the length of the coded reverse transcriptase is equal in both nucleotide and amino acid sequence with a similarity of 98 % also

    家蠶、野桑蠶-澱粉酶基因intron中的（野桑蠶） non - ltrretrotransposon之間序列長度相等，相似性為98 ，其內編碼reversetranscriptase的基因，序列長度相等，核苷酸序列和氨基酸序列相似性達98 。
  15. So, as well as spelling out which amino acids are needed to produce a specific protein, the part of the exon immediately next to the intron contains information that is essential for the gene editing process

    因此，我們除了要弄清楚哪些氨基酸是產生某一特定蛋白所必需的外，還要弄清楚緊靠內含子的外含子里哪一部分含有基因編輯過程所必需的信息。
  16. A new method for the splicing - site recognition of rice dna sequences was designed. based on the gt - ag intron organization principal, support vector machines ( svm ) was used to predict the splicing sites. through machine learning, a model was built on some test data set of true and pseudo splicing sites

    根據真核生物內含子在剪切位點前後存在保守堿基的特徵，用支持向量機技術構建分類器模型，有效地在基因組序列中識別剪接位點， 3位點識別的準確度87 . 96 ，在5位點識別的準確度達85 . 41 。
  17. In 2001, wilson and his colleagues cloned another two members - human wnk1 gene and wnk4 gene which were located on chromosome 12 and 17, respectively. the two genes are disease - causing genes responsible for a mendelian hypertension. the disease - causing mutations are the large deletions in the first intron in wnk1 gene, causing increased expression in leukocytes

    2001年， wilson等克隆了此家族的另兩個成員? ?人的wnk1和wnk4基因，分別位於12號和17號染色體，這兩個基因是一種孟德爾遺傳型高血壓病的致病基因，致病突變分別是wnk1基因第一內含子的大片段缺失，導致患者白細胞的基因表達量提高5倍左右。
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