isoform 中文意思是什麼

isoform 解釋
對碘氧基苯甲醚
  1. Polymer his - tagged peac1 - gfp efficiently activated myosin mg - atpase activity, which indicated that peacl might take part in correlative living activities in vivo. moreover, this result provided experimental proof in vitro for fusing gfp to actin isoform directly to study the dynamics of microfilaments and its regulation in vivo. we prepared rabbit anti - pea actins polyclonal antibodies using peacl as antigen which being expressed and purified from prokaryotic cells, and the antibodies possessed better immunity activity to pea actins

    通過肌動蛋白體外對dnase以及肌球蛋白atpase活性影響的研究,發現單體his - taggedpeac1 - gfp能顯著抑制dnase活性,在肌動蛋白聚合條件下能有效激活肌球蛋白atpase活性,這一結果預示著peac1在體內可能參與相關的生命活動,為利用gfp直接與肌動蛋白異型體融合來研究體內微絲的動態變化及其調節提供了實驗依據。
  2. We have identified p120ctn expression in cultured hepatocyte and liver tissues using rt - pcr, immunohistochemistry and immunofluorescence microscopy, p120ctn isoform 1a and 3 a expression have been detected in the cells and tissues

    而當過度表達p120ctn后,細胞粘附能力有所增加,遷移能力降低,並且過度表達的pl加ctn主要分佈於膜下,其次是胞漿。
  3. An unusual rice calmodulin isoform, oscam61, was first obtained in our lab, which contains an n - terminal cam domain and a c - terminal basic extension with a potential prenylation site. in vitro activity assays confirm oscam61 as a functional calmodulin. using the green fluorescent protein ( gfp ) as a visual marker, we further studied subcellular localization of oscam61 in stably transformed tobacco cells

    利用綠色熒光蛋白( greenfluorescentprotein , gfp )作為標記,研究了oscam61在煙草細胞中的定位, gfp - oscam61融合蛋白(具有開放的異戊烯化修飾位點)定位於細胞質膜和細胞器膜上,而oscam61 - gfp (異戊烯化修飾位點被gfp封閉)定位於細胞核的核質中。
  4. It may have a preventional function from alzheimer ' s disease. molecular biological studies are shown that apoe isoform has a isoform - specific role to neurodegeneration. apoe3 and apoei aid to sustain the stabilization of cytoskeleton protein tau, while apoe4hyperphosphorylates tau to destabilize the microtubule protein, which will make neurocyte easy to form neurofibrillary tangles in ad

    分子生物學研究發現, apoe異構體對神經細胞退化表現出異構體特異作用, apoe _ 3和apoe _ 2有助於維持微管的穩定性,而apoe _ 4則使tau蛋白超磷酸化,破壞微管的穩定性,使神經細胞易於形成神經纖維纏結。
  5. In other studies of mutant ( knockout ) mice that fail to express the neuronal isoform of nitric oxide synthase ( nos ), smaller infarcts develop and the mice have less severe neurologic deficits than normal mice ( 61 )

    其他一些研究變異(被擊昏的)老鼠的試驗沒有能夠表達一氧化氮合酶( nos )的神經元對碘氧基苯甲醚,但是出現的梗死梗小,而且與正常的老鼠相比,老鼠的神經學缺陷也不那麼嚴重( 61 ) 。
  6. The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion

    Nyd - sp27內源性表達在人體的胰腺導管上皮細胞,並在囊性纖維化時表達增高,顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達,可以糾正缺陷的胰腺陰離子分泌。
  7. In order to understand the apoplast cam gene and the relationship between the apoplast cam and cam isoforms, we intended to get transgenic plants harboring soybean calmodulin isoform genes ( scams ) fused to gfp as a reporter and study the subcellular localization of scams

    為了進一步利用分子生物學方法在基因水平上研究胞外cam的存在,同時研究胞外cam與cam亞型之間的關系,本論文利用綠色熒光蛋白( gfp )作為報告基因研究了大豆cam基因家族( scams )的亞細胞定位。
  8. In cells, apx has several isoenzymes, cytosolic and chloroplastic isoforms are main ones, of which the chloroplastic isoform represents a large portion of apx of the cell

    它在細胞內有多種同工酶,主要分為細胞質型和葉綠體型,其中,葉綠體型在細胞中佔有很大的比重。
  9. By gene fusion and prokaryotic expression, we purified a pea actin isoform ( peac1 ), his - tagged peac1, his - tagged gfp and his - tagged peac1 - gfp from inclusion body. after filtrating a series of induction condition, we expressed and purified his - tagged peac1 with soluble form in a large amount

    利用基因融合技術,原核表達並從包涵體中純化了豌豆肌動蛋白異型體peac1 、 his - taggedpeac1 、 his - taggedgfp以及his - taggedpeac1 - gfp ,並通過誘導條件的篩選達到了可溶性表達與大量純化his - taggedpeac1 - gfp的目的。
  10. Construction and expression of a new human growth hormone isoform - gst fusion protein

    人新的生長激素異形體基因的克隆及其在大腸桿菌中的表達
  11. Physicochemical determinations may include isoform, electrophoretic, and liquid chromatographic patterns, as well as spectroscopic profiles

    物理化學性質包括異構體,電泳和液相色譜行為及光譜性質等。
  12. The yeast two - hybrid system was established. in yeast two - hybrid system, mt - 3 interacts with mt - 3. a further two - hybrid test also indicated that mt - 3 weakly interacted with its isoform mt - 1. these primary results suggest that mt - 3 probably trend to homodimerize or heterodimerize in vivo

    結果表明: mt - 3與mt - 3之間在酵母細胞內能發生相互作用,進一步用酵母雙雜交實驗還表明mt - 3與mt - 1間也存在弱相互作用。
  13. Then we cloned the mature ca fragment and the same region of the selected ca fragment from library plasmid to vector pgadt7, but neither did they interact with ga in the assay of two - hybrid system. then we used arabidopsis cam2 isoform as bait to screen the two - hybrid library

    之後將成熟ca和文庫中篩到的ca編碼部分的基因分別亞克隆至雙雜交激活域載體pgadt7 ,進行雙雜交檢測它們與g蛋白的相互作用,結果仍為陰性。
  14. It has been demonstrated that kvl. 2, an isoform of delayed - rectifier potassium channel, is up - regulated in the ischemic neurons. besides, the activity of kvl. 2 is tyrosine phosphorylation dependent, phosphorylation of the tyrosine residue in the amino terminus of the channel by tyrosine kinases suppresses the channel current. therefore, we hypothesize that vegf could enhance the phosphorylation of kvl. 2, which results in an inhibition of / k

    在介導i _ k的鉀通道家族中, kv1 . 2是其中的一個亞型,研究報道它在缺血神經元中的表達是增高的;此外,它的活性與其酪氨酸磷酸化水平相關,在其氨基末端的酪氨酸殘基經酪氨酸激酶磷酸化后可顯著降低其介導的電流的幅度。
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