leucine-rich repeat 中文意思是什麼
leucine-rich repeat
解釋
富含亮氨酸的重復單位-
Not all adaptive immune systems use the immunoglobulin fold as the basis for specific recognition molecules : sea lampreys, for example, have evolved an adaptive immune system that is based on leucine - rich repeat proteins
並不是所有的獲得性免疫系統都是利用免疫球蛋白來特異的識別外來分子，例如七鰓鰻，它利用的是一種富亮氨酸的蛋白。 -
Nogo - 66 receptor, ngr, cloned in 2001, is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth. both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains. northern blot, in situ hybridization, western blot and immunocytochemistry analyses show that in addition to oligodendrocytes, nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord, nogo - a is also found in peripheral organs such as heart and testis
Northernblot 、原位雜交、 westernblot和免疫組化結果證明： nogo amrna和nogo蛋白除了在cns的寡突膠質細胞中表達，還表達于發育階段和成年的腦、脊髓和外周神經節的某些神經元中，在外周組織如睪丸和心臟也有表達； nogoe在cns和pns以及多種外周組織中有廣泛分佈； nogo （除表達于腦和心臟外，在骨骼肌中有較高表達。
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