lymphocyte differentiation 中文意思是什麼
lymphocyte differentiation
解釋
淋巴細胞分化- lymphocyte : n. 【醫學】淋巴細胞，淋巴球。lymphocytic adj.
- differentiation : n. 1. 差別，區別；區分，劃分。2. 【生物學】分化，變異。3. 【地質學；地理學】（從共同的巖漿產生出不同的巖石的）分異作用。4. 【數學】微分法。
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The b lymphocyte stim lator ( blys ) also known as baff, tall - 1, thank, ztnf4, is the most recent addition to the tumor necrosis factor family ( tnf ) ligands. blys induces both in vivo and in vitro b cell proliferation, differentiation and immunoglob lin secretion. meanwhile, it also strongly suppresses the growth of tumor cell lines. the over - production of blys is associated with the development of certain autoimmune disease, such as systemic lupus erythaematosus ( sle ), rheumatoid arthritis, myasthenia gravis, sj greh ' s syndrome
人b淋巴細胞刺激因子（ hblys ）是1999年發現的腫瘤壞死因子超家族成員。最早發現其可誘導腫瘤細胞凋亡，之後發現它是一個強有力的b細胞共刺激因子，它在體外及轉基因動物體內可明顯刺激b細胞的生長，免疫球蛋白分泌，並導致動物自身免疫性改變。 -
It is interesting that pma plus calcium ionophore a23187 can inhibit pma - induced pta1 expression, and this effect ca n ' t be reversed by calcmeurin inhibiter fk506. pta1 mabs can inhibit ctl activation and differentiation in mixed lymphocyte culture system when added at the beginning of the culture but can induce platelet activation and aggregation in the fc dependent manner. in 1997, pta1 cdna was cloned from cdna library of tpa activated jurkat cells, which belongs to immunoglobulin superfamily ( igsf ) with two v - like domains of extracelluar region of pta1
Il - 2 、 tnf - 、 pma可以使t細胞pta1表達上調， tgf -可以下調pta1的表達，而pma加上鈣離子載體a23187可以顯著抑制pma的上調作用，且這種抑制作用不被calcineurin抑制劑fk506所逆轉， 1997年burns教授從pma活化的jurkat細胞cdna文庫中克隆了pta1cdna全長，證實pta1是一個新分子，屬于免疫球蛋白超家族，胞膜外區有兩個v樣結構域。 -
After thymus transplantation, the embryo ' s thymus has trunk cell that comes from the embryo ' s yolk bag, embryo liver and marrow, it excretes a great deal of thymus hormone which change lymphocyte into mature t lymphocyte through multiplication and differentiation, then it help to turn b cell into serous cell, the quantity of the serous cell increases, the antibody that it produces also increases, that is the content of iga, igm and igg is increased
而移制胎兒胸腺后，由於胎兒胸腺內有來自胎兒卵黃囊、胚肝和骨髓的幹細胞，並能分泌大量胸腺素，促進淋巴細胞在該處增殖、分化為成熟t淋巴細胞，繼而輔助b細胞活化成為漿細胞，漿細胞數量增加，產生的抗體量增加，即igg ， igm ， iga含量增加。 -
Porcine il - 12 ( pil - 12 ), also termed as natural killer cell stimulatory factor ( nksf ) and cytotoxic lymphocyte maturation factor ( clmf ), can induce some cytokines, particularly ifn -, from t and nk cells, as well as enhance the cytotoxic activity of these cells. its most critical role may be to initiate the development of cell - mediated immunity by promoting the differentiation of th1 cells from naive t cells
白細胞介素- 12 （ il - 12 ）又名nk細胞刺激因子（ nksf ）或細胞毒淋巴細胞成熟因子（ clmf ） ，能誘導t細胞和nk細胞產生ifn - ，並增強其細胞毒活性，它的關鍵作用是能誘導th0細胞分化為th1細胞以激發細胞免疫進程。 -
At first, total 31 transcription factors correlated to cell proliferation, differentiation, physiological stress and apoptosis, were selected ( see in article ) to use in the two - hybrid, and cloned into plasmid pact by using rt - pcr to amplify these transcription factors from fetal tissue cdna or stimulated lymphocyte cdna. as result, only six transcription factors atf3, atf4, e2f6, c - jun, c - fos and p53 were correctly cloned
基於以上的背景信息，本文利用細胞雙雜交技術，對resrin在細胞周期中可能的作用的轉錄因子進行了篩選:一、首先從genebank中篩選了31個與細胞周期密切相關的轉錄因子，設計了特異性引物。從胎兒組織和刺激后的淋巴細胞中克隆了這些轉錄因子並構建於細胞雙雜交系統的pact質粒中。
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