major antigen 中文意思是什麼
major antigen
解釋
主要抗原-
A pair of primers were chemically synthesized based on the cdna sequence of hog cholera virus strain brescia and used to amplify the cdna fragments of envelope glycoprotein e2 gene of hclv which coding the major protective antigen by reverse transcription - polymerase chain reaction ( rt - pcr ) from total intact rna extracted from infected calf testicle cell culture by hclv
以豬瘟兔化弱毒犢牛睪丸細胞毒（ hclv ）中提取的細胞總rna為模板，以rt - pcr技術，擴增出了完整e2基因的cdna片段。經電泳、酶切分析，證實了所擴增片段為e2基因特異性片段。 -
Glutamic acid decarboxylase ( gad ) is a major target antigen of humoral and cellular autoimmunity in type 1 diabetes mellitus. the autoantibodies against gades protein is the most early and specific marker for type 1 diabetes mellitus, so it has been applied to the clinical practices widely
谷氨酸脫羧酶（ gad ）是胰島b細胞的一種主要自身抗原，與1型糖尿病細胞免疫和體液免疫有密切關系，已廣泛應用於臨床，作為糖尿病預測、診斷、分型、療效監測的重要依據。 -
Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。 -
The expression conditions of e2 gene in p. pastoris were optimized, the results indicated that the peak obtained after 72 hours ; pattern of inhibition / induction could improve expression level ; the best ph value were between 7. 5 and 8. 0 and the optimized methanol - induced concentration was 2 % - 3 % the e2 genes of the prevalent strain ( guangxi yulin strain ) and c strain derived from rabbit spleen tissue were amplified and cloned into e. coli the expression vector pproex - htb respectively, the recombinant plasmids pproex - gxyl and pproex - c were obtained and then were transformed into the dh5a e. coli competent bacteria respectively, the recombinant bacteria could express the major antigen region of e2 gene, the expression yields amount to 35 % and 38 % repectively
豬瘟病毒ez基因的原核表達： pcr擴增出當前豬瘟流行野毒株，中國豬瘟兔化弱毒（ c株）兔脾組織毒ez基因的主要抗原區，將其克隆到原核大腸桿菌表達載體pproex htb中誘導表達，經sds page檢測表明，重組質粒能表達ez基因主要區蛋白， westernblot檢測表明，誘導表達蛋白與豬瘟陽性血清發生特異性反應，表達量為35和38 ，可用於基因工程診斷抗原。 -
Classical swine fever ( csf ) is one of major contagious diseases in pig breeding industry. in order to gain massive diagnostic antigen csfv, and large scale of csfv specific major protective antigen protein ( e2 envelope glycoprotein ) in eucaryotic cells, which are prepared into subunit vaccine for effective prevention against csf
豬瘟是危害養豬業的主要傳染病，為了得到大量的豬瘟病毒特異性診斷抗原，並試圖在真核細胞中大量表達豬瘟病毒特有的免疫保護性抗原，即e2囊膜糖蛋白，為進一步制備豬瘟亞單位疫苗有效預防本病奠定基礎。 -
Burg jl, perelman d, kasper lh, et al. molecular analysis of the gene encoding the major surface antigen fo toxoplasma gondii j. j immunol, 1988, 141 : 3584
陳曉光，江靜波.應用聚合酶鏈反應技術建立弓形蟲表面抗原基因的克隆與測定j .中國寄生蟲學與寄生蟲病雜志， 1994 ， 12 （ 2 ） ： 129 -
A major component of the antimicrosomal antigen is thyroid peroxidase ( tpo ) which is often measured serologically
抗微粒體抗原主要組成之一是甲狀腺過氧化物酶（ tpo ） ，它可通過血清學方法檢測出來。 -
High - efficiency expression of the major antigen gene vp2 of infectious bursal disease virus in yeast and rudimentary immunization test
2在酵母細胞內的高效表達及其免疫原性研究
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