microtubule protein 中文意思是什麼
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The expressed apoe protein in central neuronal system functions potentially in deposition and clearance of amyloidal peptide, sustaining the stabilization of microtubule proteins, cellular signal transduction, immune regulation, glucose metabolism and oxidation stress. apoe plays a key biological active role in vivo
中樞神經系統中的apoe對腦組織澱粉樣蛋白的沉積與清除、微管蛋白穩定性的維持、細胞信號轉導、免疫調節、葡萄糖代謝、氧化應激等都有潛在的作用， apoe在體內發揮十分重要的生物學活性。 -
It may have a preventional function from alzheimer ' s disease. molecular biological studies are shown that apoe isoform has a isoform - specific role to neurodegeneration. apoe3 and apoei aid to sustain the stabilization of cytoskeleton protein tau, while apoe4hyperphosphorylates tau to destabilize the microtubule protein, which will make neurocyte easy to form neurofibrillary tangles in ad
分子生物學研究發現， apoe異構體對神經細胞退化表現出異構體特異作用， apoe _ 3和apoe _ 2有助於維持微管的穩定性，而apoe _ 4則使tau蛋白超磷酸化，破壞微管的穩定性，使神經細胞易於形成神經纖維纏結。 -
It is known that cells display the abnormal response of autophagy in undergoing the stress, apoptosis, cell death and many diseases. two forms of rat microtubule - associated protein 1 light chain 3 ( mapllc3 ) exist and serve as a subunit of the microtubule - associated protein 1 and an essential constituent of autophagosome membranes, respectively
已經在細胞的脅迫反應，細胞的凋亡和死亡以及很多疾病組織中都發現了自噬囊泡異常的現象，大鼠微管相關蛋白輕鏈3 （ mapllc3 ）蛋白是第一個在哺乳動物細胞中鑒定的定位在自噬體膜上的蛋白。 -
Based on the actual biology settling, kinesin moves along microtubule which is constructed from asymmetrical o and p protein subunits which array periodically, so the microtubule ' s structure is also asymmetrical and periodical. during the motion, kinesin ' s configuration changes in a dynamic - chemical period in which there are several dynamic - chemical states for the motor, and the transitions are random between state and state to a certain extent
根據實際的生物背景，驅動蛋白沿微管作定向運動，構成這些微管的蛋白亞基順序排列，形成非對稱的周期性結構，且驅動蛋白在運動過程中構象發生了變化，在一個力學和化學循環中要經歷多個中間態，各個態之間的躍遷具有隨機性。 -
Two forms of rat microtubule - associated proteinl light chain 3 ( mapllc3 ) exist and serve as a subunit of the microtubule - associated protein 1 and an essential constituent of autophagosome membranes, respectively
大鼠微管相關蛋白輕鏈3 （ map1lc3 ）蛋白在體內同時以兩種不同分子量的形式存在。 -
In the present experiment studies, an acute traumatic model of lateral cortical impact was employed to study expressive changes of microtubule associated protein - 2 ( map - 2 ), cyclooxygenase - 2 ( cox - 2 ), glial cell line - derived neurotrophic factor ( gdnf ), caspase - 3 mrna and protein after brain injury in rats. immunocytochemical staining, western blotting, nucleic acid in situ hybridization with an oligonucleotide probe and computer image analysis were used to detect the dynamic changes of map - 2 mrna, cox - 2 mrna, gdnf mrna, and caspase - 3 mrna in the cortex after moderate traumatic brain injury ( tbi )
本實驗從自行設計大鼠腦損傷落體打擊器開始，先行建立了一個便於觀察和施加處理因素、控制性好、重復性好的動物模型，選用30g擊錘從25cm高處下落，沖擊應力d為355 . 09kpa ，打擊大鼠右頂部，造成中等程度的閉合性腦損傷，從病理形態學、組織超微結構觀察及微管相關蛋白- 2 （ microtubuleassociatedprotein2 ， map - 2 ） 、環氧合酶- 2 （ cyclooxygenase2 ， cox - 2 ） 、膠質源性神經營養因子（ glialcellline - derivedneutrophicfactor ， gdnf ） 、 caspase - 3基因及蛋白表達的時間性變化，詳盡系統地闡述腦損傷后各指標變化的時間規律性及表達差異可能的形成機制。
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