new drug screening 中文意思是什麼
new drug screening
解釋
新藥篩試-
On the one hand, the theoretics of drug discovery become more comprehensive and more profound as the development of numerous new disciplines such as genomics, proteomics, transcriptomics, metabonomics, bioinformatics and system biology ; on the other hand, the pathways for new drug discovery are broadened by the continuous improvement of technological platforms including computer - aided drug design, high throughput screening, high content screening, biochip, transgenic and rnai technology
一方面，基因組學、蛋白質組學、轉錄組學、代謝組學、生物信息學、系統生物學等新興學科的崛起與發展，為藥物發現提供更為廣泛而深刻的理論基礎；另一方面，計算機輔助藥物設計、高通量篩選、高內涵篩選、生物晶元、轉基因和rna干擾等高新技術的發展和完善，為藥物發現提供了新的技術手段和有力工具，極大地拓寬了藥物發現的途徑。 -
The cdna expression library that contains no intron theoretically include all expressed genes and conserve resource genes permanently. lt can be used to find out and clone some genes which can express particular protein with modern molecular biological techniques, such as immunological screening, drug - prob screening, southern et al. lt is very important to study the life nature of plasmodium falciparum in molecular level. with the developments of these studies, the drug - resistant mechanism of the plasmodium falciparum and the genes of some specific medicine binding protein can be made well - known. at the same time, the researches will do good to explain the mechanism of some specific medicines in order to design and screen new anti - malaria drugs
建立cdna表達文庫在一次永久保存基因資源的同時，可以利用功能篩選、免疫學篩選、藥物探針篩選、 southern雜交和大規模序列測定等現代分子生物學技術尋找特異性活性蛋白基因，進而克隆和表達這些基因，對從核酸及蛋白質等分子水平研究瘧原蟲的生命活動規律，對揭示其抗藥性分子機理，搞清某些特效藥物結合蛋白的基因及此類藥物的作用機制，對新型抗瘧藥物的合理設計及篩選都具有極其重要的現實意義。
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