oligodeoxynucleotide 中文意思是什麼

Effect of et - 1 antisense oligodeoxynucleotide on the hemodynamics of normal and experimental hypertensive rats

內皮素- 1前體基因反義寡核苷酸對正常和高血壓大鼠血流動力學的影響

Effects of nuclear factor - b decoy oligodeoxynucleotide on the function of human umbilical artery smooth muscle cells induced by umbilical sera in preeclumpsia

順式誘騙寡脫氧核苷酸對子癇前期患者臍血清培養的臍動脈平滑肌細胞功能的影響

Sodn oligodeoxynucleotide of pkb : 5cac atg gac gtc aaa gct tcc aa3 ' each base of both sodn and saodn oligodeoxynucleotide was sulfurated. methods 1. superovulation, natural mating and eggs collection

Myt激酶的作用與cdc25相反，可以持續的使edcz的nlr14和t 」巧處于磷酸化狀態而抑制mpf的活性，從而抑制細胞周期進程。

Rt - pcr kit was from takara technology co. ltd. the sequence of the primer of pkb are shown below, together with all the sodn and saodn oligodeoxynucleotide were synthesized in takara technology co. ltd. pkb primers ; forward primer 5 ' cga gaa gcc gcg acc caa cac3 ' and reverse primer 5atg cac tac cgc cgg a3 "

有絲分裂前， cdcz / cy山b 、組蛋白h ;激酶的活性通過被weel和myt激酶磷酸化cdcz的1卜巧和thr14殘基而抑制。在有絲分裂期mpf可以被cdc25活化，這兩個位點被去磷酸化， cdc25是蛋白水解酶，可以使cdcz的t打巧脫離磷酸化。

Local delivery of c - myc antisense oligodeoxynucleotide on vessel wall to prevent restenosis following ptca

術后再狹窄的防治作用機制

B - actin primers : forward 5tcc tat cgg cct cct cct ac 3 " and reverse 5aga atg tag tcc gcc agg tc 3 ", designed for 200bps. saodn oligodeoxynucleotide of pkb : stac agc ctg aga gga cct acc tg3 "

在有絲分裂期， edc25經歷216位ser磷酸化同時其水解酶活性增強，活化的mpf磷酸化並活化edc25 ，形成正反饋，結果進一步活化mpf前體，活化的mpf促進細胞周期g2 / m期轉換。

Inhibition of antisense oligodeoxynucleotide for tissue factor to myocardial ischemic - reperfusion injury

組織因子反義寡脫氧核苷酸防治心肌缺血再灌注損傷的實驗研究

The molecular mechanism of the apoptosis in ovarian cancer cells induced by antisense oligodeoxynucleotide of human telomerase reverse transcriptase

基因反義核酸誘導卵巢癌細胞凋亡的研究

To make clear the hypothesis, a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study, respectively. we first studied the cellular localization of kvl. 2 and the co - localization of kvl. 2 protein and vegf receptors flk - 1 and flt - 1, observed the effect of mcao on kvl. 2 expression and phosphrylation in the rat brain in vivo, then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl. 2 in sh - sy5y cells. finally, in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl. 2 phosphorylation, we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl. 2 phosphorylation

為了驗證上述假設，本文分別在整體和離體水平，採用大腦中動脈缺血（ middlecerebralarteryocclusion ， mcao ）和體外氧?糖剝奪（ hypoxiaandglucose - deprivation ， hgd ）缺血模型，首先了解了kv1 . 2蛋白的細胞定位及與vegf受體flk - 1和flt - 1的共存情況，觀察了整體mcao后缺血再灌不同時間大鼠腦內kv1 . 2蛋白的磷酸化水平變化，然後通過外源性給予vegf蛋白，在sh - sy5y細胞株上觀察其對缺血細胞存活率及kv1 . 2蛋白磷酸化水平的影響，最後利用vegf反義脫氧寡核苷酸（ oligodeoxynucleotide ， odn ）特異阻斷內源性vegf蛋白的表達，觀察內源性vegf蛋白在缺血細胞損傷及調節kv1 . 2蛋白磷酸化中的作用，以進一步明確vegf缺血保護效應與其調節kv1 . 2蛋白磷酸化之間的關系。

Both cdc2 and cdc25 kinase activity were inhibi - ted by ly294002 and saodn oligodeoxynucleotide of pkb, which indicate that pkb may act as an initiator of g2 / m phase transition through the phosphoryla - tion of cdc25c at ser216

Pi3k介導的信號轉導通路中， pi3k pkb是獨立於其它通路的一個新發現的信號轉導通路，且與ras ， g蛋白， pkc等有復雜的交互作用。

In this paper, a series of transition metal complexes were synthesized ; interaction and reaction mechanism between complexes and dna were studied. in addition, we synthesized and analyzed a sequence - specific cleavage reagent, in which oligodeoxynucleotide was recognizing group. detailed work mentioned below were carried out : 1

本文在查閱大量文獻的基礎上，以1 ， 10 -鄰菲咯啉和1 ， 10 -鄰菲咯啉- 5 ， 6二酮為配體合成了一系列過渡金屬配合物，詳細研究了它們與pbr322dna的相互作用及其機理。