pathogenicity island 中文意思是什麼
pathogenicity island
解釋
毒力島- pathogenicity : n. 【醫學】致病力，致病原因。
- island : n 1 島，島嶼。2 島狀物；孤立的地區；孤立的組織。3 【造船】航空母艦或船隻的上層建築〈如艦橋、艦臺...
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The results showed that the f fragment, 728bp in length, could be a new gene with a little homology to the genes coding for polyketide synthetase or fatty - acid synthetase and the b fragment, about 4kb in length, is inferred to have repeat sequences around tn5 insertion site, in which there is homology to the wa 314 right arm of the high - pathogeniciry island of yersinia enterocolitica. to reveal any pathogenicity of enterobacter cloacae b8 and its mutated strains b8b and b8f to animals, the experiment with mice was carried out
結果顯示， f片段長度為728bp ，與現有生物數據庫的blast比較分析，發現該序列僅有局部短於1oobp的區域與polyketide合成酶基因或與脂肪酸合成酶基因有低的同源性，推測為一新基因； b片段長約4kb ，序列拼接結果推測靠近tn5插入位點部位有重復序列，對b片段tn5遠端的部分序列進行blast比較，發現它與小腸結腸炎耶爾森氏菌的強毒力島有一定的同源性。 -
To dress the question if other virulence gene were present in this kind of strains, 152 of 436 irp2 - hybridized strains were re - confirmed and selected for this study. the virulence genes or putative virulence genes detected by pcr or hybridization include heat stable toxin ( st ) & heat labile toxin ( lt ) for enterotoxigenic e. coli ( etec ), invasive plasmid antigen b ( ipab ) for enteroinvasive e. coli ( eiec ), epec adherence factor ( eaf ), epec secretion protein c ( espc ) for enteropathogenic e. coli ( epec ), hemolysin ( hlya ) and shiga toxins ( sltl and slt2 ) for enterohaemorrhagic e. coli ( ehec ) and eaggec probe for entero - aggregative e. coli ( eaggec ). the prra and yc73 genes of pathogenicity associated island ( pai ) of urepathogenic e. coli ( upec ) and " o " island 28 ( rtx 615 ) gene was also detected, the later was a newly discovered putative pathogenicity island in e. coli o157 : h7
為探討攜帶小腸結腸炎耶爾森氏菌的hpi毒力島的大腸桿菌是否具有其他已知的毒力基因，選取82株由原位雜交和pcr方法初篩irp2陽性的大腸桿菌菌株，進行在致瀉性大腸桿菌的25個毒力基因的檢測，包括腸產毒性大腸桿菌的熱穩定毒素st和熱不穩定毒素lt ，腸侵襲性大腸桿菌的侵襲蛋白b基因ipab ，腸致病性大腸桿菌的eaf 、 espc基因，腸出血性大腸桿菌的溶血素hly 、志賀毒素1 （ slt1 ） 、志賀毒素2 （ slt2 ）基因，腸集聚性大腸桿菌的eaggec探針，以及在泌尿道致病性大腸桿菌和o157 ： h7大腸桿菌中新發現的毒力島基因。 -
The pathogenic strains of yersinia enterocolitica carry a 45 - kb high pathogenicity island ( hpi ) comprising iron - uptake - related genes such as irp1 - irp2 and fyua, which has been observed in 93 % of the 60 entero - adhesive e. coli { eaec } strains and 80 % of the e. coli isolated from blood samples
Hpi毒力島功能核心區主要的結構基因為irp2 、 irp1和fyua ，是高度保守的。 irp2和irp1分別編碼兩種高分子量蛋白hmwp2和hmwp1 ， fyua編碼鼠疫菌素受體。 -
Many pai have been discovered in many pathogens to humans ( pathogenic e. coli, yersiniae spp., salmonella spp., vibrio cholerae et al. ) - among them, the pai of yersiniae which encodes siderophore yersiniabactin ( ybt ) system is designated high - pathogenicity island ( hpi ). hpi is essential for the mouse virulence in yersiniae
其中，耶爾森菌中的一個與鐵載體? ?耶爾森桿菌素（ yersiniabactin ， ybt ）合成轉運和調節有關的毒力島被稱為hpi毒力島（ high - pathogenicityisland ， hpi ） 。 -
Virulence genes of pathogenic bacteria can be located on the chromosome where they may be organized as so - called pathogenicity island ( pai )
細菌毒力島（ pathogenicityisland ， pai ）是指染色體上成簇排列的與細菌毒力密切相關的基因簇。 -
The reason that different distribution frequency of hpi in various e. coli is unclear, either. as the high frequency distribution of hpi in eaggec, this study will focus on the following parts to discuss the function of yersiniae high - pathogenicity island in enteroaggregative e. coli
鑒于hpi在eaggec中的高頻分佈，本研究擬從eaggec菌株出發，著重從以下幾個方面對eaggec攜帶的hpi毒力島的功能進行了研究。
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