pdtc 中文意思是什麼
pdtc
解釋
二硫氨基甲酸肽吡咯烷-
There are still many questions remain unanswered, including the mechanisms that specify oligochitosan recognition, the participation of additional molecules in transmembrane signaling, and the repertoire of downstream pathways activated by oligochitosan. it was also observed that pdtc did not totally block no production, which gave us another evidence that there must be some other signal transduction pathways ( perhaps mapk, pkc, ca2 + dependent signaling ) involved in the activation, so further investigation is necessary to clarify molecular mechanism of oligochitosan inducing immunological en
Westemblot結果顯示100林歲ml劑量的殼寡糖作用於raw264 . 7細胞（ 4x105個細胞/ ml ） 4h ，胞核內p65的含量明顯增加， 6h時達到高峰， 10h時恢復到基礎表達量，這就提示在殼寡糖對巨噬細胞的激活過程中nf一kb活化狀態可以持續6個小時。 -
The protein level of nf - kb in nucleus peaks at 6 h after stimulation and persists for at least 6 h. pdtc ( pyrrolidinedithiocarbamate ), an inhibitor of nf - kb, the effective concentration of it for nf - kb inhibition without any toxicity on cells is up to 100 umol / l, can significantly block no production induced by oligochitosan. although the study reported herein reveals that oligochitosan induces no production via nf - kb in macrophage, which is an important signaling mechanism of oligochitosan inducing immuno - enhancement of macrophage in vitro
加入100林mol / l劑量的nf一忍抑制劑毗咯烷二硫代氨基甲酸鹽（ pnte ）作用於rawz 「 . 7細胞（ 4火10 ，個細胞/ ml ） 90rnin ，然後再加入100林留而劑量的殼寡糖對巨噬細胞進行刺激，發現pdtc在各個時間點（ 6 、 12 、 18 、 24h ）都明顯抑制殼寡糖對巨噬細胞no的誘導作用。
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