pharmacophore 中文意思是什麼
pharmacophore
解釋
藥效基團-
This is because once a pharmacophore is known, medicinal chemists can modify it to reduce toxicity while maintaining ( or enhancing ) potency
這是因為一旦知道藥效基因，藥物化學家就可以修飾它，在保持藥效的基礎上減少毒性。 -
The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models
本文綜述了近年來酪氨酸激酶抑制劑的研究進展，包括抑制劑的結構和與激酶作用的藥效團模型。 -
Numerous approaches for studying drug leads and their measurable activity against a particular target have been developed, allowing one to infer the pharmacophore from a series of these structure - activity relationships
人們已經發展了很多研究藥物先導物和其針對特定靶子的可測量活性的方法，使得研究者能夠從一系列結構活性關系中得到其藥效基因。 -
Typically, pharmacophore refers to the combination of atoms and functional groups ( together with their three - dimensional positions ), that together allow a drug to interact with its target protein in a specific manner and exhibit its pharmacological activity
一般而言，藥效基因是指原子和功能基團的結合，使得藥物以特定方式與靶蛋白作用並顯示藥物活性。
分享友人