positional cloning 中文意思是什麼
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Introduction positional cloning of disease genes and research of protome become very important in the post - genome period after completion of human genome project ( hgp ). positional cloning is a new mean with the developing of hgp
前言人類基因組計劃的測序工作完成之後,已進入后基因組學階段,疾病基因的定位克隆及其蛋白質功能研究已成為研究的重要內容。 -
Its virtue is to hold the relationship between phe - notype and gene. it is difficult to be replaced by other means because the gene decides the phenotype. the most classic positional cloning is " cdna - dependent ", including cdna selection, different display and subtractive hybridization
該方法最獨特的優點是抓住了「表型」與「基因」的聯系,基因的功能是決定某一表型,因此,通過明確的表型來鑒定某一基因存在的位置與功能,是其它非遺傳技術難以取代的。
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