prion 中文意思是什麼

prion 解釋
n. 名詞 【生物化學】朊病毒，感染性蛋白質。

  1. There is currently no treatment for prion diseases, which include cjd in humans and boine spongiform encephalopathy ( bse ) in cattle

    目前還沒有普粒子疾病的治療辦法，包括人類的克雅氏病（ cjd ）和牛腦海綿狀病（瘋牛病， bse ） 。
  2. Researchers have also made some headway in treating a human prion disorder called creutzfeldt - jakob disease ( cjd ), which today is uniformly fatal

    另外，研究人員也在治療庫賈氏癥（ cjd ）方面取得某些進展，人類的這種普恩蛋白疾病在今天還是無藥可治的絕癥。
  3. Research progress on prion and prion disease therapy

    朊病毒和朊病毒疾病治療的研究進展
  4. In prion year whose output value reached 20 million yuan

    上年實現產值2000萬元人民幣。
  5. Strategy of construction the prion promoter - less knock - out vector

    朊蛋白基因敲除無啟動子打靶載體的構建策略
  6. What is even more peculiar : exactly the same prion proteins occur in healthy animals

    更奇特的是：這種蛋白質在健康動物中也存在。
  7. Prion diseases are always fatal, often, however, not until months after the outbreak of the disease

    致病性的朊病毒蛋白質在腦中沉積並損傷腦組織。
  8. Can link with tyr, thus results in prion ' s aggregation with the extension of the reaction chain

    可與正常tyr殘基發生交聯反應，隨著反應鏈的延伸，最終導致prion的聚集沉澱。
  9. Such examples are given as the blood filtering principal of hemoglobin, catalysis of enzymes, immune recoglization, prion, glycoprotein and the relationship of structure and function of membrane protein, et al, as well as the applications to medicine

    在簡要介紹結構生物學的研究方法的基礎上，主要從分子水平闡述蛋白質和核酸的結構原理、相互作用、結構與功能的關系，通過具體實例闡述血紅蛋白的輸氧機制、酶的催化機制、免疫分子識別、朊病毒、糖蛋白、生物膜的結構功能關系等，以及結構生物學在醫學上的應用。
  10. They occur when normal prion proteins become knotted and resistant to being broken down, and cause rapid brain degeneration that is ineitably fatal

    當正常的朊病病毒多節化並具有了抗破壞能力的時候，這些疾病開始出現；接著導致不可避免的致命的迅速腦部惡化。
  11. Preious work has shown that mice with their prion gene knocked out remain healthy, and when inoculated with scrapie are protected against the disease1

    先前的工作已經告訴我們，被敲除普粒子基因的老鼠仍然健康，並且當嫁接羊瘙癢病的時候它們能夠抵禦疾病。
  12. It was found that prion which is made up of proteins exclusively is the main cause and it has two forms, i. e, normal form prpc and abnormal one prpsc

    目前已知瘋牛病的致病因子是完全由蛋白質組成的朊病毒（ prion ） ，它存在「正常」和「致病」兩種狀態，分別被稱為prp ~ c和prp ~ sc 。
  13. The evidence is accumulating that prion diseases are due to proteins which change their conformation irreversibly during an association reaction, perhaps by mechanisms related to amyloid accumulation

    越來越多的證據指出蛋白感染素疾病（如狂牛病）是因為蛋白質結合過程中其構型產生不可逆的改變，可能是由類澱粉體堆積相關的機製造成。
  14. The prototypic prion disease found is scrapie. the epidemic of bse in england and the newly found vcjd in human attracted more attention to prion diseases and the disease - causing proteins

    羊瘙癢癥是最早發現的朊蛋白病，而瘋牛病在英國的流行以及新近發現的新變種的人類雅各布氏病引起研究者們對朊蛋白疾病及其致病蛋白的更大關注。
  15. The history, situation, clinical symptom, detection of bse, hypothesis of prion and protein, mechanism of bse were reviewed. and the possibility of curing bse was elucidated

    摘要論述了瘋牛病的發病歷史與現狀、瘋牛病的臨床癥狀與檢測、朊蛋白與蛋白假說和瘋牛病的致病機理等。此外，還討論了治愈瘋牛病的可能性。
  16. Its breakout in europe caused a great loss and society turbulence and there have been intensive researches on prion about its origin and effective therapy in life science in recent years

    以瘋牛病為例，近年來它在歐洲的大爆發引起巨大的財產損失和社會動蕩，因此研究瘋牛病的致病機理及有效治療方法是生命科學領域的熱點課題之一。
  17. There exist two prion protein forms, the pathological form, prpsc ( sc stands for scrapie ), and normal cellular form, prpc ( c stands for cellular ). these two proteins have the same amino acid se quence, the only difference lies in conformation

    研究得知朊蛋白有兩種形式，一種為致病形式（ prpsc ， sc是瘙癢癥的縮寫） ，另一種為組織內正常存在的細胞形式（ prpc ， c是細胞型的縮寫） ，這兩種蛋白在一級結構的氨基酸序列相同，僅構象有不同。
  18. A single protein plays a major role in deadly prion diseases by smashing up clusters of these infectious proteins, creating the " seeds " that allow fatal brain illnesses to quickly spread, new brown uniersity research shows

    布朗大學最新研究顯示，有一種蛋白可能是朊毒病中關鍵蛋白，裂解感染性蛋白生成「種子」片段，然後侵襲腦組織致宿主迅速死亡。
  19. The facts that cellular prion protein is extensively distributed among tissues, its high similarity in different species and its indispensability in prion diseases development established its importance in the study of prion diseases

    細胞型骯蛋白（ prpc ）在組織內分介廣泛、在物種問高度保守並且在骯蛋白疾病的發生中不可或缺，這些特點決定了它在骯蛋白疾病研究中的重要地位。
  20. The propagation mechanism of the prion diseases is widely accepted that prpsc transforms prpc into the pathological form and more and more prpsc will gradually be produced and forms larger fibrillar aggregates. when a critical level of prpsc has accumulated, the neurons die, resulting in large vacuoles. the affected brain regions become sponge - like in appearance, hence the name spongiform encephalopathies to describe all prion diseases

    目前普遍接受的朊蛋白疾病發生機制為prpsc轉化prpc為致病形式，致使越來越多的致病蛋白形成並堆積成越來越大的纖維狀聚集物，當致病蛋白聚集到一定程度，造成神經元死亡而使受累腦區呈現海綿樣空洞，這也就是為什麼用海綿樣腦病來描述所有的骯蛋白疾病。
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