proline rich domain 中文意思是什麼
proline rich domain
解釋
脯氨酸富含區-
Pp38 was found to have immunosuppressive effect on chicken in vivo and the copy number of 132 - bpr was found to be associated with the attenuation of the virus in vitro, meq was believed to be a potential oncogene, based on its leucine zipper structure and proline - rich domain characteristic of jun / fos family of transcription factors, and may plays an important role in the pathogenicity or oncogenicity of mdv
其中， meq與132 - bpr兩個基因是mdv - 1所特有，已證實132 - bpr的拷貝數與毒株的體外致弱程度有關， pp38則被證實可抑制機體的免疫應答。 meq基因由於具有與致瘤基因jun fos家族類似的分子結構，因此，我們有理由認為meq基因在mdv致病、致瘤中可能發揮重要的作用。 -
The intracellular domain has four distinct regions : the ram domain, the ankyrin repeats, a transcriptional activator domain ( tad ) and the pest ( proline -, glutamate -, serine -, threonine - rich ) sequence. two nuclear localisation sequences are present prior to and following the ankyrin repeats
釋放的胞內區不經其它信號轉導分子的作用可直接進核，與dna結合蛋白rbp - j相互作用並激活下游基因如果蠅的e （ spl ） （ enhancerofsplit ）復合體及哺乳類的hes （ hairyandenhancerofsplit ）家族基因。 -
Lfy and lfy - like proteins from angiosperm contain a proline - rich region near the amino terminal and an acidic central region which is typical for transcriptional activators and may be important for the function of lfylike protein. the two domain exists in the variable regions of all lfy - like proteins
與擬南芥leaf 』 y基因相比較，銀杏ginlfy和g毗基因沒有做為轉錄激活區域的位於氨基酸序列中間的酸性區和位於n端的富含脯氨酸區，但這兩個區域均位於leafy基因的非保守區。
分享友人