receptor membrane 中文意思是什麼
receptor membrane
解釋
受體膜-
Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis
首先，用~ （ 35 ） s標記的氨基酸混合物喂養工程菌成功地制備了~ （ 35 ） s標記的擬南芥鈣調素（ ~ （ 35 ） s - cam ） ， ~ （ 35 ） s - cam純度高、放射活度高、 ca ~ （ 2 + ）與egta存在時的電泳行為與未標記cam相同，可作為一種高靈敏性的探針用於進行受體學分析實驗；用擬南芥種子誘導愈傷，通過酶解制備了大量原生質體。 -
However, the receptor and translocation domains of the colicin ia can only recognize the inner and outer membrane receptors of the escherichia coli, therefore the wild type colicin ia can not be developed into antibiotics against other types of bacteria
然而由於其信號識別結構域只能識別大腸桿菌外膜和內膜上的特異受體，因此野生型大腸菌素難以拓展成為對抗它種細菌的抗菌素。 -
In the 1990s, the pheromones of gram - positive bacteria, which regulates the growth and toxin secretion of the same type bacteria, were identified they were peptides consisted by dozens of amino acids. the pheromones can auto - recognize membrane receptor of the identical types of bacteria. we had constructed a fusion protein named pheromonicin by introducing a staphylococcal pheromone agrd at the c - terminal of the colicin ia
丘小慶等利用信息素的自主導向特性和大腸菌素ia的致死性通道特性構建了由金黃色葡萄球菌信息素agrd和大腸菌素ia組成的融合蛋白，命名為pheromonicin ，該蛋白表現出了信息素和大腸菌素ia都不具有的抗金黃色葡萄球菌活性。 -
The matter that causes constipation of esophagus cancer patient is relatively complex, it is the patient takes food as a result of deglutition difficulty or ache above all decrease, especially the food intake with cellulose high content decreases, food is gender, chemical to the machinery of gastric bowel gender and temperature stimulation are abate, the receptor of gastric bowel mucous membrane is stimulant reduce, peristalsis decreases
造成食道癌患者便秘的原因較為復雜，首先是病人由於吞咽困難或疼痛而進食減少，尤其是纖維素含量高的食物攝入減少，食物對胃腸的機械性、化學性及溫度刺激減弱，胃腸粘膜的感受器興奮性降低，蠕動減少。 -
For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development
如g蛋白偶聯受體通過g蛋白介導產生胞內信使（ camp ， cgmp ， dg ， ip _ 3 ）將胞外信號傳遞到胞內，從而引起生物學效應；內質網上也存在著一些跨膜蛋白，其中一些與蛋白質的合成及運輸有關，一些與物質代謝有關，如葡萄糖- 6 -磷酸酶。 -
It was important glucoprotein modulating cell functions by combination to idiosyncrasy receptor on cell membrane, which inducing process of cascade signal magnifying, then passing signals into nucleus to induce the modulation of the serial gene expression and viarous physiological reaction, and inhence immunity and antivirus
人-干擾素（ hu - - ifn ）是人體因病毒感染或其它誘生劑作用等所產生的一類非特異性抗病毒物質，是調節細胞功能的一類重要的糖蛋白。 -
Nogo - 66 receptor, ngr, cloned in 2001, is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth. both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains. northern blot, in situ hybridization, western blot and immunocytochemistry analyses show that in addition to oligodendrocytes, nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord, nogo - a is also found in peripheral organs such as heart and testis
Northernblot 、原位雜交、 westernblot和免疫組化結果證明： nogo amrna和nogo蛋白除了在cns的寡突膠質細胞中表達，還表達于發育階段和成年的腦、脊髓和外周神經節的某些神經元中，在外周組織如睪丸和心臟也有表達； nogoe在cns和pns以及多種外周組織中有廣泛分佈； nogo （除表達于腦和心臟外，在骨骼肌中有較高表達。 -
Plant defensin disrupts the cell membrane of phytopathogen differently from cema that contacts directly with the cell membrane. plant defensins are thought to interact with specific receptor harboring in the cell membrane
由於對真菌，特別是絲狀真菌有很強的抑制作用，而對植物細胞沒有毒害作用，防禦素有望在植物抗病基因工程中得到廣泛應用。 -
The cyst cells enclosing spermatomeres maybe synthesize a kind of scf - like protein, which can recognize specially the c - kit receptor on the cellular membrane of spermatomeres. then c - kit is activated, dimerizing and autophosphorylating. at the same time, the tyrosine kinase domain of c - kit is activized, which phosphorylates the proteins that have sh2 domain
精母細胞周圍的囊細胞可能合成scf樣蛋白，特異地識別精母細胞膜上的c - kit受體，並刺激c - kit發生二聚化、自體磷酸化，激活胞內酪氨酸激酶活性，活化具有「 sh _ 2結構域」的靶蛋白，可能通過一系列信號級聯，最終激活與減數分裂的相關蛋白或基因。 -
A c a2 + / calmo dul in - dep endent pro te in kinas e i i ( c amkii ) antagoni st kn - 6 2 ( 5x l0 - ' mol / l ) presented in the intemal solution had no significan effect on the current peaks induced by extracellular nmda ( l0 # mol / l ), but prevented the inhibitory effect of b on inmda " these results indicate that gcs have rapid, reversible idebitory effects on lnmda intracellular application of b thiough microelectrode had no effect on inmda, howevet, extracellular application of b or b - bsa suppressed peaks of inmda : all these denote b exerts its influence on nmda receptor by cytoplasm membrane mechansms, which is naxnely rapid, nongenomic mechhasms
加有快速、可逆的。非濃度依賴性抑制作用。通過微電極將b直接導入細胞內， inmda不受影響，而胞外給予b或besa ， inmda減小，提示b對nmda受體的調控通過膜機制產生，這種作用與經典的基因組機制不同；因為廣譜激酶抑制劑和特異的pka抑制劑均可翻轉b的抑制效應， camk11抑制劑也可阻斷b的效應，而這些激酶抑制劑本身對inmda即有強烈的抑制作用： pka激動劑本身對inmda無明顯作用，也不影響b對l 。 -
Rubber tree ( hevea brasiliensis ) is an important economic woody - crop in tropical areas. its latex is the unique source of crude rubber used in current industry. because of its special and important use, the rubber tree has been extensively planted in tropical areas. increase production is always the main target in rubber tree cultivation. since the ethrel was applied in increasing latex production in 1968 for the first time as a chemical stimulant, not only the latex production had been increased largely, but also a new set of rubber tapping system had been established, leading to a series of economic benefit. owing to ethrel " s extensive application, its side effects had been found more and more obviously, such as tapping dry, speeding up senescence, shortening the life span of rubber tree etc. in order to overcome the side effects and increase production more availably, for a long time, people had carried out lots of research work on cell level, membrane level, physiology and biochemistry of laticifer contents. but the mech anism why ethrel increased latex production was not yet understood completely. this study had cloned the ethylene receptor gene ( efrl ) from rubber tree, and researched the relationship between etrl expression in laticifers and ethrel stimulation on transcription level and protein translation level. the results were as follows : 1
但是，由於乙烯利應用的普及，乙烯利刺激割膠引起橡膠樹發生死皮病及加速膠樹衰老，縮短膠樹壽命等副作用也越來越明顯。為了克服這些副作用，使乙烯利能更有效地刺激增產，長期以來，人們在細胞水平、膜水平和乳管細胞內含物的生理生化層面上進行了大量的研究，但仍未完全了解乙烯對膠樹的作用機制。本研究從分子水平入手，克隆橡膠樹的乙烯受體基因（ etr1 ） ，並在轉錄水平和蛋白質翻譯水平上研究etr1基因在乳管細胞中的表達及與乙烯刺激的關系，取得了以下結果： 1 -
An array of regulatory proteins have been found, which inhibit the formation of central enzymes involved in early stages of the complement activation pathway. these include membrane cofactor protein ( mcp cd46 ), decay - accelerating factor protein ( daf cd5 5 ), complement receptor 1 ( cr1, cd35 ), as well as cd59, which inhibits formation of the membrane attack complex during later stages. these regulatory factors are widely expressed and abundant on many cells, and in fluids of reproductive system
目前發現，機體多種細胞以及生殖系統的體液中表達和分泌豐富的補體調控蛋白，包括作用於補體活化早期階段的cd55 、 cd46 、 cd35和作用於補體活化終末階段的cd59 ，它們分別通過抑制補體活化過程中關鍵的c3 、 c5轉化酶和抑制形成膜攻擊單位，抵抗補體對自身組織細胞的攻擊。 -
Resent studies demonstrate that, such as gabaar1 subunit of gaba receptor, ka2 and glur6 subunit of ka receptor, there are some functional regions in that of c terminus which can regulate these subunits targeting to the cell membrane surface. while little was known whether nmda receptor ' s nr2b subunit has the similar domains
最近有一些研究報道，許多突觸受體如gaba （ b ）受體rl亞單位、 ka受體的kaz和glur6亞單位以及孤兒受體腿亞單位的胞內區，存在有影響受體運輸到細胞膜的功能區，但是尚未有對于nmda受體的nrz亞單位膜運輸的報道。 -
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells
粘合素，或粘合素受體是細胞膜中一種必須的膜蛋白質。 -
There are a and 3 subunits of estrogen receptor ( er ) subtypes. they are different in their distribution, density and mediated action. er can be expressed in nucleus or in cellular membrane
雌激素受體（ er ）屬于類固醇受體超家族的核受體，具有a和日兩種亞型，此二者在各種組織分佈及密度各異。 -
In n terminal, 3 conserved sequences, wxixgmxgxgkttla, l ( i / v ) ( v / l ) lddv ( w / d ) and sriixttrd xxv are in term of p - loop, kinase 2 and kinase 3a. those are highly identical to the homologous of human ( apaf - 1 ) and namenode ( ced - 4 ). it revealed that tm - 22 encodes a membrane protein with a receptor structure and kinase property and may function in ion flow, phosphorylation and proteins interaction
Tm一夕基因的編碼蛋白在該區與tm一2有32個氨基酸的差異，主要集中在第10 、 11和12個亮氨酸重復序列中，與tm一2有兩個氨基酸的差異，僅僅是位於第12個亮氨酸重復序列中的767和769兩個位點，這表明:第一， lrr是tm一22基因和tm一2基因編碼蛋白對病毒識別的特異區段;第二， 767和769兩個位點的差異氨基酸是tm一22基因和tm一2基因編碼蛋白對病毒識別的特異位點。 -
It is well known that paf, a membrane lipid derivative molecule, is increased duing ischemia and hypoxia, which stimulates the further release of glutamate at presynaptic endings. ginkgolide b, one of the component of ginkgo biloba leaves, is a potent paf receptor antagonist
研究者們在篩選和尋找防治缺血缺氧性腦損傷的過程中，已經確實證明了天然銀杏葉的組分之一ginkgolideb是一種強有力的高特異性天然paf受體拮抗劑，可與位於突觸前膜的特異性paf受體結合。 -
A single molecule of rta is able to depurinate 1500 - 2000 ribosomes per minute. ricin b chain ( rtb ) is a galactose - specific lectin which binds to the receptors on cell surfaces, and may enhance rta translocation by forming a pore in the membrane of intracellular organelles. ricin enters the cells by receptor - mediated endocytosis
內吞進入細胞的蓖麻毒素一部分返回到膜表面，一部分經早期內體至晚期內體，最後在溶酶體中降解，只有一小部分約5到達高爾基體，隨后逆轉運到粗面內質網，在那裡rta才和rtb解離，游離出有催化活性的rta 。 -
C - kit is a receptor tyrosine protein kinase on the cellular membrane, while c - myc is a transcription regulatory factor in the nucleus
Kit是位於細胞膜上的受體酪氨酸蛋白激酶， myc是位於細胞核內的轉錄調節因子。 -
1 research papers about following topics a. drug - biomacromolecule enzyme, receptor, membrane, and nucleic acids etc interactions
1研究論文，通常有如下專題：
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