repressor 中文意思是什麼
repressor
解釋
壓抑劑-
To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei, and to study the function and mechanism of mint - mediated transcription repression, yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5, amino acids 2226 - 2959 ). from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo, fifty - one were positive for nutritional screening and p - galactosidase assay. restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments, which are mint, alpha a - crystallin - binding protein i ( alphaa - crybpl ), and nuclear receptor co - repressor 1 ( n - corl ), respectively
鑒于mwt基因編碼區較長,共有10799個堿基,故此我們將mint分為六段,分別命名為fi一f6 ,本研究以其中的f5 ( 222e959 )和f6 ( 296s576 )片段為研究對象,將h者分別插入pgb盯7載體中,結果顯示: mintfs可與核受體輔助抑制因子1階cori ) , o晶狀體蛋白結合蛋白1hlphatcrybp入及mw加互作用,而f6可與igm的重鏈恆定區、泛素結合酶2l6和一個未知功能的新的蛋白基因進行結合。 -
The repressor is essentially a negative control mechanism.
阻遏物基本上是一種負控制機制。 -
The regulator may code for a repressor protein that switches off an operator gene ( in bacteria )
調解基因可能編碼一種抑制蛋白,能夠關閉一個操縱基因(在細菌中) 。 -
Aes contains a glutamine - rich ( q ) domain in its n - terminal, which sharing high homology with the amino terminal region of groucho / tle ( transducin like enhancer of split ). the function of aes is not clear yet, while groucho / tle were found to be a family of transcription co - repressor and play impo rtant roles in notch signaling, wnt - 0 catenin signaling and other transcription regulation events
Aes的n -末端約130個氨基酸中富含谷氨酰眩( q )殘基,形成一個q結構域,與轉錄協同抑制分子tle ( transducinlikeenhancerofsplit )的氨基端高度同源。 -
Effect of extracellular - signal regulated kinase 1 2 specific repressor pd98059 on murine lymphocyte proliferation
98059對小鼠淋巴細胞增殖的影響
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