s antigen 中文意思是什麼

s antigen 解釋
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  1. Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s. despite success of current immunosuppressive drugs, transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft. there are several different mechanisms such as clonal deletion, anergy, neglect, immuno regulation. which maintain tolerance to self - antigen. some strategies, derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection

    二十世紀五十年代以來，器官移植的進展使同種異體器官移植成為治療多種器官終末期疾病的有效手段。盡管目前免疫抑制方案非常有效，但免疫耐受仍是移植免疫學家和外科醫生關注的課題。有多個機制使免疫系統對自身抗原保持耐受，如：克隆清除、忽略、失能、免疫調節。
  2. The western blot analysis show that the antiserum induced by the new antigen plus hemocyanin could bind with the 22kd and 55kd proteins, which were existed in the testis tissue protein of mouse, rat and human. 2 ) the purified peptide emulsified in an equal volume of freund ' s adjuvant and immunized the female balb / c mice with 8 - 10 weeks old. the antiserums and the washings of vaginal membrane were detected by elisa, and shown the highest level of the specific antibody igg was 1 : 6000, while the iga was 1 : 300

    二、 p3多肽與弗氏佐劑混懸后免疫近交系balb c小鼠后，在血清和陰道粘膜沖洗液中可檢測出特異性lgg 、 lga ，最高效價分別達到1 ： 6000和1 ： 300 ；免疫后的小鼠脾臟淋巴細胞增殖率升高，淋巴細胞培養上清液中分泌的il 4和inf y也升高，且以il 4更明顯。
  3. The determination of human thymidine kinase ( htk ) in human serum, which is a key indicator of cancers can give information for the diagnosis and treatment of the malign diseases. the protein a layer was first self - assembled onto the gold electrode surfaces of quartz crystals, the monoclonal antibodies were then orientedly immobilized through the specific binding between the fc terminals of the antibodies and the self - assembled protein a. with this sensor, the affinity constant of antigen - antibody binding was estimated to be 1. 85 106 l / mol according to the scatchard ’ s plotting method, which proved the high bioactivity of antibody. finally, an amplified piezoelectric immunosensor was designed to determine the htk in

    實驗中將蛋白a吸附於鍍金壓電石英晶體電極表面，用於定向固定htk單克隆抗體，成功研製了檢測htk的壓電石英晶體傳感器，並基於標準scatchard繪圖法，計算出免疫反應的親和常數為1 . 85 106l / mol ，證明該單克隆抗體具有較高的免疫活性;同時基於酶催化沉澱技術，設計了的檢測htk的質量放大壓電石英晶體傳感器，該傳感器可在0 . 1 - 10ng范圍內對htk進行定量檢測，應用此傳感器成功地對5種癌癥病人血清中htk的濃度進行了測定，實驗結果為癌癥的臨床診斷與治療提供了參考。
  4. Because of the difficulties on diagnosis and treatment, it is very important for the prevention of trichinosis. trichinella spiralis ( t. s ) has a complex life history and a variety of antigen components, so, despite of a lot of studies, no prevention measures specific for t. s has been found until now

    旋毛蟲病的診斷和治療都比較困難，因而預防顯得尤為重要。由於旋毛蟲生活史的復雜性和抗原的多樣性，雖然近年來許多學者進行了多方面的研究，但迄今為止，尚未發現免疫預防旋毛蟲病的有效措施。
  5. Mosquitoes severely affect people ' s routine life and bring inconvenience through disturbance, sting, and bloodsucking ; sensitization : when a mosquito stings the host, it uses its saliva as a main antigen, which leads to allergic reaction of the host body ( mainly on skin )

    間接危害：蚊類除叮刺、騷擾人類外，主要的危害在於能傳播多種傳染病，如瘧疾（ 1994 、 2004年大亞灣區出現多例病例） 、登革熱（香港、廣州） 、絲蟲病、流行性乙型腦炎等，感染到病毒可使人致殘、致死等，嚴重威脅到人類身體健康。
  6. After the recombinant plasmid pcdna3. 1 / ts87 was identified by digestion of hindlll and bamh i, it transformed into cos7 by lipofectamine. expression product was identified by immunohistochemical method, sds - page and western - blot. the immunocytochemistry result has shown that specific brown - staining grains were found in the cytoplasm of cells transformed by recombinant plasmid versus not seen in cells transformed by pcdna3. 1 or normal cells ; the sds - page result has revealed that a band about 3 8kb was found in cell lysis transformed by recombinant plasmid versus not in cells transformed by pcdnas. l or normal cells ; the western - blot result has showed that only the band about 38kd was recognized by sera from rabbit infected by t. s artificially and sera from rabbit immunized with soluble antigen of t. s and with protein expressed by ts87 gene and by a monoclonal antibody of t. s

    通過細胞的免疫組化，細胞裂解物的sds - page電泳， westem - blot分析檢測目的基因的表達情況。免疫組化結果顯示：重組質粒轉染的細胞質中有棕褐色顆粒，而空載體轉染細胞及正常細胞無此現象；細胞裂解物sds - page電泳結果顯示：只有重組質粒轉染的細胞在約38kd處有明顯的蛋白帶，這與理論計算的ts87基因表達蛋白的分子量為38kd基本一致； western - blot分析結果顯示：約38kd的蛋白帶能夠分別被旋毛蟲感染兔血清，成蟲蟲體可溶性抗原免疫兔血清， ts87基因原核表達蛋白免疫兔血清（ ts87血清）以及一株具保護性的旋毛蟲單抗特異識別。
  7. Cea gene was transferred into human dcs, and specific anti - cancer effecs induced by the vaccine was observed. this test is part of my tutor ' s. hang you - tian has observed the induction of crcinembryonic antigen ( cea ) - specific cytotoxic t - lymphocyte responses in vitro when he transfected dcs with pcdna3 - cea, and has observed the immunity effects of the dcs ( pcea ) inoculateing against to ct 26 ( hcea + ) loaded in balb / c mice. after vaccination with the cea gene - modified dc, the survival time of the mice vaccinated with ct26 + ( cea + ) ws prolonged more potently than that of the mice vaccinatd with other dcs

    癌胚抗原（ carcinoebryonicantigen ， cea ）是一種研廠鄭州大學2002年碩士畢業論文轉染人癌胚抗原真核表達質粒的人樹突狀細胞的抗瘤作用究最為深入的腫瘤相關抗原（ tumorassociatiednigen ， taa ） ，在90的胃腸道腫瘤、 50的乳腺癌及70的非小細胞肺癌中有高水平的表達，是目前國際上公認的腫瘤標志物。
  8. The effect of 20 g / 100 g diet of lactalbumin ( l ), casein ( c ), soy ( s ) and wheat ( w ) protein on the immune responsiveness of c3h / hen mice has been investigated by measuring the humoral immune response to the t cell - independent antigen, tnp - ficoll

    摘要：本研究測量體液對t細胞抗原的免疫反應，探討不同的蛋白補充劑（包括乳白蛋白、酪蛋白、大豆蛋白及小麥蛋白）飼料（ 20克蛋白/ 100克飼料）對小鼠免疫反應的效果。
  9. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  10. If a piece of grafted skin contains an antigen different from the host's, the host will make antibodies against it.

    如果一塊移植的皮膚含有一種不同於宿主的抗原，宿主將產生抗體來對抗它。
  11. Using the grid - type method to partition the space, regarding the modeling data as the antigen and the fuzzy rules as the antibody, this method determines the structure of t - s system with immune theory and adopts the least square method to estimate consequent parameters of the linear rule

    該方法結合網格空間劃分方法，以建模數據為抗原，模糊規則為抗體，採用人工免疫原理確定系統結構，並應用最小二乘方法估計線性規則後件參數。
  12. Gottsch jd. liu sh, minkovitz jb. et al. autoimmunity to a cornea - associated stromal antigen in patients with mooren ' s ulcer. invest ophthalmol vis sci, 1995, 36 : 1541

    王錚.陳家祺，陳龍山，等.板層角膜移植聯合環孢黴素a滴眼治療蠶蝕性角膜潰瘍.中國實用眼科雜志， 1996 ， 14 : 283
  13. A dot - ppa - elisa has been developed to detect the specific antibody against streptococcus suis. the antigen was isolated from group c d e r and type 2 streptococcus suis by three different method : ( a ) autoclave extraction method, ( b ) hcl - extraction method, and ( c ) fuller ' s method

    本研究選取c 、 d 、 e 、 r群及2型鏈球菌標準菌株，以高壓法提取抗原建立了檢測豬鏈球菌病血清抗體的dot - ppa - elisa方法。
  14. Cea is probably the most extensively characterized human tumor associated antigen. it was discovered in colorectal and pancreatic carcinomas in 1965 and it " s full cdna was cloned in 1987. it is a kind of glycoprotein and it " s molecular weight is 180kd

    癌胚抗原（ carcinoembryonicantigencea ）是一種最常見的腫瘤相關抗原（ taa ） ，也是國際上公認的腫瘤標志物，於1965年首次在人結腸癌和胰腺癌中發現， 1987年克隆出它的全長基因序列。
  15. The hbaf53 fragment obtained was used as antigens to immunize a rabbit. in the first immunization, equal volume of freund " s complete adjuvant was mixed with antigen solution to enhance the antigenicity

    用獲得的抗原免疫實驗動物，首次免疫添加等體積的弗氏完全佐劑，以增強抗原的免疫原性。
  16. Macrophage is a kind of immune cell as well as accessory cell. it can function as antiinfection, anticancer, immune response and immunoregulation by phagocytosis, antigen presentation, cytokines secretion, lymphocyte activation, reactive oxygen and no production. it ' s an important part of body immune system

    巨噬細胞（ macrophage ）既是免疫細胞，又是輔佐免疫應答細胞，可通過吞噬、抗原呈遞、分泌細胞因子、激活淋巴細胞和產生活性氧、 no等作用而行使抗感染、抗腫瘤、免疫應答和免疫調節作用，是機體免疫系統的重要組成部分。
  17. A 12 bp sequence of the 5 " end from the polyhedrin protein gene of bmnpv was ligated to the 5 ' end of hbsag ( pres2 + s ) protein coding sequence by pcr. the fusion product coding for hbv surface antigen medium sized ( hbmp ) with 4 - additional aa of bmnpv polyhedrin protein was obtained

    本研究通過pcr突變的方法，在hbsag （ pres2 + s ）前s2序列的5 』端融合了bmnpv多角體蛋白基因5 』端的12個堿基，獲得了融合乙肝表面抗原中蛋白基因（ hbmp ） 。
  18. Molecular recognition is utilized to describe the molecular binding process in a specific manner. it ' s well known that the antibody / antigen, receptoraigand and enzyme / substrate are the three molecular recognition models in animate bodies

    分子識別是分子間專一性的結合過程，抗體與抗原、受體與配體、酶與底物是人們所熟悉的生物體內的分子識別的三個模型。
  19. Fortunately, recently widely used bispecific antibody technique provided us a good model for target rca blocking for it ' s dual antigen binding activity and for the availablity of high

    為了進一步探討用基因工程的方法制備抗病毒雙特異性抗體的可能性，我們又在現有的條件下構建、表達了
  20. It is that recombinant plasmid which contain a protective antigen gene was rejected into animal ' s muscle, then the protein that the recombinant plasmid expressed in vivo will directly induce immune response in the body

    該技術將含有外源蛋白編碼序列的質粒dna注入某種動物，外源蛋白可以在體內直接表達並持續刺激機體產生免疫應答。
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