suppressor factor 中文意思是什麼

suppressor factor 解釋
抑制劑
  • suppressor : n. 鎮壓者;隱蔽者;禁止者;刪除者;抑制因子;【物理學】消聲器;【無線電】抑制柵極。
  • factor : n 1 〈英國〉經銷人;(代客買賣收取傭金的)經紀人;代理商;代辦人;〈蘇格蘭語〉 土地經管人。2 要素...
  1. The two single - pass transmembrane proteins, delta and serrate, have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway. rbp - j, the mammalian homolog of su ( h ), recognizes the core sequence ( c / tgtgggaa ) of dna

    Rbp - j是果蠅促神經發生基因su ( h ) ( suppressorofhairless )在哺乳動物的同源物,它通過其識別序列( c tgtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。
  2. Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription

    當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后,就與ajs發生解離而游離到細胞漿中,此時細胞的粘附功能也發生障礙,游離到胞漿中的-連環蛋白,一部分被抑癌因子apc降解,一部分則轉移到細胞核內,與核內的轉錄因子tcf lef結合,啟動與細胞增殖有關的基因轉錄。
  3. Delta, jagged and serrate have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway

    Rbp - j是果蠅促神經發生基因su ( h ) ( suppressorofhairless )在第四軍醫大學碩士研究生論文哺乳動物的同源物。
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