transmembrane 中文意思是什麼

transmembrane 解釋
橫跨膜的
  1. For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development

    如g蛋白偶聯受體通過g蛋白介導產生胞內信使( camp , cgmp , dg , ip _ 3 )將胞外信號傳遞到胞內,從而引起生物學效應;內質網上也存在著一些跨膜蛋白,其中一些與蛋白質的合成及運輸有關,一些與物質代謝有關,如葡萄糖- 6 -磷酸酶。
  2. The two single - pass transmembrane proteins, delta and serrate, have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway. rbp - j, the mammalian homolog of su ( h ), recognizes the core sequence ( c / tgtgggaa ) of dna

    Rbp - j是果蠅促神經發生基因su ( h ) ( suppressorofhairless )在哺乳動物的同源物,它通過其識別序列( c tgtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。
  3. Main methods and results are as followed : 1 epitope analysis of agonist - binding region of nrla physicochemical properties and antigenicity of two agonist - binding regions of nrla were analyzed through bioinformatics : domain p1 containing 151 amino acid residues preceding the first transmembrane domain of the human nrla, domain p2 with 144 residues following the third transmembrane domain. four parameters including hopp - woods and kyte hydrophilicityjanin accessibility, karplus - schulz flexibility, and welling antigenicity were used to determine the antigenic sites, and prosite programme and chou - fasman method were employed to analyze their related sequence motif and the secondary structures

    用goldkey軟體分別選取公認的hopp等與kyte等親水性參數、 jain表面可及性參數、 karplus - schulz主鏈柔韌性參數及welling抗原性參數對p1 、 p2兩個多肽片段進行參數分析。並採用通用的prosite程序與chou - fasman方法比較分析p1 、 p2多肽片段的氨基酸位點與二級結構特徵。綜合判定兩個多肽片段的抗原性及其位點,結果認為p2抗原性強于p1 。
  4. Almost one - third of all proteases can be classified as serine proteases, including complement subcomponent clr / cls, mannose - associated serine proteases ( masps ), ovochymase, spermadhesin, type ii transmembrane serine proteases ( ttsps ) etc. these proteins are involved in diverse biological processes, including developmental processes such as complement activation, ovulation, fertilization, tissue remodeling, cellular migration, cancer invasion and metastasis, intestinal digestion, embryogenesis, or organogenesis

    絲氨酸蛋白酶( serineprotease )是機體最重要的酶分子之一,約占機體蛋白酶的三分之一,我們較熟知的絲氨酸蛋白酶就包括補體組分c1r c1s 、甘露糖結合絲氨酸蛋白酶、 ovochymase 、 spermadhesin和型跨膜絲氨酸蛋白酶等,它們參與了補體活化、排卵、授精、組織重建、細胞遷移、腫瘤浸潤和轉移、消化、胚胎發育、器官形成等多項生理功能。
  5. The predicted secondary structure of the protein displays multiple putative transmembrane domains

    1 。計算機軟體分析表明,其編碼的蛋白具有多次跨膜樣結構域。
  6. Furthermore, the growth of escherichia coli tg1 and staphyloccus aureur atcc25923 were not under the influence of apss. the switching pulse induced a perceptible sustained transmembrane current on the planar lipid bilayer after unpurified aps added

    機理研究表明未經純化的aps作用於脂質平面膜,可以形成跨膜電流,提示活性成分可能通過改變脂質雙層膜通透性抗菌。
  7. The env protein deduced from env gene encodes the hydrophilic surface protein ( su ) and the hydrophobic transmembrane domain ( tm ) that determine the specific interaction between virus particles and cell surface receptors during retroviral entry. the su of retroviruses is a highly variable genetic element, containing receptor binding sites and major antigenic determinants. exjsrv - specific dna probes were derived. by using these dna probes in tissue hybridization. we successfully identified jsrv mrna expression and proviruses dna in sheep lung tissues infected with jsrv and control group has no postive signals, validating the use of exogenous virus - specific dna probes in the analysis of oncogenic proviral integration sites and identification of integrated exogenous proviral sequences

    用地高辛隨機引物法標記exjsrv特異的env片段,制備探針,原位雜交檢測spa肺組織中的rna及前病毒dna ,結果表明spa患羊肺組織內有jsrvenv基因mrna的表達,同時也檢測到了前病毒dna ,而相應的陰性對照卻無陽性信號,證實外源性病毒特異的dna探針在致瘤性前病毒的整合位點和整合的外源性前病毒的檢測中具有可信度。
  8. We fused the gfp into the c - terminal region as well as n - terminal region of emt - 1 protein. the result showed that the localization of the protein encoded by the full length emt - 1 cdna was in endoplastic reticulum ( er ). extracellular region, transmembrane and intracellular region showed the similar cellular localization

    我們用綠色熒光蛋白融合於emt l全長及其不同截斷形式的梭基和氨基端,瞬時轉染cos 7細胞,通過熒光顯微鏡觀察,發現emt l編碼的蛋白呈現內質網定位的特點。
  9. The deduced amino acid sequence had two strong transmembrane helices, i. e., the first from position 5 ( gly ) to position 35 ( val ) and the second from position 28 ( ala ) to position 46 ( leu )

    推測的氨基酸序列具有兩個顯著的跨膜螺旋:第一個螺旋位於第5個( gly和第35個仰)氨基酸之間,第二個螺旋位於第28 ( alg和第46隊eul個氨基酸之間。
  10. The transmembrane activity of the ptd of tat protein fused at the carboxyl - terminus of gfp in vivo

    端融合在活體體內的跨膜遞送作用
  11. To investigate the secondary structure of this gene, we found it has a transmembrane region near the n - terminus, followed by a proline - rich conserved region, and it has a conserved haemachrome binding region about 60 aa away from carboxyl terminus

    分析氨基酸序列的二級結構發現基因n -端具有跨膜的疏水序列,其後具有富含脯氨酸保守區,在距離羧基端60個氨基酸處具有高度保守的血紅素結合域。
  12. A transmembrane function of microtubules has to be considered.

    必須考慮微管橫跨膜的功能。
  13. G - protein - coupled seven - transmembrane receptor

    七次跨膜g蛋白耦聯受體
  14. Our previous work verified that heterotrimeric g protein was involved in regulation of pollen germination, tube growth and in the transmembrane mechanism of extracellular cam signal. in the present study, we provide further evidence that plc signaling pathway was presented in lily pollen and involved in extracellular cam signal transduction mechanism in pollen by molecular, biochemical and physiological approaches. these evidence included : the pip _ ( 2 ) - dependent plc activity was also detected in purified lily pollen protoplasts

    為了給上述信號轉導過程提供進一步的證據,本文以百合花粉為材料,從plc活性的測定、 plc基因的克隆及其與花粉萌發的關系、以及plc活性被g蛋白和cam調控等方面,為肌醇磷脂系統參與花粉萌發和細胞外鈣調素的信號轉導過程進一步提供了分子生物學和生物化學的證據。
  15. Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis

    在上皮細胞內,連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白( e - cadherin )的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白( -連環蛋白) - -連環蛋白組成的粘附連接體( adherensjunctions , ajs ) ,這種復合體對維持細胞正常的粘附功能是必需的。
  16. It is divided to extracellular and intracellular part by transmembrane domain. there are 13 n - glycosylation sites, 20 protein kinase c phosphorylation sites, 28 casein kinase ii phosphorylation sites, 4 tyrosine kinase phosphorylation sites and 15 n - myristoylation sites in the extracellular part of bt - r3 protein. an integrin recognition sequences rod lies in intracellular part of bt - r3 protein

    跨膜區域( tmd )將它分為胞內和胞外兩個部分,它的胞外有13個潛在的糖基化位點, 20個蛋白激酶c的磷酸化位點, 28個酪蛋白激酶的磷酸化位點, 4個酪氨酸酶的磷酸化位點, 15個豆蔻(十四烷基)酰化位點;它的胞內有1個整合蛋白( integrin )識別位點。
  17. The transport of water across some cell plasma membranes is facilitated by aquaporin ( aqp ) water channels, which are small transmembrane proteins that function as passive conduits for osmotically or hydrostatically - driven water transport

    水通道蛋白( aquaporin , aqp )是一種小分子跨膜蛋白質,其在滲透壓和靜水壓的驅動下能促進水分子跨細胞膜轉運。
  18. There are still many questions remain unanswered, including the mechanisms that specify oligochitosan recognition, the participation of additional molecules in transmembrane signaling, and the repertoire of downstream pathways activated by oligochitosan. it was also observed that pdtc did not totally block no production, which gave us another evidence that there must be some other signal transduction pathways ( perhaps mapk, pkc, ca2 + dependent signaling ) involved in the activation, so further investigation is necessary to clarify molecular mechanism of oligochitosan inducing immunological en

    Westemblot結果顯示100林歲ml劑量的殼寡糖作用於raw264 . 7細胞( 4x105個細胞/ ml ) 4h ,胞核內p65的含量明顯增加, 6h時達到高峰, 10h時恢復到基礎表達量,這就提示在殼寡糖對巨噬細胞的激活過程中nf一kb活化狀態可以持續6個小時。
  19. Hydrophobicity analysis suggested that the v - h + - atpase subunit c from 5. salsa was a transmembrane protein with four transmembrane domains. earlier experiments indicated the conserve glutamyl residue in the fourth transmembrane domains might participate in the proton translocating across the membranes

    鹽地堿蓬液泡膜h ~ + - atpasec亞基第四個跨膜區存在高度保守的谷氨酸殘基,先前的研究表明此谷氨酸殘基可能與h ~ +跨脂雙層運輸有關。
  20. The single peptide of bt - r3 protein is a a helix which orients from inside to outside, and the transmembrane domain is also a helix which orients from outside to inside

    Bt - r3受體蛋白最前端的信號肽是一個由內向外a螺旋,跨膜區域( tmd )是一個由外向內的a螺旋。
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