Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment
用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶
多酚的細胞毒性及其對耐藥性的逆轉作用,並與pgp抑制劑
奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平, mcf - 7 adr呈強陽性,而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % , mcf - 7細胞系細胞陽性率為1 . 8 % 。
Our second day began early with a flight to quito
第二天一早,我們乘飛機前往
奎多。
Three or four days uniess we get you more quinine
3到4天,除非我們幫你弄到更
多奎寧
The two main avatars of vishnu that appear in the epics are rama, the hero of the ramayana, and krishna, the advisor of the pandavas in the mahabharata
兩個主要的毗瑟奴化身都出現在羅摩的史詩里,羅摩衍那的英雄;還有《摩河婆羅
多》的般度族顧問
奎師那。
The paratroopers, armed with exercise rifles that shoot rubber bullets, landed in a corn field outside the fremont correctional institute, colorado department of corrections spokeswoman katherine sanguinetti said
科羅拉
多懲教部女發言人凱薩琳桑
奎內提指出,這批天兵配備發射塑膠子彈的演習用步槍,降落在弗雷蒙特懲教所外的一個玉米田。
Inheriting the philosophical tradition of mediaeval scholasticism, thomas aquinas constructed a systematic rational ( natural ) theology on the foundation which totally combined aristotle ' s philosophy and augustine ' s theology
摘要托馬斯?阿
奎那秉承中世紀經院哲學傳統,在全面整合亞里士
多德哲學和奧古斯丁神學的基礎上,建構起了一個系統化的理性神學體系。
The study on the replaced reaction of coordination water in transition elements heteropoly anions with keggin structure by quinine
結構過渡金屬雜
多陰離子中配位水與
奎寧的取代反應
Chloroquine, and other basic drugs and dyes are accumulated very considerably.
氯
奎、其它堿性藥劑以及染料,積聚得相當
多。
Palermo, who brought back former coach francesco guidolin on monday, are most in danger of dropping out of the three uefa cup spots
巴勒莫,他們在周一請回了前任主教練弗朗切斯科?
奎多林,堅難的爭取為數不
多的三個聯盟杯席位。
The ironforge exchange of qeynos has taken advantage of the recent bell, broker, banker and mender additions to qeynos to acquire the struggling business of fhara ' s furnishings in north qeynos, and has refurbished this building to be their new headquarters
鐵煅交易所因為新增加的水手之鐘、中介商、銀行以及修理工,為工匠們提供了更
多的便利,並且將店面重新翻修,在與北
奎的法拉家居的商業競爭中實力大增。
"what a pretty little nell!" cried quilp.
「
多麼標致的小耐兒啊!」
奎爾普叫道。
Viewed from this angle, we find that in the theory of thomas aquinas, a representative figure of medieval philosophy, belief and reason are two interrelated and interpenetrated constituent elements, which are connected with each other intrinsically and necessarily, rather than two independent systems that were mixed together occasionally and unnecessarily
從這種角度看問題,我們發現,在中世紀哲學的集大成者
多瑪斯?阿
奎那的思想體系中,信仰與理性並不是兩種截然不同的思維方式,神學與哲學也不是兩個被無原則地摻和在一起的理論體系,而是兩個相互滲透和相互作用的、有著必然的內在聯系的構成要素。
The theory basis for medium frequency receive includes sample theory, the signal ' s orthodoxy transform theory, multi - rate digital signal processing theory and signal ' s modulation and demodulation theory
中頻數字接收的理論基礎是信號的奈
奎斯特采樣定理或帶通采樣定理,信號的正交變換原理,
多采樣率數字信號處理原理以及信號的調制解調理論。
Lord krsna said : many births of mine and also of yours have passed o arjuna ; i am knowledgeable of all of them ; but you are not knowing
主
奎師那說:阿諸那啊,你我都經歷了許
多世啊;我對前生諸世一清二楚,而你卻一無所知。
John quincy adams was strong - willed and stubborn, and many people felt that he was even harder to like than his father
約翰?
奎因斯?亞當總統是個意志堅強且頑固的人,很
多人認為,他比他父親更加令人難以接受。
Kratos : do you see, gods of olympus ! ? do you need more proof than this !
奎托斯:看見了么?奧林巴斯山的眾神,你們還需要比這更
多的證明么!
The lincoln bedroom has been redecorated several times in the last 50 years, most notably by jackie kennedy
在過去50年,林肯臥室曾經經歷了數次重裝修,而大多數重裝修都發生在傑奎琳?肯尼迪擔任美國第一夫人期間。