新抗原 的英文怎麼說

中文拼音 [xīnkàngyuán]
新抗原 英文
neoantigen
  • 新 : Ⅰ形容詞1 （剛出現的或剛經驗到的） new; fresh; novel; up to date 2 （沒有用過的） unused; new 3 （...
  • 抗 : Ⅰ動詞1 （抵抗; 抵擋） resist; combat; fight 2 （拒絕; 抗拒） refuse; defy 3 （對等） contend with...
  • 原 : Ⅰ形容詞1 （最初的; 原來的） primary; original; former 2 （沒有加工的） unprocessed; raw Ⅱ動詞（原...
  1. In view of the common property of dendritic cells and complement, namely their ability to link innate and acquired immunity, and with no reports, to date, addressing the direct effects of complement on the biological functions of dendritic cells, we decided to study the interaction between the complement system and dendritic cells

    本研究的完成有助於在免疫應答的調控機制方面獲得新的認識，並對補體和dc在連接天然免疫和獲得性免疫之間的作用及相互關系能有更全面的理解，為進一步從新的角度和思路深入研究dc在抗原特異性免疫應答與免疫耐受中的作用及其機制奠定基礎。
  2. The chief offending antigen in haemolytic disease of the newborn is antigen d of the rhesus series.

    新生兒溶血病起主要作用的抗原是RH系列的抗原D。
  3. Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants

    血吸蟲病疫苗研究已有60多年的歷史，大致經歷了死疫苗、活疫苗（照射致弱尾蚴疫苗）和基因工程疫苗等研究階段，產生了一些who / tdr推薦認為很有希望的疫苗候選分子，如谷胱甘肽- s -轉移酶（ gst ） 、副肌球蛋白（ sm97 ） 、照射致弱疫苗抗原5 （ irv - 5 ） 、磷酸丙糖異構酶（ tpi ） 、曼氏血吸蟲膜內在蛋白（ sm23 ）和脂肪酸結合蛋白（ fabp ， sm14 ）等，但其對宿主的保護作用均不甚理想，未能穩定地達到40或以上的保護力水平，因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑，進一步提高其保護力。
  4. Female mice serum and vaginal secretion antibodies, their fertility and the pathological changes were determined. on the other hand, the effects of the anti - serum against synthetic peptide on the sperm - egg interaction during ivf and the location of p3 peptide in sperm were watched. the main results and conclusions were as follows : 1 ) the new antigen p3 peptide which harvested from the 430a peptide synthesizer were verified by the mass spectrograph and hplc, that the ratio of mass / charge of the synthetic peptide was equal to the molecular weight in theory and its purity was above 95 %

    本研究的主要結果和結論如下：一、經抗原分子設計，在430a自動肽合成儀上合成的新抗原p3 ，經質譜儀分析證明其荷質比與理論一致；純化后，其純度大於95 ；將新抗原與klh偶連后免疫小鼠，經westernblot證實其誘導的特異性抗體可識別小鼠、大鼠、人睪丸組織中分子量約為22kd和55kd左右的蛋白質。
  5. The chief offending antigen in haemolytic disease of the newborn is antigen d of the rhesus series

    新生兒溶血病起主要作用的抗原是rh系列的抗原d 。
  6. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  7. The results suggested that human hscs can engraft into rat and differentiate into multilineage under certain microenvironment. thus, the human / rat xenograft model may provide a useful and convenient method for assay human hscs in vivo

    新生大鼠免疫系統發育不完善，對異種抗原可形成免疫耐受，是很好的研究異種移植的實驗動物，且經濟。
  8. On the consideration of these problems and the fact that the rat immune system is not fully developed until birth, we tried to transplant neonatal rat with human hscs to test the possibility of this xenograft model

    但此實驗模型操作復雜且實驗周期長，大多數實驗室不具備利用此實驗模型的條件。有研究證明，新生大鼠免疫系統發育不完善，對異種抗原可形成免疫耐受。
  9. The assay procedure is based on the bioreaction of the analyte nd. ab and enzyme labeled hrp - nd. ab competing for the nd. ag sites at the newly regenerated biocomposite surface

    該分析過程的原理是：分析物nd ab與酶標分析物hrp - nd ab在已更新的生物組分表面上，競爭結合抗原（ nd
  10. So gaining vp7 gene and its expressing product is key to the preparaion of the new type vaccine and specific diagnosis anigen

    因此，該基因的克隆及表達，對于制備新型疫苗和特異性診斷抗原具有重要意義。
  11. Stable fluorescent labels bhhct - eu3 +, bpta - tb3 ", and europium nanoparticle were used to develop sandwich - type time - resolved fluoroimmunoassays for hbsag. fluorescence intensity was directly detected on the surface of the solid phase

    利用穩定的稀土標記物bhhct - eu3 + 、 bpta - tb3 +和銪納米顆粒建立夾心型固相時間分辨熒光免疫分析（ trfia ）直接定量測定乙肝表面抗原（ hbsag ）的新方法。
  12. The who classification states that acute lymphocytic leukemia ( all ) should be classified by the pattern of reactivity of cell to a panel of lineage - associated antibodies and, where possible, genetic abnormalities. the expression of cd antigens on leukocytes is currently determined by flow cytimertry, which is expensive and labor - intensive, requiring 5 - 20ul quantities of fluores - cently labeled antibodies and allowing concurrent analysis for a limited number of cd antigens, usually three to four. from clinical point of view, an efficient method is required for analysis of a large number of samples in a single experiment

    我們設計了一種新型的細胞晶元，其原理是充分利用玻片的硬度高，透明性好的特點，應用細胞膜表面不同的抗原物質，與包被在玻片上的不同抗體發生特異性結合，通過一次實驗可以將被測細胞懸液中不同膜表型的細胞分離、固定在同一張玻片的不同特定區域，保持了細胞的完整性及活性，又可通過簡單的操作一次將多細胞懸液進行免疫分群。
  13. Meanwhile, the male mice deficient for germ - cell cyritestin are infertile. therefore, both spl7 and cyritestin are important molecules in the process of fertilization. nevertheless, people can not get fully satisfied the results in some contraceptive researches for their limited effects respectively

    其n端含有去整合素結構域，然而多數實驗結果表明單一應用這些分子所獲得的免疫性避孕效應非常有限，從而提出今後的研究方向是更具抗原性或良好運載體系的新型多價疫苗。
  14. Recovery estimated from the safh4 plant line indicates that 9 ( jl g of pure active scfv can be obtained per gram of fresh leaf material, on a laboratory scale. the production of the scfv antibody proteins in plant root exudates was also addressed. the scfv antibody protein was continuously secreted from the transgenic tobacco roots into a simple hydroponic medium at 630 to 760 ng g - 1 dry weight of root day - 1

    在水培條件下，轉基因煙草根可連續分泌具有活性的重組抗乙肝病毒表面抗原pres1 （ 20 - 47 ）單鏈抗體進入到液體培養液中，不須破壞植物即可連續獲得重組單鏈抗體，為利用植物生物反應器連續生產單鏈抗體開辟了新途徑。
  15. Illuminated by human immune system, this paper presents a continuous learning model for intrusion defense that follows the principle of how bacterin stimulates the immune system to generate antibody. this model presents how to get the important “ bacterin ” to add to the database, which is used to do signature matching and anomaly detection, and thus protect system from unknown intrusion ( virus )

    受到疫苗和人體免疫系統工作方式的啟發，本文提出一種入侵預防系統模型，它模擬人體注射疫苗后免疫系統產生相應抗體抵抗抗原的機理:通過設置捕獲器捕獲最新的外部入侵病毒並將其加入病毒特徵庫，通過特徵匹配和異常檢測兩種方式檢測識別病毒並將其隔離消除。
  16. Conclusions : this study opened a new field of application of antigen - pulsed dcs for prophylactic purposes when adequate levels of protective antibody cannot be induced by traditional vaccination approaches

    結論：該研究開辟了負載抗原的樹狀突細胞、新的、作為預防用的應用領域，當足夠的保護性抗體水平通過傳統的接種方法不能被誘導時。
  17. This bispecific antibody companied with another anti - p24 monospecific monoclonal antibody can build a new way of indirect rbc agglutination to detect p24 antigen, and this new way is preliminarily applied to detect serial diluted p24 to determine the sensitivity

    用雙特異性抗體致敏人a型紅細胞做指示劑，以抗p24單特異件單克隆抗體9a7做交聯劑，建立間接血凝檢測p24抗原的新方法，並初步應用於檢測系列稀釋的p24抗原以確定測定的敏感性。
  18. So piezoelectric immunnosensors is gradually applied to some fields such as biochemical research, clinical analyze, environment and industry process assay. according to different method of immobilized antigens or antibodies, developed some new piezoelectric immunnosensors to determine proteins in consult serum

    湖南大學分析化學碩士論文李丹200年6月本文結合壓電免疫傳感器抗體（抗原）固定化方法的不同，研製了一些新的壓電免疫傳感器用於參考血清中的一些蛋白的測定。
  19. Genetic vaccine is quite different in structure from traditional ones. the experiments show that delivery of genetic material into an animal ' s cells can trigger some synthesiztion of the encoden proteins as well as of antibodies targeted against those proteins

    核酸疫苗是將編碼某種抗原蛋白的外源基因插入某種表達載體中並直接導入的動物體內，表達抗原蛋白，並誘導宿主產生對該抗原蛋白免疫應答的革命性的新型疫苗。
  20. Objectives to improve the effect of a single mtb8. 4 dna vaccine, we constructed a chimeric mtb8. 4 / hil - 12 eukaryotic plasmid by linkage of mycobacterium tuberculosis mtb8. 4 gene to human il12 gene with a simple linker ( gly4 - ser ) 3. we analyzed the immunogenicity of chimeric dna vaccine and investigated the immune responses elicited when mtb8. 4 / hil12 was presented as endogenous ag

    目的：以il - 12作為分子佐劑，與結核桿菌新抗原mtb8 . 4基因連接形成嵌合分子，將其克隆到真核表達質粒中，構建成嵌合dna疫苗，研究其在小鼠體內誘導細胞免疫應答的效果及對c57bl 6n小鼠的免疫保護作用，為尋求安全、有效、廉價的結核病新疫苗打下基礎。
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