核酸生物化學 的英文怎麼說

中文拼音 [hésuānshēngwùhuàxué]
核酸生物化學 英文
biochemistry of nucleic acids
  • 核 : 核構詞成分。
  • 酸 : 酸構詞成分。
  • 生 : Ⅰ動詞1 （生育; 生殖） give birth to; bear 2 （出生） be born 3 （生長） grow 4 （生存; 活） live;...
  • 物 : 名詞1 （東西） thing; matter; object 2 （指自己以外的人或與己相對的環境） other people; the outsi...
  • 學 : Ⅰ動詞1 （學習） study; learn 2 （模仿） imitate; mimic Ⅱ名詞1 （學問） learning; knowledge 2 （學...
  • 核酸 : [生物化學] nuclein; nucleic acid核酸聚合酶 nucleic acid polymerase; 核酸酶 nuclease; 核酸內切酶 [生物化學] endonuclease
  • 生物 : living things; living beings; organisms; bios （pl bioi bioses）; biont; thing; life生物材料 biol...
  1. Degenerate oligonucleotides to highly conserved regions of cucumis melo 1 - aminocyclopropane - 1 - carboxylic acid ( acc ) oxidase gene were used to prime the amplification of fragment of 128bp by ploymerase chain reaction ( pcr ) in samples of genomic dna from fruit of cucumis melo l. cv hetao flesh, which was cloned into plasmid vector pmd - 18 - t. the clon of antisense orientation were selected, and it was inserted downstream of camv35s promoter and enhancer " " of tmv into the plant expression vector pbinyxw, antisence expression vector pbinya was constructed. at the base that pollination and fertilization of cucumis melo l. cv hetao was studied, using pollen tube pathway transformate cucumis melo l. cv hetao, 76 fruit had been obtained, moreover, hardness and content of sugar were analysed

    本實驗以河套蜜瓜果肉基因組dna為模板，用甜瓜acc氧化酶基因特異寡核苷酸鏈為引物進行pcr擴增，得到128bp的擴增產物。將得到的擴增產物克隆到質粒載體pmd - 18 - t上，篩選反向克隆，然後將其反向構建到植物表達載體pbinyxw的camv35s啟動子和tmv增強子「 」的下游，構建成反義表達載體pbinya 。並在對河套蜜瓜授粉受精生物學研究的基礎上，通過花粉管通道法轉化河套蜜瓜，共獲76顆瓜，並進行了硬度和含糖量的分析。
  2. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  3. With the rapid development of molecular biology, the researchers of different scientific background are provided with a good opportunity to enter the field. people can resolve some important difficult problems with all kinds of research methods and knowledge in their fields. it is chemists " tribute that they design and synthesize effective nucleic acid cleavage reagents and clarify the reaction mechanism of complexes and dna, which makes it possible to search effective remedial reagents and structural probes by molecular design

    分子生物學的迅猛發展為不同科學背景的研究者涉足該領域提供了良好的機遇，人們可以利用各自領域的研究方法和知識來攻克生物學中的一些重要難題，化學家所能做的貢獻就是設計和合成一些特異識別和高效切割的核酸斷裂試劑，並闡明其作用機理，從而使通過分子設計尋找有效的治療試劑和結構探針成為可能。
  4. Such examples are given as the blood filtering principal of hemoglobin, catalysis of enzymes, immune recoglization, prion, glycoprotein and the relationship of structure and function of membrane protein, et al, as well as the applications to medicine

    在簡要介紹結構生物學的研究方法的基礎上，主要從分子水平闡述蛋白質和核酸的結構原理、相互作用、結構與功能的關系，通過具體實例闡述血紅蛋白的輸氧機制、酶的催化機制、免疫分子識別、朊病毒、糖蛋白、生物膜的結構功能關系等，以及結構生物學在醫學上的應用。
  5. From dead chicken which infected infectious stunting syndrom of our province, one virue was isolated using spfeggs, chicken embryo fibroblast, mdck18, and vero cell. this virus was unable to agglutinate chicken erythrocytes. in order to definite the pathogeny of infectious stunting syndrom. physical and chemical specific property, types of the nucleic acid of the isolated virus, recurrent infection and other biological property determination and indirect elisa test proved it as a parvoviruses like strain of chicken

    為確定該病的病原，對所分離病毒進行了理化特性測定、病毒核酸型別測定、動物回歸試驗等生物學特性測定，證明該分離病毒與細小病毒科（ parvovirdae ）細小病毒屬（ parvovirus ）的雞細小病毒（ chickenparvovirus ）特性基本相符，核酸型為dna型。
  6. So must use information theory method depict and abundant the genetic diversity index system. in addition to, the introduce of molecule biology technology and the research of nucleotide sequence evolutive give a new method for population genetic, so must do deeply research about the analysis method of dna sequence data = the research main about the follows : there are three parts about the information model of population genetic : one about the shannon information entropy property of equilibrium population and the entropy change in the process of establish equilibrium ; another research is about the diversity measure - ment of genetic variation ; lastly, research the shannon information measurement about the disequilibrium gene variation. the result is : 1 to a definite gene distribution, the genotype entropy reach the maximum at the equilibrium population, the process of population from disequilibrium to equilibrium, the entropy get large and large

    此外，分子生物技術的介入及核苷酸序列進化的研究都為群體遺傳學的深入研究提供了新的途徑，但關于dna序列數據的分析方法需要作進一步的研究。本研究主要體現在以下幾個方面： （一）關于群體遺傳學的信息論模型研究，主要分為三部分內容：一是群體平衡的shannon信息熵的性質和群體平衡建立的熵變性質；二是群體遺傳多樣性測度的研究；三是非平衡群體的基因變異測量shannon信息量的方法研究。得到了如下結論： 1 、平衡群體的shannon信息熵最大，群體平衡的過程是熵的增大過程。
  7. Research interests : organic synthesis, including synthetic methodology, divergent oriented organic synthesis, asymmetric synthesis, asymmetric synthesis of small molecules with biological significance ( alkaloids, amino acids, pheromones, nucleosides analogues, enzyme inhibitors, receptor agonists and antagonists, bioactive heterocycles etc ) and chiral drugs

    研究興趣：主要從事有機合成化學及相關的化學生物學研究，包括合成方法學、多樣性導向有機合成、不對稱合成、有機小分子調節劑（生物堿，氨基酸，昆蟲信息素，酶抑制劑，受體拮抗劑，核苷類似物等）和手性藥物的不對稱合成。
  8. The percentage of polymorphic sites, degree of genetic polymorphism and genetic distance were compared and the phylogenetic tree was constructed by neighbor - joining method. the partial mitochondrial 16s rrna gene was amplified by polymerase chain reaction ( pcr ) and the pcr products were directly sequenced after purified. these sequences, together with the homologous sequences of another trichiuridae species lepidopus caudatus obtained from genbank were used to analyze nucleotide difference and to establish a upgma phylogenetic tree by means of biological informatics

    汝us價ay1830 ）各12個個體進行rapd分析，對比多態位點比例、遺傳多態度以及遺傳距離，並構建neighbor - join噸系統樹;通過pcr擴增出線粒體165rrna基因，純化后直接測序，利用生物信息學方法進行序列分析和核昔酸變異比較，結合ge紅bar止中大西洋叉尾帶魚（ lepid （護腳caud玫tuseuphrasen1788 ）同源序列構建u甲cm叭系統樹。
  9. And the intron had a lot of gt repeated sequence. the dna and protein sequence of this gene was analyzed using the bioinformatics tools. two functional domains were found in the protein

    運用生物信息學手段對3一磷酸甘油脫氫酶基因核酸以及蛋白質序列做出了分析，發現這個基因編碼兩種功能的結構域，磷酸化酶結構域和3一磷酸甘油脫氫酶結構域。
  10. Hence, in biochemistry, watson and crick ' s discovery of the molecular structure of dna ( deoxyribo - nucleic acid ) is said to be a typical example of pure science

    因此，生物化學領域里沃森和克利克對脫氧核糖核酸分子結構的發現，可以說是純科學的典型例子。
  11. Tissue sections from every animal were double - labeled with the antibodies of map - 2, cox - 2, gdnf, caspase - 3 and either the neuron - specific antibody neuronal nuclear protein ( neun ) or the astroglial - specific marker glial fibrillary acidic protein ( gfap ). we carried out a series of research to explore the effects and mechanism of map - 2, cox - 2, gdnf, caspase - 3 during tbi and trie d to provide some useful theory basis for both the treatment of tbi in the practice and forensic medicine

    並通過上述指標分別與神經元特異性標志物神經元核蛋白（ neuronalnuclearprotein ， neun ）和星形膠質細胞特異標志物膠質纖維酸性蛋白（ glialfibrillaryacidicprotein ， gfap ）進行免疫組織化學雙染色，探討腦損傷后神經元及神經膠質細胞反應性變化情況及其分子生物學機制，以期為腦損傷研究提供有益的數據材料，也為以上指標在法醫學實際檢案的應用提供必需理論依據。
  12. But such thinking may soon have to be radically revised, as high - speed computation moves beyond chips and machines to include the tools of biochemistry and genetics : test tubes, slides, solutions, even dna

    但是隨著高速運算超越晶元和機器的局限將試管、承物玻璃片、溶液甚至脫氧核糖核酸（ dna ）等生物化學和遺傳學工具包括在內，這種想法可能很快就要做出根本性的修正了。
  13. Lingzhi contains various amino acids, micro elements as well as over 100 chemical components such as lingzhi amylose, three - terpene compounds, nucleotide, biological alkali and enzyme

    現代醫學證明：靈芝含有豐富的蛋白質、核酸、脂類、維生素、三萜類化合物、有機鹽類和20多種微量元素，能夠調節、增強人體免疫力，還具有抗疲勞，美容養顏，延緩衰老等功效。
  14. Pharmacogenomics combines traditional pharmaceutical sciences such as biochemistry with annotated knowledge of genes, proteins, and single nucleotide polymorphisms

    藥物基因組學結合了傳統藥學理論（如生物化學）和已經定義了的基因、蛋白質和單核苷酸多態性等各類學科的研究成果。
  15. The mechanism is that the introduced complementary oligonucleotides can bind to the corresponding mrna or double - stranded dna in genome and form partial double - stranded molecules or triple - stranded nucleic acid molecules by sequence - specific and nonsequence - specific antisense action, thus the target gene will be orientationally blocked and expression of the target inhibited so that therapeutic effect could be attained. in this study, we designed a fragment of human c ii ta cdna in antisense orientation using mrna of c ii ta as template. the primers were designed based on 94 - 500 nucleotides segment in 5 " end of ciita gene so that the interested gene contained 407 base pairs which included two aug codons in 1 16 and 188 nucleotides as well as the splicing site between the first and the second exons

    本研究設計以c tamrna為模板的反義cdna片段，從c ta基因5 』端第94位到500位核苷酸段設計引物，目的片段407bp ，覆蓋第116和188位兩個aug密碼子，也包含了第一外顯子和第二外顯子間的剪接位點：用常規分子生物學方法構建了反義片段的腺病毒表達載體（ padeasy - 1系統） ；腺病毒載體經hek293細胞包裝產生含反義片段的重組腺病毒，用氯化銫密度梯度離心法獲得純化的高滴度腺病毒；進行體外基因轉移，分別用反義片段真核表達載體轉染p388d1細胞和用重組腺病毒感染hela細胞，觀察導入的c ta基因反義rna抑制細胞內組成型或誘導型c ta基因表達的作用，從而達到調控mhc -類分子表達的目的。
  16. The origin of life remains very much a mystery, but biochemists have learned about how primitive nucleic acids, amino acids and other building blocks of life could have formed and organized themselves into self - replicating, self - sustaining units, laying the foundation for cellular biochemistry

    生命起源仍然是個謎，但是生物化學家已經知道原始核酸、胺基酸與其他生命建材大概是怎樣形成的，以及它們如何組織成能夠復制自己、又能自謀生存的單位，這些知識奠定了細胞生物化學的基礎。
  17. Topic include : basic chemical knowledge related to life science, origin of life - essential elements, water and proteins, growing up food, nutrients and hormones, messing up narcotics and some stimulant drugs e. g. ketamine and ecstasy, aging and dying medication, chemicals against diseases and the mystery of heredity nucleic acid and the double helix

    內容包括：基本化學概念、生命的起源必需的元素，水及蛋白質、生命的成長食物、營養及荷爾蒙、生命的糟韃毒品及軟性藥物（如k -仔，搖頭丸）的化學成分、衰老與死亡藥物治療及生命的延續及遺傳的奧秘核酸及雙螺旋結構模型。
  18. A review of the applications and prospects of capillary electrophoresis with electrochemical detection to the analysis of biomolecules such as amino acids, protein, dna and hydrocarbon covering, the years from 1994 to 2004, was presented in this paper with 55 references cited

    摘要對近年來毛細管電泳電化學檢測在生物分子（氨基酸、蛋白質、脫氧核糖核酸和糖等）分析中的應用進展作出綜述，展望了電化學檢測在毛細管電泳中的應用前景（引用文獻55篇） 。
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