核酸變性 的英文怎麼說

中文拼音 [hésuānbiànxìng]
核酸變性 英文
nucleic acid denaturation
  • 核 : 核構詞成分。
  • 酸 : 酸構詞成分。
  • 性 : Ⅰ名詞1 （性格） nature; character; disposition 2 （性能; 性質） property; quality 3 （性別） sex ...
  • 核酸 : [生物化學] nuclein; nucleic acid核酸聚合酶 nucleic acid polymerase; 核酸酶 nuclease; 核酸內切酶 [生物化學] endonuclease
  1. Detection of fibroblast growth factor receptor 3 gene mutation at nucleotide 1138 site in congenital achondroplasia patients

    先天性軟骨發育不全成纖維細胞生長因子受體3基因1138位核苷酸點突變的檢測
  2. A microdialysis study of excitatory amino acid levels of the monkey s caudate nucleus during the delayed go no - go task

    延緩go no - go任務操作中猴尾核興奮性氨基酸水平變化的微透析研究
  3. The inclusion bodies of recombinant protein were purified with washing buffer consisting of various urea ( 2mol / l and 4mol / l ) for several times, and then dissolve the fusion protein in the denature buffer using 8mol / l urea as denaturant

    用含有2mol l和4mol l尿素的包涵體洗滌液洗滌包涵體，在37條件下，洗去了大部分菌體蛋白及其它核酸物質。用8mol l尿素作為變性劑溶解包涵體，包涵體在8mol l尿素中的溶解性非常好。
  4. We found nuclear deformation lymphocytes with increased heterochromatin and impaired thymus epithelium cells with increased lysosomes and deformation of mitochondrias. ( 4 ) effects on mouse liver of so2 challenge : so2 can cause significant liver injury. he staining showed several kinds of necrosis of liver including spot necrosis, focal necrosis and submassive necrosis infiltrated with lymphocytes, monocytes, few neutrophils and eosinophils ; tem observation showed fatty degeneration with dispersion of fatty droplets and dilation of rough endoplasmic reticulums, acid degeneration with significant hyperplasia of mitochondrias, necrosis of hepatocytes with karyorrhexis and other organelles losing their normal structure

    （ 4 ）二氧化硫染毒對小鼠肝臟的組織學結構有明顯影響，可引起肝臟點狀壞死、灶狀壞死甚至片狀壞死，伴隨不同程度的炎性細胞浸潤；透射電鏡觀察發現二氧化硫可引起肝細胞脂肪變性、嗜酸性顆粒變和壞死，脂肪變肝細胞中可見大小不等的脂滴存在，嗜酸性顆粒變肝細胞中可見線粒體明顯增生，壞死肝細胞可見細胞核結構破壞，細胞器減少，細胞膜不完整。
  5. With the increase of concentration of aqueous extract from peganum multisectum increased, root vigor, the contents of chlorophyll, soluble protein and nucleic acid in roots and shoots of alfalfa seedlings decreased, while the activities of protease and nuclease, the contents of o2 ( superscript - ), h2o2 and malondiadehyde ( mda ) increased, the activities of superoxide dismutase ( sod ), catalase ( cat ) and peroxidase ( pod ) first increased and then decreased

    幼苗根系活力和葉綠素、可溶性蛋白質、核酸含量隨水浸液濃度的提高而降低，蛋白酶和核糖核酸酶活性及超氧陰離子（ o2 （上標- ） ） 、 h2o2和丙二醛（ mda ）含量則增加，超氧化物歧化酶（ sod ） 、過氧化氫酶（ cat ）和過氧化物酶（ pod ）活性呈先升后降變化。
  6. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  7. Results show that vp37 protein can bind single strand nucleic acid cooperatively and nonspecificallty, and the vp37 - ssrna complex was stable at high salt concentrations, suggesting vp37 is a possible mp. vp37 is the only protein characterized so far showing rna - binding ability in genus fabavirus

    為了驗證vp37是否具有核酸結合能力，我們利用6his - vp37蛋白進行了核酸結合實驗，結果表明vp37是一種能非特異性結合單鏈核酸的蛋白；其在結合核酸時具有協同性； na ~ +的變化對其核酸結合能力影響較小。
  8. So must use information theory method depict and abundant the genetic diversity index system. in addition to, the introduce of molecule biology technology and the research of nucleotide sequence evolutive give a new method for population genetic, so must do deeply research about the analysis method of dna sequence data = the research main about the follows : there are three parts about the information model of population genetic : one about the shannon information entropy property of equilibrium population and the entropy change in the process of establish equilibrium ; another research is about the diversity measure - ment of genetic variation ; lastly, research the shannon information measurement about the disequilibrium gene variation. the result is : 1 to a definite gene distribution, the genotype entropy reach the maximum at the equilibrium population, the process of population from disequilibrium to equilibrium, the entropy get large and large

    此外，分子生物技術的介入及核苷酸序列進化的研究都為群體遺傳學的深入研究提供了新的途徑，但關于dna序列數據的分析方法需要作進一步的研究。本研究主要體現在以下幾個方面： （一）關于群體遺傳學的信息論模型研究，主要分為三部分內容：一是群體平衡的shannon信息熵的性質和群體平衡建立的熵變性質；二是群體遺傳多樣性測度的研究；三是非平衡群體的基因變異測量shannon信息量的方法研究。得到了如下結論： 1 、平衡群體的shannon信息熵最大，群體平衡的過程是熵的增大過程。
  9. The nucleotide ( nt ) sequence of the insert in phz1754 is 2299bps in size. computer assisted analysis of the sequence revealed an open reading frame ( orf ) with a g + c content of 70. 3 % that would encode a protein of 552 amino acids ( aa ). the nt seque nce comparision revealed that the orf in the sequenced region exhibits 85 % dna sequence homology with the cholesterol oxidase gene choa of streptomyces sp

    對phz1754進行外切核酸酶（ exonuclease ， exo ）順序缺失，獲得單向長度漸減重疊的系列突變體，核苷酸序列測定顯示出該ecor - sal片段的精確大小為2299bps ， frameplot程序分析揭示出該區域一個完整的開放閱讀框（ orf ）的存在，其大小為1656bps ， g + c含量為70 . 3 ，編碼552個氨基酸，利用blastsearch程序將orf的核苷酸序列及推導的氨基酸序列與因特網上基因及蛋白質數據庫進行綜合比較，發現無論在核苷酸水平還是在蛋白水平上，該orf均與膽固醇氧化酶表現出同源性，而且與鏈黴菌膽固醇氧化酶同源性最高，說明該orf編碼膽固醇氧化酶基因。
  10. 5. the mpcr - rflp assay was useful for its reliability in monitoring hbv ymdd mutants. melting curve assay and pcr microplate hybridization - elisa assay should be further improved to increase their sensitivity and specialty

    5 . mpcr一rflp法檢測ymdd突變株具有較好的可靠性和可行性，是監測拉米夫定耐藥株的一種非常有效的方法;熔解曲線法和pcr微板核酸雜交法需要進一步完善以提高敏感性和特異性。
  11. Histologically, diffuse distribution of eosinopholic cardiocytes with pyknosis was noted. immunohistochemical staining for myoglobin discovered wide and diffuse loss of myoglobin throughout the ventricular myocardium. ultrastructurally, the myocardial cell with myoglobin loss were characterized by the presence of swollen mitochondria and packed cellular constituents

    組織學檢查注意到彌散性分佈伴有核碎裂的嗜酸性變性，肌紅蛋白組化染色發現整個心室肌廣泛性脫失，超微結構研究表明脫失肌紅蛋白的心肌細胞存在線粒體腫脹和細胞內成分的堆積。
  12. Hbv genotype was determined by the restriction fragment length polymorphism analysis in patients with chronic hbv infection in 5 cities of fujian province. 2. the sensitivities and specialties of melting curve assay and pcr microplate hybridization - elisa assay were compared with mpcr - rflp and sequence analysis for the detection of hbv ymdd mutants in 44 serums from patients receiving lamivudine monitherapy with viral breakthrough

    應用熔解曲線法和pcr微板核酸雜交- elisa法對44例接受拉米夫定治療過程中出現病毒學反跳時的血清進行ymdd突變株的檢測，並與測序法和mpcr - rflp法比較它們的敏感性、一致性。
  13. Study on the influence on copper metabolism in patients with hepatolenticular degeneration treated by sodium dimercaptosulphonate

    二巰基丙磺酸鈉驅銅治療對肝豆狀核變性銅代謝的影響
  14. Relatively, the new wibdv strains gx8 / 99 had less homology to wibdv reference strain hk46 and other 3 field strains as 96. 8 % - 97. 2 % at dna or aa levels, than the homology among hk46 and 3 strains, strains gx8 / 99 more than 98. 4 % - 98. 6 % at dna or aa levels

    為研究病毒的核酸分子結構與其致病性的關系，本研究選取了在致死率上不同的4個ibdv野毒株，比較了它們的vpz基因高變區共494個堿基序列。
  15. This review focuses on morphological and physiological reactions of fruit tree to water stress. leaf area, root growth and microstructure of leaves and roots were investigated. some physiological and biochemical index of fruit tree leaves and roots under water stress, such as variations of stomatal aperture, photosynthesis, photoinhibition, metabolism of lipoxygenase, content of proline, nuclear acid and endogenous phytohormones, were summarized

    從水分脅迫對果樹葉、根的形態指標及顯微結構，葉片氣孔行為、光合作用、光抑制、活性氧代謝、脂氧合酶代謝、多胺代謝、脯氨酸、核酸代謝、內源激素變化等生理生化方面綜述了近十幾年來的研究成果，為全面研究果樹抗旱機理及進一步制定抗旱措施奠定理論基礎。
  16. The rest mutations in pp38 and pp24 are at random. sequence analysis also shows the first 195 nuclear acids of pp38 and pp24 are the same except for the 81 site ( g / c ), but this mutation does not cause the change of amino acid. we regard this as a genetic marker connecting with geography in the evolution of mdv but not related to isolated time and pathotype of different strain of mdv i

    對pp24基因和pp38基因進行同源性比較分析的結果表明，絕大多數毒株二者的前195個核苷酸完全一致，不同毒株間的第81位核苷酸的差異（ g / c ）並不引起編碼的氨基酸變化，僅僅與地域分佈有關，這很可能是mdv在長期病毒衍化過程中形成的地域性遺傳標志，而與病毒的分離年代及mdv的致病型等因素無關。
  17. Using continuous wavelet transform to analysis the long - range correlation of nucleotide sequences

    連續小波變換法分析核酸序列的長程相關性
  18. An expression vector with fragment 9 in antisense orientation was constructed to block the expression of the relevant gene ( fragment 9 related gene, fnr gene ) in vero cells. interestingly, we found that the nontargeted mutation frequency induced by mnng was increased significantly, implicating that the product of the blocked gene may be involved in the inhibition of nontargeted mutation

    利用反義核酸技術構建含反向插入9號片段的真核細胞表達重組體並轉染細胞，以獲得反義rna阻斷vero細胞中相應基因的表達，發現mn 』 ng誘發的非定標性突變頻率顯著增高，提示被阻斷的相關基因的表達產物可能參與抑制非定標性突變的發生。
  19. The sequence is 451bp in length and shows98 % homologous to isolate gi 1575050 gb u57046. 1 pnu57046 deposited in the gene bank

    18pnl57046 ，對它們的核酸序列相應片段比較，僅具7個堿基突變，二者的同源性達98 ，從而確認是pnrsv 。
  20. Of 48 snps, two influenced blood pressure only in men, while two other snps contributed only in women

    48個單核苷酸變異中，兩個只在男性中對血壓有影響，另兩個只在女性中對血壓有影響。
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