殺細胞效應 的英文怎麼說
中文拼音 [shāxìbāoxiàoyīng]
殺細胞效應
英文
cytocidal effect- 殺 : Ⅰ動詞1 (使失去生命; 弄死) kill; slaughter 2 (戰斗) fight; go into battle 3 (削弱; 消除) wea...
- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 效 : Ⅰ名詞(效果; 功用) effect; efficiency; result Ⅱ動詞1 (仿效) imitate; follow the example of 2 ...
- 應 : 應動詞1 (回答) answer; respond to; echo 2 (滿足要求) comply with; grant 3 (順應; 適應) suit...
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
- 效應 : [物理學] effect; action; influence
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Killing effects of different prodrugs combined with suicide gene hsv - tk on hep - 2 in vitro
自殺基因系統對喉癌細胞體外殺傷效應的比較研究Chemotherapy use chemical drugs to treat tumor, it also bring harm to person ' s body. it is a new hotspot that using ultrasonic to treat tumor in the world recently. focusing ultrasonic on tumor, we can kill the malignant cells using the heat generated by ultrasonic without serious side effect like actinotheraphy or chemotherapy, so, it is new method with great hope
將超聲波用於腫瘤治療是近年來各國研究的熱點,通過將超聲波聚焦到腫瘤組織上,利用其熱效應殺死腫瘤細胞,不會給患者帶來生理痛苦,也不會像放療和化療那樣產生嚴重的副作用,因此是一種很有發展前途的新方法。Inductive effects of six herbicides : acetochlor, saturn, nc - 302d ( + ), frifluralin, sofit and 2 - ethyl - 4chloro sodium hydration, on micronuclei ( mcn ) and other nuclear anomalies ( ona ) in erythrocytes of loach were studied
研究了乙草胺、殺草丹、精禾草克、氟樂靈、掃?特, 2 -甲- 4氯鈉水劑等6種除草劑對泥鰍紅細胞核的誘變效應。Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用, t細胞在發揮抗瘤效應(分泌細胞因子和直接殺傷)之前必須先經過活化,體內專職抗原提呈細胞( apc )細胞並使其活化,樹突狀細胞( dendriticcell , dc )為t細胞的激活提供雙重信號, t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后,通過tcr - cd3復合體傳遞抗原特異性識別信號(第一信號) ,以cd28為主的t細胞表面輔佐分子識別dc表面b7分子,傳遞非特異性協同刺激信號(第二信號) ,在機體抗腫瘤免疫應答中處于核心地位。At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是,學者們發現這一療法存在著如下的缺陷:單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用,且有誘導免疫耐受的潛在危險,有時反而會促進腫瘤的生長;事先需對患者的hla單倍型進行鑒定,以確定ctl表位與hla單倍型是否匹配,目前尚缺乏能與所有hla單倍型相匹配的ctl表位,從而限制了這一療法的應用;這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞,但對腫瘤細胞的殺傷能力較弱:這種l表位抗原肽缺乏cd4汀h細胞相關的表位,因此,不能誘導有效的th細胞免疫應答。In addition to direct killing, activation of the complement system results in the generation of numerous split products, which bind to complement receptors on various cells of the immune system, thereby modulating inflammation and mounting an immune response
補體系統除了補體的直接殺傷機制外,在補體活化過程中釋放的多種小片斷分子具有廣泛的生物學效應,包括趨化中性粒細胞和淋巴細胞、調理吞噬、參與調節細胞和體液免疫應答等等。When the body suffered from malignancy, on the one hand, tumor restrained cell immunity function, antibody ' s production and the body ' s immunity effect through inducing restraining t cell, so it accelerated tumor ' s growth, on the other hand, tumor induced body fluid restrained gene, which prevented t cell and nk cell from killing tumor and restrained lymphocyte to mitotic multiplication reaction, indeed it accelerated tumor ' s growth
當機體一旦患上惡性腫瘤后,一方面腫瘤通過誘導抑制性t細胞,抑制細胞免疫功能及抗體的產生,抑制機體對腫瘤的免疫效應,從而使腫瘤逃逸機體的免疫監視,促進腫瘤的生長。另一方面,腫瘤通過誘導體液抑制因子阻止t細胞和nk細胞的等對腫瘤的殺傷作用,抑制淋巴細胞對有絲分裂原的增殖反應,甚至促進腫瘤的生長。分享友人