泛素 的英文怎麼說

中文拼音 [fànsù]
泛素 英文
ubiquitin
  • 泛 : Ⅰ動詞1 [書面語] （漂浮） float; drift 2 （透出; 冒出） be suffused with 3 （淹沒） inundate; floo...
  • 素 : Ⅰ形容詞1 （本色; 白色） white 2 （顏色單純） plain; simple; quiet 3 （本來的; 原有的） native Ⅱ名...
  1. Whole mount in situ hybridization showed that amphihmgb transcripts were present ubiquitously in the early embryos from zygote to neurula, but they decreased gradually in mesoderm and endoderm and neural tube with development, and became restricted to epidermal cells in the hatched larva. it appear s that hmgb plays a role in the mitosis and differentiation of embryonic cells. another amphioxus cdna, amphiubf80, encoding ubiquitin / ribosomal fused protein s27a, was isolated from the gut cdna library of b. belcheri tsingtauense

    S004cdna序列編碼一個156個氨基酸殘基組成的蛋白質，與人的泛素蛋白ubf80具有較高的氨基酸序列同源性（ 145 / 156同源） ，且該蛋白具有泛素蛋白ubf80所共有的兩個結構域，即由72個氨基酸組成的泛素介導的蛋白降解結構域和由48個氨基酸組成的核糖體蛋白s27a結構域。
  2. In the dna postreplication repair ( prr ) rad6 epitasis pathway, the error - free group comprises rad 18, rad5 and the mms2 - ubc13 heterodimer factors

    泛素系統通過對細胞內短期存在蛋白的及時降解而在各項生命活動中起著重要作用。
  3. We have identified in s. cerevisiae distinct ubiquitin - ligase complexes that define different erad pathways

    我們在酵母體內發現了一種參與不同erad途徑的特定的泛素連接酶復合體。
  4. To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei, and to study the function and mechanism of mint - mediated transcription repression, yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5, amino acids 2226 - 2959 ). from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo, fifty - one were positive for nutritional screening and p - galactosidase assay. restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments, which are mint, alpha a - crystallin - binding protein i ( alphaa - crybpl ), and nuclear receptor co - repressor 1 ( n - corl ), respectively

    鑒于mwt基因編碼區較長，共有10799個堿基，故此我們將mint分為六段，分別命名為fi一f6 ，本研究以其中的f5 （ 222e959 ）和f6 （ 296s576 ）片段為研究對象，將h者分別插入pgb盯7載體中，結果顯示： mintfs可與核受體輔助抑制因子1階cori ） ， o晶狀體蛋白結合蛋白1hlphatcrybp入及mw加互作用，而f6可與igm的重鏈恆定區、泛素結合酶2l6和一個未知功能的新的蛋白基因進行結合。
  5. We have known that ir may activate ubiquitin - proteasom pathyway, our experiments focus on whether ubiquitin - proteasome pathway involves in the regulation of p27klpl during ir responses

    我們知道ir能激活泛素化蛋白酶體途徑，那麼，泛素化蛋白酶體途徑是否參與ir誘導p27物』蛋白表達的調控
  6. Northern blot analysis showed that the mrna level of p27 k ' pl had no changes during ir responses ; the level of ubiquitinated p27klpl increased following 10gy - irradiation ; mg - 132 ( proteasome inhibitor ) inhibited the degradation of

    我們通過初步的研究結果揭示: northem檢測結果表明ir對p27kip 『 mrna水平無明顯影響; ir誘導p27kip 』泛素化水平的增加;蛋白酶體抑制劑（ mg一1
  7. Both rad6 and ubcls are ubiquitin - conjugating enzymes, and mms2 is a ubc - like protein. radls and rad5 are both single strand binding ring linger proteins. rad6 binds to radls and mms2 - ubcls binds to rad5

    在泛素系統中起主要作用的是三種酶：泛素激活酶e1 ；泛素綴合酶e2 / ubc和泛素連接酶e3 。
  8. And also for the establishment of the technique, we were interested in examining whether rad18 plays a role in this ho - induced dsb repair in s. cerevisiae. to measure the association of radls with dsb, we used the chromatin immunoprecipitation ( chip )

    但是具體這一修復復合物的泛素化底物蛋白是什麼，它們又具體結合於什麼樣性質的dna損傷部分，目前並不清楚，而這兩點是研究泛素系統在dna修復中的作用的關鍵。
  9. " for the discovery of ubiquitin - mediated protein degradation

    發現了泛素調解的蛋白質降解
  10. In the 317 unigenes of 592 clones, 42 novel full - length genes and 90 novel testis - specific transcripts were obtained. they were deposited in the genbank. one of testis - specific transcripts, testis - specific calpastatin ( tcast ) and two novel full - length genes, nyd - sp27 and human ubiquitin - like fusion protein ( hufp ), were selected for study

    我們對其中的一個睪丸特異的轉錄本一鈣激活的中性蛋白酶古制物（ testi specificcalpastatintcast ） ，和兩個新的全長基因一nd七p27和人泛素樣融合蛋白山umanublqultln likeusionproteinhwp ）進行了進一步研究。
  11. Effects of ubiquitin proteasome inhibitor induced endoplasmic reticulum stress and apoptosis on dopaminergic neuron

    泛素蛋白酶體抑制劑誘發多巴胺能神經元內質網應激反應及其凋亡的作用
  12. However, the ubiquitylated substrate protein of these ubcs remains unknown, and the nature of the dna to which the repair factors bind is still unclear

    這三種酶協同作用把泛素分子鏈作為標簽連接在目的蛋白上使之被26s蛋白酶體識別而降解。
  13. A defective protein, which binds polyubiquitin chain ( so - called " degrading label " ) through its - amino group of lys residue, is degraded in the proteasome

    對于需要清除的蛋白質，通過其賴氨酸殘基側鏈-氨基連接多聚泛素鏈（降解標簽） ，繼而在蛋白酶體中被降解。
  14. By combining the information from the cdna sequences with functions of their homologs, we suggest that two kinds of hormones may play important roles during flower regeneration in a few ways : ( i ) proteolytic system of ubiqutin / 26s proteosome complex, ( ii ) actin - dependent vesicular cycling of auxin efflux carrier, ( iii ) regulating transcription of genes, ( iv ) phosphorylation and dephosphorylation

    經過進一步的篩選，結合序列特徵和同源基因的功能信息對這些基因功能進行了初步分析。認為兩種外源激素可能通過泛素26s蛋白酶體復合體對調節蛋白的降解機制，生長素運輸載體肌動蛋白依賴的小泡運輸，基因轉錄調節，磷酸化和去磷酸化等調節過程誘導風信子花分生組織的再生。
  15. So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer

    泛素介導的蛋白質降解途徑的異常與許多疾病特別是腫瘤的發生密切相關。
  16. By sequencing random - selected clones from the library and using bioinformatics, 54 novel expressed sequence tags ( ests ) were obtained, in which there were 14 full - length cdnas, including peroxiredoxin gene, hmg - box gene, ubiquitin gene, signal recognition particle, acetyltransferase gene and lysozyme gene

    有14個克隆包含有完整的開放閱讀框，其中包括抗氧化物酶基因prx 、 dna結合蛋白基因、泛素基因、信號識別蛋白基因、溶菌酶基因和乙酰基轉移酶基因等具有重要生物學功能的基因。
  17. The dna double strand break ( dsb ) can be rejoined by at least two discrete pathways, i. e., the homologous recombination and the nonhomologous end - joining. at least 10 genes were found involved in nhej

    Rad18是一種單鏈dna結合蛋白，具有許多泛素系統e3所有的典型ring結構，與rad6 （ ubc2 ）形成結合緊密的異二聚體。
  18. Advance in ubiquitin and ub - associated proteins encoded by viruses

    病毒編碼泛素及相關蛋白的研究進展
  19. Further, eif - 5a overexpression through transfection promoted up inhibitor - induced apoptosis, and. mutation of eif - 5 a abolished the enhancing effect, we could conclude that the accumulation of hypusine - absent eif - 5a played an important role in the strong induction of apoptosis by up inhibitors

    進一步的分析結果表明過表達eif - 5a ，可增大細胞對mg - 132的敏感性，而hypusine突變體無此現象，說明未形成hypusine的eif - 5a可促進阻斷泛素通路誘發的凋亡作用。
  20. So the main objective of my phd work is to investigate the role played by the ubiquitin system during dna repair

    在dna損傷修復中，幾種泛素系統中的酶起著至關重要的作用。
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