病毒基因組 的英文怎麼說
中文拼音 [bìngdújīyīnzǔ]
病毒基因組
英文
viral genome- 病 : Ⅰ名詞1 (疾病; 失去健康的狀態) illness; sickness; disease; malum; nosema; malady; morbus; vitium...
- 毒 : Ⅰ名詞1 (對生物體有害的性質或物質; 毒物) poison; toxin 2 (毒品) drug; narcotics 3 (姓氏) a s...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 組 : Ⅰ名詞1 (由不多的人員組成的單位) group 2 (姓氏) a surname Ⅱ動詞(組織) organize; form Ⅲ量詞(...
- 病毒 : [醫學] virus; inframicrobe (濾過性)
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It refers to the release of the viral genome from its protective capsid to enable the nucleic acid to be transported within the cell and transcribed to form new progeny virions
它指的是將病毒基因組從它的保護性衣殼中釋放出來,使核酸能在細胞內轉運並能轉錄以形成新的子代病毒。Thought of the invention patent protection on coronary virus gene croup of sars
冠狀病毒基因組發明專利保護的思考Most of the human sars - coronavirus sequences differ from the sequences of the coronavirus isolated from himalayan palm civets by the lack of 29 units of genetic code in one region of the virus
絕大多數在人類身上發現的sars冠狀病毒基因組列序,比果子貍上發現的列序,在某個特定的部位上少29個基因密碼。A conservative motif, recognized by proteinases of potato virus y, was inserted between nib and ppiv, which will release functional ppiv from the fused protein after infection by potato virus y. then, plant expression vector pnpa was constructed by ligating the fusing gene and pbi121, which is knocked out gus gene
以馬鈴薯y病毒的復制酶( nib )基因為模板,通過聚合酶鏈式反應獲得nib基因,並在nib基因末端保留了在病毒基因組中nib與外殼蛋白( cp )基因相銜接的保守序列。Professor anthony chan, director of the hong kong cancer institute and chairman of the department of clinical oncology at the chinese university of hong kong, and professor qian tao, head of the cancer epigenetics and tumour virology laboratory in the sir yk pao centre for cancer, have successfully demonstrated for the first time in a group of npc patients who have failed standard therapies, that demethylation of the ebv genome can be achieved using azacytidine, a study published in the journal of clinical oncology with a leading editorial describing the work as " a model for future trials in solid tumors "
香港中文大學腫瘤學繫系主任兼香港癌癥研究所總監陳德章教授及腫瘤學系副教授陶謙教授,最近首次成功地在一組常規治療已經無效的鼻咽癌患者身上,利用氮胞? ( azacytidine )達致eb病毒基因的去甲基化,有關研究報告發表在《臨床腫瘤學報》上,而該期的一篇社論更形容是項研究是將來腫瘤臨床試驗的典範。Successfully cloned and constructed infectious full - length cdna of attenuated lapinized csfv chinese - strain ( derived from spleen ) could make us get pure rna virus genome of csfv c - strain, and further study and utilize mutation, deletion, insertion and substitution of csfv gene on dna molecular level
中國豬瘟兔化弱毒(脾淋毒)全長感染性cdna的克隆和構建,可以使我們得到純粹的csfvc -株rna病毒基因組,在dna水平上研究和利用csfv的基因突變、缺失、插入和替換。Several baculoviruses such as acmnpv, ldmnpv and busunpv contain conotoxinlike genes, but the biological function of these genes is unknown
桿狀病毒類蝸牛毒素是一類小分子肽,在acmnpv 、 ldmnpv和busunpv等一些桿狀病毒基因組中存在,但其確切的生物學功能尚不清楚。The proviral genome cdna clone of snv strain was digested, and the fragments was cloned into the puc18 vector, sequenced, finally we got the sequence of snv genome. the two pairs of primers were designed and synthesized according to the snv strain env sequence. the env genes of the rev isolates isolated from china were amplified by polymerase chain reaction ( pcr )
根據網狀內皮增生癥病毒snv株env基因的序列,設計並且合成了兩對引物,利用該引物,以中國地方分離株sd9901 、 ha9901前病毒基因組cdna為模板,通過pcr技術,成功的從國內分離得兩株rev毒株中擴增出env基因,並將之克隆進pucm - t載體中測序。The ns5 protein of dengue virus is the largest molecule encoded by the virus genome with a molecule weight of 104 000. recent research work indicates that the ns5 protein acts as the rna - dependent rna polymerase ( rdrp ) in virus which has the ability to recognize and bind its template rna to synthesize a complementary strand
近年來的研究表明, ns5蛋白具有rna依賴的rna聚合酶( rdrp )功能,即可以識別具有相對特異性的模板rna並與之結合,合成與模板互補的rna鏈,在病毒基因組復制過程中起關鍵作用。The analysis revealed that the sars - coronavirus was mutating continuously throughout the epidemic. the estimated mutation rate of the virus, however, is one - third that of the virus responsible for the acquired immunodeficiency syndrome ( aids )
分析結果顯示sars冠狀病毒雖然演變迅速,但sars冠狀病毒基因組的中性突變率只是愛滋病毒基因組的突變率的三分之一。It has made the strong basis for further studying mechanism of replication, virulence and determinant, attenuation, pathogenesis, functions of genetic products, specific diagnosis, cell and host tropism, development of dna vaccine and marker vaccine of csfv, and provided an excellent tool for molecular virology. main research contents include : based on published nucleotide sequences of csfv and by the help of computer analysis software, high conservative regions and single restriction enzyme sites of genome were selected. utilizing rt - pcr and nested - pcr techniques, 7 overlapping cdna fragments covering the full genome of csfv c - strain were successfully amplified
中國豬瘟兔化毒(脾淋毒)基因組cdna文庫的構建、序列分析:根據已發表的豬瘟病毒( csfv )核苷酸序列,藉助計算機軟體分析,選擇高保守區段和基因組中的單一限制性酶切位點,利用rt - pcr及nested - pcr和helf - nestedpcr技術,成功地擴增出了覆蓋c -株全基因組的7個cdna重疊片段f1 f7 ,分別克隆到pmd - 18t或pgem - teasy載體進行測序后,拼接出了其核苷酸序列。The complete nucleotide sequences of two strain viruses were determined. ten pairs of primers were designed based on the nucleotide sequences of tbev sofjin - ho, oshima5 - 10 by dnastar software. the virus cdna was expanded by rt - pcr in ten parts. sequenced by clones method. 5 " terminal and 3 " terminal cdna was expanded by race method. the nucleotide sequences and deduced amino acid sequences of two strain viruses were compared with the sequences in genbank by dnastar software
根據genbank中已公布的tbevsofjin - ho株和oshima5 - 10株核苷酸序列利用dnastar軟體設計10對引物,利用rt - pcr技術分段擴增病毒cdna ,克隆法測序。病毒基因組5末端和3末端序列採用race法擴增。測序結果用dnastar軟體拼接,在genbank中檢索6株tbev編碼區核苷酸序列、 12株tbeve蛋白核苷酸序列,並在dnastar上進行核苷酸序列、由此推導的氨基酸序列比較及構建系統發生樹。In this research, the gpv hl isolate was propagated with 13 day ' s duck embryos. a pair of primers gflgr used to arnplify vp3 gene was designed using oligo4. i software according to the whole nucleotide sequence of gpv b isolate published by zadori. the major structural protein vp3 gene was amplified from the dna of gpv hl isoiate by polymerase chain reaction ( pcr ), and then cloned into pmdl8 - t vecter
根據zadori等發表的gpvb株全基因核苷酸序列,藉助oligo4 . 1軟體設計了1對用以擴增主要結構蛋白vp3基因的引物gf / gr ,通過pcr技術,從病毒基因組dna中擴增出病毒主要結構蛋白vp3完整基因片段,經酶切鑒定后直接與pmd18 - t質粒載體連接。The polymerase is crucial in this process because it copies the iral genome and directs the production of its proteins.
在這個過程中多聚酶是至關重要的,因為它復制病毒基因組並且指導其蛋白質的合成The centre of excellence, located at the hepatitis research laboratory in the prince of wales hospital, can offer viral genome sequencing for patients who receive anti - viral therapy
中心於威爾斯親王醫院的肝炎研究實驗室,可以為接受抗病毒治療的乙肝病人進行病毒基因組排序。There are many mutations leading to drug resistance exist in the viral genome which varies in different individuals especially in those receiving different anti - viral drugs
不同乙肝病人在接受不同程度的抗病毒藥物治療后,病毒會出現各式各樣的變異,導致病毒基因組產生抗藥性。The locus of ha34 is quite interesting because a species - unique gene is often appeared in the same region of several other baculoviral genomes, suggesting it is phylogenetically active site
Ha34在基因組中的位置是其它桿狀病毒基因組特有基因經常出現的地方,暗示該基因所處的位置是進化的熱點。In this review, the developments made in the structure and function of the genome, molecular diagnosis methods and the molecular basis of the ibdv variation and so on were briefly described
文章概述了在傳染性法氏囊病毒基因組結構和功能、分子生物學診斷方法和病毒變異的分子基礎等方面的研究進展。However, a surprising finding of the present study was the isolation of a sars - coronavirus sequence that had a further deletion of 386 units of the genetic code in the same region of the virus genome
令人感到意外的是,疫癥後期在人類身上發現的sars冠狀病毒基因組列序,該特定的部位上發現缺少了多達386個基因密碼。For diagnostic tests to be effective for the detection of the different strains of the sars - coronaviruses, the tests should be developed to target regions of the virus genome that are less likely to mutate
鑒于sars冠狀病毒有不同的種類,在研製測試的過程中,必須針對病毒基因組列序中比較穩定的部份,才能有效地測試sars病毒。分享友人