細胞復制周期 的英文怎麼說
中文拼音 [xìbāofùzhìzhōuqī]
細胞復制周期
英文
cell replication cycle- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 復 : Ⅰ形容詞1 (重復) repeated; double; duplicate 2 (繁復) complex; compound Ⅱ動詞1 (轉過去或轉過...
- 制 : Ⅰ動詞1 (製造) make; manufacture 2 (擬訂; 規定) draw up; establish 3 (用強力約束; 限定; 管束...
- 周 : Ⅰ名詞1 (圈子; 周圍) circumference; periphery; circuit 2 (星期) week 3 [電學] (周波的簡稱) c...
- 期 : 期名詞[書面語]1. (一周年) a full year; anniversary 2. (一整月) a full month
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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" dr. gorbsky ' s results provide elegant proof that the cell cycle must be precisely controlled, " said rodger mcever, vice president of research at the facility. " now he and his lab can work toward developing innovative methods to probe and better understand the complex process of cell division. the research is detailed in the april 13 issue of the journal nature
該基金會負責研究工作的副主席羅傑麥凱維爾說, 「戈爾博斯基博士的研究成果為下面這種觀點提供了非常有力的證據,那就是細胞分裂的循環周期必須處于精確控制之下」 , 「現在他及其所在的實驗室可以致力於開發出更具創新性的研究方法,以對細胞分裂進行進一步的探索,並使人們能夠更為深入詳細地了解細胞分裂的復雜過程」 。They are positive regulating proteins and play a very important role in the development of neoplasma. cki are negative regulators taking part in cell cycle, which can directly or indirectly combine with the corresponding cdks to inhibit their activity. cyclin - cdk - cki constitutes a complex network regulating cell cycle
細胞周期蛋白依賴性激酶抑制因子( cyclindependentkinaseinhibitors , cki )可直接抑制相應的cdk活性或通過與cyclin競爭性結合cdk而起到抑制cyclin - cdk復合物的活性,從而作為負性調節因子參與細胞周期調控。In the laboratory experiment part, human peripheral blood, cultured cells and icr mice were study objects. the changes of mitotic chromosome numbers were measured by human metaphase chromosome counts and statistic analyzed used x2 - test. the changes of meiotic chromosome numbers were measured by mice one - cell zygote chromosome counts and statistic analyzed usedx2 - test. the effects of low dose ionizing radiation on the expression of topoisomerase ii were measured by immunocytochemistry, western blot and rt - pcr
流行病學結果顯示長期小劑量輻射接觸與染色體不分離呈正相關,為進一步在細胞遺傳學和分子生物學方面研究小劑量電離輻射與染色體不分離關系及其機制,本課題第二部分以外周血、培養細胞、 icr小鼠為研究對象,用外周血染色體計數和單細胞受精卵染色體計數的方法研究小劑量輻射和拓撲異構酶復旦大學2000級博士生學位論文11a抑制劑及其二者的協同效應對有絲分裂和減數分裂染色體不分離的影響,用免疫細胞化學染色、 westernblot 、 rt pcr等方法研究了電離輻射引起拓撲異構酶a表達變化。Doc - 1r gene is an candidate tumor suppressor gene which was discovered by zhangxue. it can interact with cdk2 specifically and restrain cdk2 transportation into the nucleus, which will block the formation of cdk2 and cyclin complex and hinder the process of cell cycle
Doc - 1r基因是張學等發現的一個候選抑癌基因,它可與cdk2特異性結合,抑制cdk2的入核轉運,使cdk2不能與cyclin形成復合物,從而阻抑細胞周期的進程。The fluorescence intensity in high - passage cells was increased obviously ; whereas the mitochondrial membrane potential was decreased obviously
結論內皮細胞在復制性衰老過程中,伴隨著細胞形態退化、細胞周期異常,細胞內自發熒光產物增加,線粒體膜電位降低。Rapid responses occured when cells were exposed to genotoxic stresses : one is initiating dna damage checkpoint that leads to arrest in gl, in order to provide the cell with sufficient time to repair damaged dna, or leads to arrest in g2, in order to avoid defective chromosome happening mitosis. on the other hand, if damage to the genome is excessive, the cells initiating apoptosis, when damages cannot be repaired
這是因為細胞在受到諸如電離輻射等基因毒應激損傷時,細胞最先作出的細胞學反應:一,起始dnadamagecheckpoint使細胞周期阻滯( arrest )在g1期,贏得時間識別與修復損傷,避免損傷的dna進行錯誤的復制,或和阻滯在g2期,避免缺陷的染色體進一步分裂;二,損傷嚴重而修復無望啟動細胞死亡程序,清除那些帶有病變傾向的細胞危害機體。Cdk2 is an important member in cdks family, it directly participates regulation of g ^ s checkpoint and dna replication in s phase, its activity and functional regulation is one of the crucial key in cell cycle ' s operation, otherwise ; cdk2 has very close relation with cell canceration
Cdk2是cdk家族中的重要成員,它直接參與細胞周期g _ 1 / s限制點( checkpoint )和s期dna復制的調節,它的活性和功能調節是細胞周期運轉的關鍵環節之一,與細胞癌變有著十分密切的關系。Pkc - mediated control of these transitions can be negative or positive, depending on the timing of pkc activation during the cell cycle and on the specific pkc isozymes involved
Cki是近年來分離得到的一類很重要的細胞周期調控蛋白,這些蛋白在體外通過與cdk 、 cyclin或cyclin - cdk復合物的結合,抑制cdk的活性,進而抑制細胞周期的進程。分享友人