細胞粘附肽 的英文怎麼說
中文拼音 [xìbāoniánbùtài]
細胞粘附肽
英文
arg-gly-asp- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 粘 : 粘動詞(粘附) glue; stick; paste; adhere to; bond
- 附 : Ⅰ動詞1 (附帶) attach; add; enclose 2 (靠近) get close to; be near 3 (依從; 依附) agree to; ...
- 肽 : 名詞[化學] (有機化合物) peptide
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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Effects of motif rgd - containing small peptides on cell adhesion
的短肽對細胞粘附作用的影響Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis
在上皮細胞內,連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白( e - cadherin )的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白( -連環蛋白) - -連環蛋白組成的粘附連接體( adherensjunctions , ajs ) ,這種復合體對維持細胞正常的粘附功能是必需的。Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities
因此將這些蛋白包被、固定到材料表面,觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節,並從以下方面進行探討: ( 1 )採用不同原代細胞分離方法,研究其對mscs細胞的生物學特性影響。 ( 2 )檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 ( 3 )分別採用型膠原及纖維粘連蛋白( fibronectin , fn )包被聚乙醇酸-乳酸共聚物( poly ( 1actide - co - glycolide ) , plga )膜及多孔塊型plga材料,觀察細胞在單層或三維培養狀態下,型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。Objective : laminin 5 is a hetertrimeric glycoprotein with a strong adhesive function consisting of three polypeptide chains ( 03, f ^ y 2 ) that is secreted by keratinocytes
目的: ln - 5是一個由三條多肽鏈( 3 、 3 、 2 )組成的異三聚體的糖蛋白,由角質形成細胞產生的,具有強大粘附功能。The study of in - situ construction of cytocompatible surface on pdl - la matrix via amphiphile - amino acid ( rgd ) hybrid self - segregation - the amphiphilic diblock copolymer, poly ( dl - lactide ) - poly ( ethylene oxide ) ( pla - peo ) copolymer, containing hydrophobic pla block and hydrophilic peo block was synthesized via coupling method in this dissertation. cell - adhesion - promoting amino acids and integrin receptor peptide rgd were then immobilized at the end of peo chain of pla - peo copolymer via hydroxyl group activation technique. the solvent blending and casting method was then used to obtain the amphiphile modified pdl - la membranes
兩親共聚物-氨基酸( rgd )雜化體原位自修飾構建聚乳酸細胞相容性表面的研究一本論文首先設計併合成了一類含疏水聚乳酸( pla )鏈段和親水聚氧乙烯( peo )鏈段的兩親嵌段共聚物材料( pla - peo ) ,利用peo鏈端的活性官能團羥基固定了促細胞粘附的氨基酸及整合素配體多肽片段rgd 。分享友人