結合型藥物 的英文怎麼說
中文拼音 [jiēgěxíngyàowù]
結合型藥物
英文
bound drug- 結 : 結動詞(長出果實或種子) bear (fruit); form (seed)
- 合 : 合量詞(容量單位) ge, a unit of dry measure for grain (=1 decilitre)
- 藥 : Ⅰ名詞1 (藥物) medicine; drug; remedy 2 (某些有化學作用的物質) certain chemicals Ⅱ動詞1 [書面...
- 物 : 名詞1 (東西) thing; matter; object 2 (指自己以外的人或與己相對的環境) other people; the outsi...
- 結合 : 1 (發生密切聯系; 聯合) combine; unite; integrate; link; binding; coalition; cohesion; connectio...
- 藥物 : medicinal; medicine; medicant; medication; drug; pharmaceuticals; medicaments
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Abstract : several - aromaticamino ketones, which were designed according to some hypothetical models of the cyclooxygenase and 5 - lipoxygenase active sites, were synthesized by an amino exchange reaction. the structures of the eight new compounds were confirmed by ir, 1h - nmr and elemental analysis. the results of the pharmacological tests showed some of the investigated compounds had significant anti - inflammatory activity on croton oil - induced ear edema of mice
文摘:根據環氧化酶、 5 -脂氧化酶活性中心結構模型設計了一組-芳胺酮類化合物,並用胺交換反應合成了這些化合物.經紅外光譜、核磁共振氫譜及元素分析證實了8個未見文獻報道的化合物的結構.藥理實驗結果顯示.部分受試化合物在巴豆油誘發小鼠足趾腫脹模型中表現出一定的抗炎活性This millirod system incorporates multiple components : a plga matrix ; excipient in free and complex forms ; drug in free, bound, and crystalline forms
這個微囊系統包括多種成分: plga基質;單一和復合型賦形劑;游離、結合和結晶型藥物。On the basis of modern blasting theories, the moving process of explosive stress field of multi - row and simultaneity is analyzed and the characteristics of stress field inspired by equivalent effect cell of globosity charge in cylindrical charge structure are considered. thus energy distributing equation of detonator explosion is established and the explosive energy utilizing rate factors are known. so the moving process model of the hole filling is constructed and the equation of calculating reasonable filling length is produced
本文在現代爆破理論的基礎上,分析了多排同段爆炸應力場的作用過程以及柱狀裝藥結構中等效單元球狀藥包所激發的應力場特點,建立了炸藥爆炸能量分佈方程,明確了影響爆炸能量利用率的因素,構建了炮孔充填物運動過程模型,得出計算合理充填長度方程。Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has shown promising preclinical and clinical activity against metastatic colorectal cancer, particularly in combination with chemotherapy
背景:一種新型的抗血管內皮單克隆抗體貝伐單抗在基礎以及臨床研究中均對轉移性結腸癌表現出良好的治療效果,尤其在與其他化療藥物結合時效果更佳。Conclusions : for pediatric breathing patterns, mask design is a key factor defining budesonide delivery to the lungs, face and eyes. front - loaded nebulizer - mask combinations are more efficient than bottom - loaded systems
結論:對于兒科呼吸模式,面罩的設計是決定藥物傳輸至肺部,眼部和面部的關鍵因素。前端插入霧化器型面罩組合比底部插入組合更為有效。To get in vivo evidences that apoplast calmodulin con 1d regulate plant growth and development process, a chimeric secretion form of calmodulin binding peptide, which contains a signal peptide, a calmodulin binding domain and a c - myc epitope was constructed. the chimeric gene was introduced into arabidopsis. it was expected that the overexpression of this chimeric protein could be secreted into cell wall and bound to apoplast calmodulin, which could reduce the apoplast calmoduin concentration to make an apoplast camodulin " antisense " plant. by observing the potential phenotype change of apoplast calmodulin " antisense " plant, the in vivo function of apoplast calmodulin on plant growth and developmental process could be speculated
但這些多是採用生理學手段和藥理學方法而得出的體外( invitro )實驗結果,為了取得質外體cam在植物生長發育過程中發揮重要作用的invivo實驗證據,根據動物中的一些研究方法,本實驗設計並構建了帶有信號肽、 cam結合肽( can小肽) 、 epitope ( c - myc )融合基因的載體,並將融合基因通過真空滲入法轉入擬南芥,預期過表達的融合蛋白將會被分泌到細胞外並與質外體cam相結合,這樣就會抑制質外體cam的功能,從而可以構建質外體cam的「反義」植株,通過觀察質外體cam 「反義植株」的表型改變,就可以推斷質外體cam在植物生長發育過程中的功能。Based on the revealed relationship between the secretary structures and substances, the secretary tissues of hypericum are classified into 2 main types : type i is the tissue that secretes and stores such dianthrone compounds as hypericin. this a group of secretary cells, forming into black glands. type ii is the tissue that secretes and stores essential oils
進行了金絲桃屬藥用植物分泌組織的系統研究,揭示出其分泌結構與分泌物質的關系,並在此基礎上提出了該屬藥用植物分泌組織主要類型的劃分:一類是分泌和貯存二蒽酮金絲桃素類化合物的組織,多為分泌細胞組成的細胞團,形成黑色腺體;另一類是分泌和貯存揮發油類成分的組織,是裂生性的分泌腔或分泌道,常形成半透明腺體。The yield and the main botany properties of four culture types of medicinal chrysanthemum morifolium were compared and analyzed by adopting the randomized block design in the field experiment
摘要採用隨機區組田間試驗設計,結合方差統計分析方法,對藥用白菊花4個栽培類型的產量和主要植物學性狀進行比較分析。During the past fifty years, it was widely used to measure the chemical properties of molecules in the fields of structural chemistry, organic chemistry, and pharmacy etc. in 1997, a particular international conference was held to celebrate the fiftieth anniversary for the invention of the index, and published a special issue for the proceedings of the conference in discrete mathematics to memorize it
五十多年來統計化學、結構化學、有機化學、藥物研究等方面廣泛採用這一指標來測量分子的性能。 1997年國際上還專門召開了學術會議以慶祝這一指標提出五十周年,並出版論文專集以示紀念;這也主要是因為近年來,組合化學在國際學術界的興起,為尋找新的物質(特別是有機物、新型藥物)奠定了理論基礎。The reasonable model of exploiting and utilizing to the plant resources is put forward, which should be mainly protected. all kinds of communities are analyzed. the aubor ' s average height of karst evergreen - deciduous forest is 6. 88m. theuper arbor ' s average height is 13. 07m. the highest one reaches 25m. the community cover ratio is over 90 %, only few gaps existnatural convalescence forest is inferior to karst evergreen - deciduous forest in the restoration degree. there are a few tall arbor in the community. the height of alpine shrubs forest is 1. 00 to 2. 00m. there is no dominant species. the average height of karst shrubs forest is 0. 97m. the rhus chinensi s, desmodium racemosum and golochidion pubrum are the dominant species
以觀賞及綠化樹種、用材樹種和藥用植物等歸類對洛塔植物資源作出了評價,觀賞植物主要有:玉趼、百合、繡球花等;用材樹種有大葉櫸、香果樹、光灰楸等;藥用植物有南方紅豆杉、杜仲等,並提出了對植物資源以保護為主的合理開發利用模式。分析各類型植物群落的保護年齡,地質與土壤背景以及群落基本結構和特徵,喀斯特常綠落葉林喬木層平均高度為6 . 88m ,上層喬木平均高13 . 07m ,最高可達25m ,群落郁蔽度達90以上。Moreover, because the model can be easily transported through internet, many scientists can share it. the work also prepares to search the idea 3d structures and screens chemical depend on object molecular. it is very important, for the work of drug design
由於其自身具有傳輸容易的特點,製作的藥物分子模型可以實現網路傳輸,用於在在internet上實現分子3d結構顯示,實現了對網路庫中活性分子的三維結構的共享,被眾多的研究者使用,為實現三維結構搜索,根據靶位的空間結構來篩選活性化合物,對藥物先導化合物的發現和分子設計打下堅實的基礎。The result of numerical taxonomy indicated that there were high phenotypic diversity among the strains isolated from the root nodules of pueraria spp. it can been seen in utilization of carbon and nitrogen sources, antibiotic resistance, resistance to dyes and chemicals, tolerance to acid, acid production, alkali production, nitrate reduction et al. the dendrogram divided all the strains into
數值分類對所有供試菌株進行了131項表型性狀的測定,結果表明,葛藤根瘤菌具有豐富的表型多樣性,表現在利用多種化合物作為唯一碳源、氮源能力,對抗生素、染料和化學藥物的抗性,耐酸性,產酸產堿情況,硝酸還原能力等方面。The distributions of various glands and their sizes and densities on leaves have also been observed. combining with the data obtained from ultraviolet spectra, it has been concluded that hypericin does not exist in sect ascyreia and sect spachinm. hypericin is only limited to sect hypericum and sect adenosepalum
還觀察統計了各類腺體的分佈及在葉片上的大小、密度,結合紫外光譜,總結提出的金絲桃組和地耳草組植物不含金絲桃素、金絲桃素僅局限分佈於貫葉連翹組和遍地金組的結論,具有典型的植物化學分類意義及藥材品質評價意義。This modeling study shows that complex binding capacity, which affects drug initial conditions, drug ? polymer interactions, and bound drug behavior in aqueous solution, is crucial in controlling drug release kinetics
此模型研究顯示復合包合容量影響藥物原始狀態、藥物-聚合物間相互作用及水溶液中結合型藥物的行為,其在藥物控釋動力學中起決定性作用。Acoording to company valuation theory, based on ananlysis and comparison of present company valuation model and valuation technology, combining characteristics of biopharmacy company of high technology, high risk, high profits, i take sichuan dikang science and technology pharmacy, a biomedical listing company for dcfm model value ' s valuation. through analysing dikang ' s past achievements and value - driving business, i made
本文根據公司價值的有關理論,對目前運用的公司價值評估模型和評估技術的進行分析和比較基礎上,結合生物制藥上市公司高技術、高風險、高收益等高新技術企業特點,選擇貼現現金流模型對物制藥上市公司? ?四川迪康科技藥業股份有限公司的價值進行評估。Located in remote mountain district as well as falling behind relatively in economy, according to its own unique geographical resource environment and actual developing level of social economy, yanbian is supposed to put " agriculture and forestry " in the fundamental position, complying with the characteristics of agriculture - and - forestry - oriented industry and giving full play to its unique ecological environmental conditions and special living resources, accelerates the paces of the ecological prefecture construction and focuses on the construction of local product industry, attaching importance to the production of such major products as chinese herbs and edible mushrooms, promotes the development of green industry at full speed, and proceeds to shift gradually to the production of organic products, last but not the least, fosters and develops new hi - tech industry that accords with its own industry characters to set up efficiency - related industry of ecological environmental protection and then have the preservation of ecological environment on the benign developing track in step with economic construction
地處邊遠山區經濟相對落後的延邊應根據自己獨特的地理資源環境和社會經濟實際發展水平,擺正「農林」產業的基礎地位,遵從工業的「農林」結構型特點。應充分發揮我州生態環境的獨特條件和特有的生物資源,加快生態州建設的步伐,注重狠抓特產業的建設,以中藥材、食用菌生產為重點,促進綠色產業的飛速發展,並使之逐步轉向有機產品生產。大力培育和發展與自己的產業特點相吻合的高新技術產業,建立生態環保效益型經濟,從而使生態環保與經濟建設同步走上良性的發展軌道。The cdna expression library that contains no intron theoretically include all expressed genes and conserve resource genes permanently. lt can be used to find out and clone some genes which can express particular protein with modern molecular biological techniques, such as immunological screening, drug - prob screening, southern et al. lt is very important to study the life nature of plasmodium falciparum in molecular level. with the developments of these studies, the drug - resistant mechanism of the plasmodium falciparum and the genes of some specific medicine binding protein can be made well - known. at the same time, the researches will do good to explain the mechanism of some specific medicines in order to design and screen new anti - malaria drugs
建立cdna表達文庫在一次永久保存基因資源的同時,可以利用功能篩選、免疫學篩選、藥物探針篩選、 southern雜交和大規模序列測定等現代分子生物學技術尋找特異性活性蛋白基因,進而克隆和表達這些基因,對從核酸及蛋白質等分子水平研究瘧原蟲的生命活動規律,對揭示其抗藥性分子機理,搞清某些特效藥物結合蛋白的基因及此類藥物的作用機制,對新型抗瘧藥物的合理設計及篩選都具有極其重要的現實意義。Is approved by the chinese national department of health, special work for the medicine of animal research and develop, produce, sell in scale and the specialization of one body to melt, modern extrovert type high - tech group company ; it applies modern biological project technology and high - tech detection equipment, strict test regucatory system, combine western advanced science and technology, management method and eastern peculiar humanity and market characteristic perfectly, found a advanced enterprise that has modern management characteristic ; it sets : china ? henan e ? d ? f animal medicine trade limited company, china ? shanghai e ? d ? f of the animal article limited company of health protection, china ? beijing e ? d ? f biological medicine trade limited company, china ? hong kong e ? d ? f biological chemical limited company
是經中國國家衛生部門批準,專業致力於動物藥品的研發,生產,銷售於一體的專業化、規模化、現代化的外向型高科技集團公司;它應用現代化生物工程技術,高科技檢測設備,嚴格的檢驗規章制度,將西方先進科技,管理方法與東方特有人文及市場特點完美結合,締造出一個具有現代化管理特色的先進企業;旗下設有:中國?河南易達菲動物藥業有限公司,中國?上海易達菲動物保健品有限公司,中國?北京易達菲生物藥業有限公司,中國?香港易達菲生物化工有限公司。In these dissertation, a theory mathematics model of the dynamic delay - time about hybrid igniting - device was established, including dynamic " solid - particle " effect model and " particle streamline " effect model of solid power in its igniting delay - time cannulation. at last, drew a conclusion of the theory mathematics model about dynamic delay - time on the sealed condition
包括動態下其點火延期管內固體火藥的「固體粒子」效應模型, 「粒子流線」物理模型,最後結合點火延期管內固體火藥所處密封性的特殊環境,得出其點火機構動態延期時間的理論數學模型。From the reported experiments, we found some interesting facts : in the experiments with no lil effects, some anesthetics ( ketamine, ether etc ) were often added during treatment schedule, whereas they were seldom used in the experiments with lil effects
我們在總結大量低強度激光照射治療動物皮膚傷口模型的實驗中發現:動物活體實驗中用於麻醉的藥物對實驗結果有影響。當麻醉藥物為氯胺酮等時,低強度激光照射往往不能促進動物皮膚傷日的愈合。分享友人