羥氯喹 的英文怎麼說
中文拼音 [qiǎng]
羥氯喹
英文
hydroxychloroquine；oxychloroquine-
Hydroxychloroquine is a recognized therapy for patients with pss
羥氯喹被公認用於乾燥綜合征患者。Hydroxychloroquine is known to hae marked pharmacokinetic ariability [ 45 ]
已知羥氯喹有明顯的藥動學可變性45 。In addition, we hae speculated on a new mechanism for the action of hydroxychloroquine leading to an improement in saliary flow rate
另外，我們推測了羥氯喹的一種新作用機制，升高唾液流速。Further work is needed to explore this possibility and we intend to determine the in io effect of hydroxychloroquine on saliary cholinesterase following 6 months of therapy
進一步的探索工作是必須的，我們試圖測定6個月治療后羥氯喹對唾液膽堿酯酶體內方面的作用。It is tempting to speculate that the high degree of ariability in the steady - state pharmacokinetics of hydroxychloroquine may explain why inconsistency in clinical improement is found in patients with pss taking hydroxychloroquine, as it is possible that only those patients who hae both a high glandular cholinesterase actiity and achiee high blood concentrations of hydroxychloroquine show improement in saliary flow [ 12, 14 ]
這是個具有吸引力的推測，穩態藥動學中羥氯喹的高可變性能解釋為什麼使用羥氯喹的患者臨床的改善不一致，同樣有可能，僅僅那些既具有高水平的唾液膽堿酯酶活性有具有高的羥氯喹血藥濃度的患者才顯示唾液流量的升高12 ， 14 。Taken together, these findings indicate that further work is needed to re - ealuate the use of hydroxychloroquine in the treatment of pss and that increased leels of saliary cholinesterase actiity could proe to be a useful marker to indicate those patients who would show an improement in their saliary flow rates if placed on hydroxychloroquine
這些所有的發現表明了進一步的研究是必須的，重新評價羥氯喹在治療原發性乾燥綜合征中的作用，以及唾液膽堿酯酶水平增加能證明作為一個有用的指標，以確認患者使用羥氯喹后唾液流速得到改善。分享友人