羥脫羥酶 的英文怎麼說
中文拼音 [qiǎngtuōqiǎng]
羥脫羥酶
英文
hydroxydehydrgenase-
Effect on prostaglandin dehydrogenase in hypothalamus in both the pyretic and hypothermia rats by guizhi tang
羥基前列腺素脫氫酶活性的影響Gc binds to mr with higher affinity than gr. this gc - receptor interaction is also controlled at the pre - receptor level by two important factors : corticosteroid binding globulin ( cbg ) and 11 b - hydroxysteroid dehydrogenases ( 11 - hsds )
糖皮質激素與受體結合的量除與血漿中糖皮質激素水平、皮質醇結合蛋白( cbg )濃度有關外,還受到細胞內受體前糖皮質激素代謝酶? 11 -羥基類固醇脫氫酶( 11 - hsd )的調節。The research team identified a second polymorphism, in a gene encoding an enzyme, 3 - beta - hydroxysteroid dehydrogenase, which also is associated with an increase in hot flashes
研究小組還鑒定了第二種多態現象, 3 -羥甾類脫氫酶的基因編碼,同樣和熱潮的增加關聯。Which may provide the molecular basis for the inberine regulation of ll p - hsdl expression by glucocorticoids. secondiy, the regulation of l l 9 - hsdl expression and redutase activity by glucocorticoids was investigated in the primny cultured human chorionic trophoblast
整個妊娠過程中胎盤11 - hsd活性以氧化酶為主,使母體gc在進入胎兒循環前大部分被轉化為無活性的17 -羥- 11 -脫氫皮質酮,保證胎兒正常發育所需的激素濃度。The rat 20a - hydroxysteroid dehydrogenase ( 20ahsd ) belongs to a family member of aldo - ketoreductases used nadph as a cofactor and principally converts progesterone to 20a - hydroxyprogesterone as a lower or non - active hormone. thus 20ohsd acts as a molecular switch and makes the potent progesterone hormone into an inactive potent metabolite
大鼠20 -羥類固醇脫氫酶( 20 - hydroxysteroiddehydrogenase , 20 hsd )屬于醛酮氧化還原酶系成員,在大鼠卵巢中以nadph為輔酶將孕酮轉變為低或無活性的20 -羥孕酮。L l6 - hsd2 is localized to the sppytiotrophoblast of the placenty providing a fimctional barrier protecting the fetus from matemal glucocorticoids. a sequence resembling glucocorticoid response element ( gre ) has been identified in the promoter region of the human l l0 - hsdl gene. glucocorticoids have been shown to induce the expression of 11p - hsdl in the hippomus in vitro " whereas controversial results were obtained in the hepatocyte
體內至少存在兩型11 - hsd ,在細胞完整的狀態下, 11 - hsd1主要為還原酶,它活化gc的代謝產物17 -羥- 11 -脫氫皮質酮(嚙齒類為脫氫皮質酮)為有活性的皮質醇(嚙齒類為皮質酮) ,而11 - hsd2為氧化酶,它催化皮質醇為無活性的17 -羥- 11 -脫氫皮質酮,因此11 - hsd1加強gc的作用,而11 - hsd2減弱gc的作用。分享友人