胞核轉移 的英文怎麼說
中文拼音 [bāohézhuǎnyí]
胞核轉移
英文
nuclear migration-
Among the genes, there were genes directly related to liver regeneration : fetuin, cathepsin ; close related to liver function : cytoplamic aspartate aminotranferase, gutathion sulfur transferase ; related to substance and energy metabolism : atp synthetase, ribosomal protein, and related to stress response : haptoglobin, transferrin
這些基因中有和肝再生有直接關系的如:胎球蛋白、組織蛋白酶;和肝臟功能密切相關的如:胞質天冬氨酸轉氨酶、谷胱甘肽硫轉移酶;與物質能量代謝有關的如: atp合成酶、核糖體蛋白;以及與急相反應有關的如:觸珠蛋白、轉鐵蛋白。Somatic cell nuclear transfer - the transfer of a cell nucleus from a somatic cell into an egg from which the nucleus has been removed
體細胞核轉移將體細胞中的細胞核轉移到另一個已去除細胞核的卵細胞中。Changes in p - catenin expression or localization were found in cancer cells and tumor tissues, it had been reported that p - catenin translocated from membrane at the normal condition into the cytosol or nucleus in cancer cells. recently, p - catenin has been referred to an oncogene
研究發現,癌變的細胞中-連環蛋白的分佈發生了異常,由胞膜轉移到胞漿和胞核,因此,已把-連環蛋白歸為一個新的癌基因。Results in the 260 slices of liver biopsy, there were 20 ones of acute viral hepatitis, 78 ones of chronic hepatitis, 79 ones of hepatocirrhosis, 28 ones of primary liver cell cancer, 27 ones of liver karyon heterogeneity, 20 ones of liver metastatic adenocarcinoma, 12 ones of fatty liver, five ones of alcohol liver, three ones of liver cyst, two ones of congenital bile duct atresia, six ones of illegible structure, 20 ones without liver cell or with few scattered liver cell
結果260例肝穿活檢組織病例中,急性(病毒性)肝炎20例;慢性肝炎78例;肝硬化39例;原發性肝細胞癌28例;肝細胞核異質27例;肝轉移性腺癌20例;脂肪肝12例;乙醇肝5例;肝囊腫3例;先天性膽管閉鎖2例;穿刺組織結構模糊6例;未穿到或僅穿到少量肝細胞20例。1. with testicular development, the products of c - myc translocate from the cytoplasm of spermatogonia to nuclei of spermatogonia
隨著精子發育時期的不同, cngc產物在山溪蛻精巢中有從生殖細胞的胞質向胞核中轉移的趨勢。P and pr have relationships with spermatogensis and sperm maturation. 6. the product of c - fos translocates from the cytoplasm of spermatogonia to nuclei of spermatogonia, then it induces the transcription of dna and regulate spermatogonial proliferation and spermatogenesis
C fos產物從精原細胞胞質中轉移到胞核中后通過啟動dna的轉錄而調控精原細胞的增殖,從而促進精子發生的進程。Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后,就與ajs發生解離而游離到細胞漿中,此時細胞的粘附功能也發生障礙,游離到胞漿中的-連環蛋白,一部分被抑癌因子apc降解,一部分則轉移到細胞核內,與核內的轉錄因子tcf lef結合,啟動與細胞增殖有關的基因轉錄。The protein product of meq gene was highly expressed in the nuclei of recombinant baculovirus infected sf9 cells when using an anti - meq monoclonal antibody ( mcab ) 23b46 to run the immunofluorescence assay ( fa ) ; the expression quantity and if staining patterns differed with different times post - infection ( pi ). the results of western blotting and immunoprecipitation test showed there were two specific bands around 60 kd. the results of the study demonstrated that the baculovirus / insect cell system is effective to be used to express nuclear protein of virus
結果發現:本表達系統產生的meq蛋白可被重組痘病毒表達的meq制備的單抗23b46所識別;在感染細胞中, meq蛋白僅局限於細胞核內,而且隨著感染后( pi )時間的增加,具有從核質向核仁和核膜轉移的趨向; w已stemblot和免疫沉澱試驗均證實重組桿狀病毒感染細胞裂解物中出現有兩條大小約為60kd的特異帶。The results of emsa showed the obvious retardant bands, which suggest that some proteins in nuclei can bind to the specific dna sequence of mbd3 gene after lps treatment. 5. the molecular mass of this dna binding protein was assessed between 43. 0 - 66. 2 kd by south - western blot
4 .電泳遷移率改變實驗有明顯的滯后帶形成,表明lps刺激后,肝臟組織的細胞核內有轉錄因子與mbd3基因特異的dna序列結合,參與mbd3基因的誘導表達5 . south一westemblot進一步確定此轉錄因子分子量在43 . 0一「 . 2kd之間。There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose
表皮生長因子( egf )能使p120 ~ ( ctn )酪氨酸磷酸化,磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強; p120 ~ ( ctn )在細胞內的分佈出現明顯的核內轉位, -連環蛋白也出現相似的變化。Clones are lost from the earliest developmental stages and throughout pregnancy. now more and more studies support the evidence on the failure of cloning : chromatin inappropriate epigenetic reprogramming, and then result in abnormal genes expression
大量的研究表明,克隆動物在核移植后其染色質的再程序化表現異常,使細胞不能成功地通過調節轉錄活性而有效地控制其發育分化。The mechanism is that the introduced complementary oligonucleotides can bind to the corresponding mrna or double - stranded dna in genome and form partial double - stranded molecules or triple - stranded nucleic acid molecules by sequence - specific and nonsequence - specific antisense action, thus the target gene will be orientationally blocked and expression of the target inhibited so that therapeutic effect could be attained. in this study, we designed a fragment of human c ii ta cdna in antisense orientation using mrna of c ii ta as template. the primers were designed based on 94 - 500 nucleotides segment in 5 " end of ciita gene so that the interested gene contained 407 base pairs which included two aug codons in 1 16 and 188 nucleotides as well as the splicing site between the first and the second exons
本研究設計以c tamrna為模板的反義cdna片段,從c ta基因5 』端第94位到500位核苷酸段設計引物,目的片段407bp ,覆蓋第116和188位兩個aug密碼子,也包含了第一外顯子和第二外顯子間的剪接位點:用常規分子生物學方法構建了反義片段的腺病毒表達載體( padeasy - 1系統) ;腺病毒載體經hek293細胞包裝產生含反義片段的重組腺病毒,用氯化銫密度梯度離心法獲得純化的高滴度腺病毒;進行體外基因轉移,分別用反義片段真核表達載體轉染p388d1細胞和用重組腺病毒感染hela細胞,觀察導入的c ta基因反義rna抑制細胞內組成型或誘導型c ta基因表達的作用,從而達到調控mhc -類分子表達的目的。By nuclear transferee transfered the nih 3t3 cell to enucleated gv and mii oocyte. the immunofluorescence results showed that jak. 2 was not transfered to somatoblast nuclear whether the recombined oocyte occured gvbd or not. when transfered somatoblast nuclear to enucleated and integrated m ii oocyte, the immunofluorescence results showed that jak2 only existed in the nuclear of integrated m ii oocyte but not the somatoblast nuclear. the nuclear transfer implied that the mature and immature oocyte cytoplasm could not transfer the jak. 2 protein to donor nuclear
通過核移植,將nih3t3體細胞核移入去核gv期和m期的卵母細胞中。熒光檢測發現,體細胞核與去核gv期卵母細胞質構成的重組卵無論是否發生gvbd ,核內均沒有jak2的出現。在去核和未去核的m期卵母細胞中移入體細胞核, jak2僅存在於未去核m期卵母細胞的核內,並不轉移到體細胞核內。Scientists have been warring over the issue of cloning a human child by body cell nuclear transfer
科學家們就通過人體細胞核轉移去克隆人的問題爭論不休。The bill, which will now go before the house of representatives, allows a process called somatic cell nuclear transfer ( scnt )
這項法案目前將優先於眾議院的決議,允許一項名為幹細胞核子移轉的實驗程序。分享友人