胞漿合胞體 的英文怎麼說
中文拼音 [bāojiānggěbāotǐ]
胞漿合胞體
英文
cystorrhexis syncytium-
At rest, the heterodimeric rel / nf - k b complex is located in the cytoplasm bound to an inhibitory factor, i k b. upon stimulation, i k b is phosphorylated and degraded, free nf - k b then translocates into the nucleus where it binds to k b site to regulate transcription
靜息時, re皿4bh聚體與抑制蛋白kbs結合,在細胞漿中保持無活性。受到刺激, ikb分子迅速磷酸化並降解,釋放nf兒b轉位入核,通過與kb位點結合調節轉錄。Confocal microscopy observation followed immune - fluorescence staining with anti - gp130 showed that gp130 could interact with tle1 at the cytomembrane region. moreover, this interaction inhibited the concentration of tle1 into nucleus
為了進一步證實上述發現,我們表達並純化了gst - gp130胞漿區融合蛋白和gst - tle1獨特性片段融合蛋白,並制備了特異性抗tle1多克隆抗體。Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素進入細胞的機理不甚明了,一般認為是rtb先與細胞膜受體結合,主要經過受體介導的內吞作用進入吞噬體,然後沿著內體、高爾基體、內質網等逆向分泌途徑,有序地運輸到內質網,最後從內質網轉位進入細胞漿,在胞漿內攻擊核糖體,從而抑制蛋白質的合成,導致細胞死亡。Gc binds to mr with higher affinity than gr. this gc - receptor interaction is also controlled at the pre - receptor level by two important factors : corticosteroid binding globulin ( cbg ) and 11 b - hydroxysteroid dehydrogenases ( 11 - hsds )
糖皮質激素與受體結合的量除與血漿中糖皮質激素水平、皮質醇結合蛋白( cbg )濃度有關外,還受到細胞內受體前糖皮質激素代謝酶? 11 -羥基類固醇脫氫酶( 11 - hsd )的調節。Mechanism of glutamate - induced inhibition of pulmonary surfactant lipid synthesis ? mda receptor ( nmdar ) antagonist mk - 801 could reverse glutamate - induced inhibition of [ 3h ] - choline incorporation in lung explants ; ? he expression of nmdar1 subtype existed in alveolar type ii epithelial cells ; ? he effect of glu on pc synthesis required l - arginine in cultured lung explants, nos activity and no production were increased significantly in lung explants with glu treatment ; and mk - 801 and nos inhibitor l - nna could block the increase of nos activity and no production induced by glu ; l - nna also could reverse the inhibition of [ 3h ] - choline incorporation induced by glu ; ( 4 ) mda content increased and sod level decreased in cultured lung explants of glu treament groups, mk - 801 and l - nna could reverse these effects ; ( 3 ) mk - 801, l - nna could block the release of ldh induced by glu
谷氨酸對肺表面活性物質脂質合成抑制的機制研究nmda受體拮抗劑mk - 801能逆轉glu所致肺組織[ ~ 3h ] -膽堿摻入減少的效應;肺泡上皮細胞有nmda受體nmdar1亞單位的表達; glu對ps脂質合成的影響依賴l -精氨酸的存在, glu可使肺組織勻漿中nos活性、 no合成量升高; mk - 801 、 nos的抑制劑l - nna均可阻斷glu所致的這些效應; l - nna可逆轉glu所致肺組織[ ~ 3h ] -膽堿摻入減少的效應; glu可使肺組織勻漿中mda碩士學位論文中文摘要含量增高、 sod水平下降。 mk七0 、 l nna能阻斷q所致的這些效應; mk80 、 l nna還能阻斷gill誘導的ldh釋放增多的效應。The pink, rounded intracytoplasmic inclusion in the giant cell of the inset at the upper right is typically seen with respiratory syncytial virus ( rsv ), a common cause for pneumonia in infants and children under 2 years of age
右上的插圖顯示的是巨細胞內的粉紅色圓形胞漿內包涵體,它在呼吸道合胞病毒( rsv )感染中很典型,在嬰兒和2歲下面的的兒童中是引起肺炎一個常見的病因。When the approach to get a direct binding molecule was proved not fruitful, attention was turned to find binding sources for the purpose of further isolating the binding protein. the first considered and also the relatively easier - obtained materials are some adhesion molecules. results showed, only n - cam 140 showed ambiguous binding
, idin砰proteina磁珠為結合反應載體,從小鼠成年全腦勻漿作為結合起始材料,以蔗糖密度梯度離心法進4行細胞亞組分分離,以sds page顯示陽性結合條帶,以westernblot確定蛋白身份。Bsp ( boyine seminal plasma ) protein is the cardinal protein in bovine sperm, which can combine with choline or phosphycholine and then adhere to the surface of sperm to promote the sperm capacitation induced by heparin and high density lipoproteins ( hdl ). moreover, bsp protein can combine with heterogeneous collagen, fibrinogen, heparin, calmoduline, igf - ii and apoa - i. bsp can also inhibit the migration of cholesterol on the sperm membrane
前言bsp ( bovineseminalplasma )蛋白是牛精漿中的主要蛋白質, bsp蛋白可以與膽堿或磷脂膽堿結合,黏附於精子表面,可促進由肝素、 hdl等誘導的獲能過程,另外bsp蛋白與不同來源的膠原、纖維蛋白原、肝素、鈣調蛋白、 igf - 、 apoa -等結合, bsp蛋白還可抑制精子胞膜上的膽固醇遷移,這些都暗示了bsp蛋白在精子胞膜的脂類代謝及調節精子的獲能以及頂體反應方面發揮重要作用。Change of free calcium ion concentration in cytoplasm of vascular endothelial cells induced by complement membrane attack complex
補體膜攻擊復合物刺激血管內皮細胞胞漿游離鈣離子濃度的變化Fig. 3 anoxia reperfusion group with the addition cerium ions : myocardial cell structure shows vague, mitochondria swell, deposits of cerium are scattered throughout the cytoplasm, some parts appear confluent
圖3缺氧再灌注加鈰組:心肌細胞結構不清,線粒體腫脹,胞漿內充滿大量的鈰沉積顆粒,有些部位融合成片。Methods : in cultured lung explants without serum, the lipid component synthesis of pulmonary surfactant was evaluated in [ 3h ] - choline incorporation ; mrna content of phosphocholine cytidylyltransferase ( cct ) in lung explants was investigated in rt - pcr ; the changes of the ultrastructure of the at ii cells were observed with electron microscope ; the expression of nmdar1 subtype was observed in immunohistochemistry staining ; nitric oxide synthase ( nos ) activity, nitric oxide ( no ) content, superoxide dismutase ( sod ) level, malondialdehyde ( mda ) content and lactae dehydroase ( ldh ) level were determined by biochemistry methods. results : 1. influence of glutamate on synthesis of the lipid component of pulmonary surfactant ? with l - arginine, glu inhibited [ 3h ] - choline incorporation with good dose - dependence and time - dependence ; ( 2 ) mrna content of cct of the glu treatment groups was decreased ; ( 3 ) glu increases the release of ldh in cultured lung explants ; ( dwith electron microscope histochemistry, glu induced the changes of the ultrastruture of at ii iv cells
方法:採用成年大鼠肺組織無血清培養,運用[ ~ 3h ] -膽堿摻入法測定ps主要脂質磷脂酰膽堿( pc )合成量; rt - pcr擴增檢測肺組織中pc合成限速酶磷酸膽堿二胞苷酰基轉移酶( cct ) mrna含量;透射電子顯微鏡法觀察肺泡型上皮細胞和ps系統超微結構的變化;免疫組織化學染色檢測glu的受體nmdar1亞單位的表達;生化測定肺組織乳酸脫氫酶( ldh )釋放量和肺組織勻漿中一氧化氮合酶( nos )活性、一氧化氮( no )生成量、超氧化物歧化酶( sod )水平以及丙二醛( mda )含量。By yeast two - hybrid assay, aes was found to interact with gp130 intracellular region through its conserved q domain. results from the yeast two - hybrid assay, gluthione s - transferase fusion protein pull - down assay and immuno - co - precipitation assay indicated that the q domain of tle1 is capable of binding gp130 intracellular domain, and the intracellular membrane proximal region of gp130 containing conserved boxl and box2 motifs seemed essential for this interaction. to investigate the consequence of this interaction, tle1 - gfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with gp130 expression vector
在通過酵母雙雜交分析確定aes通過q結構域與sp130分子胞漿區結合的基礎上,為確定tle1分子是否也能通過保守的q結構域與gp130分子胞漿區結合,我們通過pcr擴增編碼gp130胞漿區與tleq分子不同結構域的cdna ,構建了含有這些不同結構域的酵母雙雜交載體,通過酵母雙雜交分析證實: tle1分子通過其氨基端的q結構域與gp130分子胞漿區近膜段結合。“ synthesis of a large chromosome is now clearly in reach, ” said venter, who for several years led a project to identify the minimal set of genes required for survival by the bacterium mycoplasma genitalium. “ what we don ' t know is whether we can insert that chromosome into a cell and transform the cell ' s operating system to work off the new chromosome
過去幾年來,凡特領導一項計畫,要找出讓生殖道?漿菌生存所需的最少基因有哪些,他說:顯然要合成更大的染色體是指日可待的事情,但我們不知道是否可以把那染色體塞入細胞中,且是否能夠改變細胞的操作系統,讓它去表現新的染色體。分享友人