胞體樹突 的英文怎麼說
中文拼音 [bāotǐshùtū]
胞體樹突
英文
cytodendrite-
Dendritic cells are characterized by their ability to efficiently present antigen, and are uniquely equipped to stimulate naive t cell responses. immature dendritic cells acquire antigens from throughout the peripheral body, then migrate to t - lymphocyte - dependent areas of lymph nodes. thus, dendritic cells act as bridges, operating at the interface of innate and acquired immunity
作為機體免疫系統中功能最強的專職性抗原提呈細胞( antigen - presentingcells , apc ) ,樹突狀細胞( dendriticcells , dc )能高效地攝取、加工處理和提呈抗原,具有較強的遷移能力,並能顯著地激活初始型t細胞以啟動t細胞免疫應答反應,此外, dc與b細胞以及nk細胞等也存在著相互作用,可見, dc在連接天然免疫和獲得性免疫之間起著非常重要的作用。However, the advance of intracellular labeling techniques enables us not only to visualize more complete dendritic arbor for qualitative analysis, but also to examine the relation between changes in the dendritic arborization and the evoked fast postsynaptic curents - 3 - ( fpscs ) in the same neurons during the postnatal development the aim of this study was to systematically examine the postnatal changes in the configuration of fpscs evoked by the focal stimulation of the stratum radiatum of the ca1 region, and the relationship between the dendritic arborization and evoked fpscs in the rat hippocampal ca1 pyramidal neurons using whole - cell blind patch recording technique combined with biocytin intracellular labeling during the postnatal development ( postnatal day 2 - 70, p2 - p70 )
但是,細胞內染色技術的進步使我們不僅能觀察到更完整的樹突分支來用於定性研究,而且也可以在同一神經元上研究在發育過程中樹突分支的變化與誘發的快突觸后電流( fastpostsynapticcurrents , fpscs )之間的關系。因此,本研究應用盲法腦片膜片鉗記錄並結合biocytin細胞內染色方法,對發育過程中(生后2 70天)局部刺激大鼠海馬ca1區輻射層在錐體神經元誘發的fpscs的成分變化,以及ca1錐體神經元的樹突分支與誘發的fpscs的關系進行了較為系統的研究。To date, there are few successful cases in the immunotherapy of cancer patients. the reasons for this have been the limited availability of tumor - associated antigens ( taa ) and the inability to deliver such antigens in a manner that renders them immunogenic and activates t cell responses in patients with cancer
樹突狀細胞( dendriticcells , dc )是抗原提呈細胞( antigenpresentingcells , apc )的一個特殊群體,雖然在體內數量很少,但其分佈十分廣泛,是體內功能最強大的apc 。Study on immunoreaction induced by dcs loaded with hepatocarcinoma antigen peptide in vitro
樹突狀細胞負載肝癌抗原肽疫苗體外誘導特異性免疫學反應的研究Effects of cytokine combinations and calcium ionophore on differentiation of dendritic cells from acute myeloid leukemia cells
組合性細胞因子與鈣離子載體誘導急性髓系白血病細胞向樹突狀細胞分化中的作用Reconstitution dynamics of plasmacytoid and myeloid dendritic cell precursors after allogeneic hla mismatched haploidentical hematopoietic stem cell transplantation
單倍體相合造血幹細胞移植后外周血樹突細胞重建Myeloid dendritic cells, which contribute to an immunologic synapse responsible for activation of the adaptive immune system, are abundant within muscle in inclusion body myositis and polymyositis
作用於免疫突觸反應、活化適應性免疫應答的髓樣樹突狀細胞在包涵體肌炎和多發性肌炎中大量存在。Part i the electron microscope study of the synaptic connections of pan albumin - like immunopositive structure in the second - / third - nuclei on the central pathway of the trigeminal proprioceptive sensation of the rat the present study examined that the synaptic connections of pv - like immunoreactive ( pv - li ) neuronal cell bodies, fibers and terminals on the second - / third - order nuclei of this pathway by using electron microscopic immunohistochemical method
結果如下: 1在vodln l肚區及帶狀區(包括vpdm 、 vsllp cl 、 ado 、 avm )內均可觀察到大量的pv樣陽性神經元的樹突和軸突終末, pv樣陽性胞體較少。Fos + / th + / gfap + and fos + / vp + / gfap + triple labeled n - asc could be found in the mvz, pvn and son respectively ; ( 2 ) under electronic microscope, the astrocytic processes connected closely with the dendrites or axons of the neurons, where the bilateral membranes became thick. we call transiently it electron - dense areas ( edas ). the number of edas increased remarkably following hyperosmotic stimulation ; ( 3 ) when trace retrogradely, wga - hrp was microinjected into the unilateral son, pvn or nucleus of solitary tract ( nts ) respectively using the stereotaxic method, the n - ascs formed by the neurons triple - labeled with hrp / fos / th ( or vp ) and astrocytes labeled with gfap could be found in the mvz, son and pvn respectively ; ( 4 ) after being treated with heperosmotic nacl solution, intracellular calcium concentration in cultured hypothamic neurons and astrocytes increased and then decreased
腦內gfap陽性結構也明顯增多,其分佈與fos陽性細胞分佈基本一致,表現為胞體肥大、突起粗長; ast緊密包繞在神經元周圍形成神經元- ast復合體( n - asc ) ;在mvz 、 pvn和son三重免疫組化染色切片上可見到fos + th + gfap +第四軍醫大學博士學位論文和fos vp gfap三重標記asc ; ( 2 )免疫電鏡下son內星型膠質細胞突起與神經元樹突或軸突之間接觸部位出現增厚的膜結構一電于緻密區( edas ) ,高滲刺激后數量明顯增多: ( 3 )將們個mp注入大鼠一側n卜、卜卜或孤束核( ws ) ,分別在延髓內臟帶( mvz ) 、 so和pvn內出現fos hrp th 、 fos hrp八p三重標記神經元和gfap陽性標記ast形成的n asc ; ( 4 )高滲刺激使培養神經元和ast內鈣水平先升高后降低,最後維持在比高滲刺激前稍高的靜息鈣水平上。Hi our study, dendritic cells ( dcs ) were derived from the cultivation of peripheral blood monocytes in vitro successfully. then to observe whether dcs transfected with carcinoembryonic antigen ( cea ) - vaccinia recombinant virus ( rv - cea ) can induces cytotoxic t lymphocyte - mediated cea - specific immunity in vitro
體外成功地完成了cd14 +單核細胞來源的樹突狀細胞( dc )的培養,並進一步研究人癌胚抗原重組痘苗病毒( rv - cea )轉染dc后體外誘導的cea特異性細胞免疫。In vitro experiment research of the anti - glioma activity of the glioma vaccine made from dendritic cell
樹突狀細胞瘤苗抗腦膠質細胞瘤作用體外實驗研究Its salient features are its ability to open to ionic current when stimulated on its dendrites ; to sum the incoming potentials in its cell body and to emit an action potential down its atomic part, if the potential accumulated is high enough
其顯著特點為:當加刺激於其樹突上時能開啟離子電流;能將進入細胞體中的電位相加,如積累的電位足夠高,則發出一動作電位(沖動) 。Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用, t細胞在發揮抗瘤效應(分泌細胞因子和直接殺傷)之前必須先經過活化,體內專職抗原提呈細胞( apc )細胞並使其活化,樹突狀細胞( dendriticcell , dc )為t細胞的激活提供雙重信號, t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后,通過tcr - cd3復合體傳遞抗原特異性識別信號(第一信號) ,以cd28為主的t細胞表面輔佐分子識別dc表面b7分子,傳遞非特異性協同刺激信號(第二信號) ,在機體抗腫瘤免疫應答中處于核心地位。Suss g, shortman k. a subclasss of dendritic cells kills cd4 t cellsvia fas / fas2ligand induced apoptosis [ j ]. j ex p med, 1996, 183 ( 4 ) : 178921796
張建芳,于文彬,徐修禮,等.樹突狀細胞誘導高聚金葡素刺激的淋巴細胞體外高效特異性殺瘤作用[ j ] .細胞與分子免疫學雜志, 2001 , 17 ( 2 ) : 1492151Effects of transcranial magnetic stimulation on learning and memory, morphology and ultrastructure of contralateral hippocampal ca3 pyramidal neurons in rats with cerebral infarction
經顱磁刺激對腦梗死大鼠學習記憶與健側海馬錐體細胞樹突和突觸結構的影響Methods employed to prepare vaccine include rumor cells genetically modified with cytokines, costimulatory molecules and tumor antigenic peptides, dendritic cells ( dc ) primed with tumor antigens in vitro or genetically modified with tumor antigens, or fusion of tumor cells with antigen presenting cells ( apc )
現有的比較受到關注的制備腫瘤疫苗的方法有各種細胞因子、共刺激分子、腫瘤抗原肽等基因修飾的腫瘤細胞疫苗;體外抗原致敏的或腫瘤抗原肽基因修飾的樹突狀細胞疫苗;腫瘤細胞與抗原遞呈細胞融合疫苗等。The study in vitro of anti - hepatoma immunity induced by dendritic cells pulsed with the lysate of autologous hepatoma cells
自體肝癌細胞裂解物致敏的樹突狀細胞誘導抗肝癌免疫的體外研究Allogeneic tumor vaccine produced by electrofusion between osteosarcoma cell line and dendritic cells in the induction of antitumor immunity
異體樹突狀細胞融合瘤苗抗骨肉瘤的免疫效應實驗Research on necessity and feasibility of china municipal bond issue
樣受體及與樹突狀細胞的分化和信號轉導的研究進展Methods an immunohistochemical staining method was used. results nk3 receptor - li was localized in somatic and dendritic profiles in the most parts and in neuropil in a few regions of the mouse central nervous system
應用免疫組織化學染色方法對小鼠中樞系統內nk3受體的分佈進行了觀察,結果表明:在小鼠中樞神經系統的絕大部分區域, nk3受體樣免疫陽性產物位於胞體和樹突上,少部分區域位於神經氈( neuropil )內。分享友人