脫氫皮質酮 的英文怎麼說

中文拼音 [tuōqīngpízhítóng]
脫氫皮質酮 英文
dehydrocorticosterone
  • 脫 : Ⅰ動詞1 （脫落） cast; shed; drop; fall off 2 （取下; 除去） take off; strip; cast off 3 （脫離） ...
  • 氫 : 名詞[化學] （氣體元素） hydrogen （h）
  • 皮 : Ⅰ名詞1 （人或物體表面的一層組織） skin 2 （皮革） leather; hide 3 （毛皮） fur 4 （包在外面的一層...
  • 質 : Ⅰ名詞1 （性質; 本質） nature; character; essence 2 （質量） quality 3 （物質） matter; substance;...
  • 酮 : 名詞[化學] （有機化合物的一類） ketone; alkone; ket-; -one
  • 皮質 : [生理學] cortex
  1. The principal adrenocortical products are aldosterone, cortisol and dehydroepiandrosterone sulphate.

    腎上腺皮質的主要產物為醛固酮、皮質醇和脫氫異雄酮硫酸鹽。
  2. The 11 - hsd1 expression in the fetal brain also gradually increases with gestational age at late gestation and continues to increase in the hippocampus after birth until the 15th postnatal day, which shows a pattern very similar to th secretion. furthermore, previous data show injection of thyroxine ( t4 ) to normal newborn rats up - regulates gr expression in the hippocampus. these data suggest that the role of th in neural development may be partially ( if not all ) accomplished through regulating gc ' s activity

    在海馬結構， 11 - hsd1與gr共存於同一海馬神經元內，主要呈現還原酶的特性，能使無活性的11 -脫氫皮質酮（ a ）可的松（ e ）轉化為有活性的皮質酮（ b ）皮質醇（ f ） ，從而提高組織局部的糖皮質激素濃度，這樣， 11 - hsd1的存在就為親和力較低的gr發揮作用提供了前提條件。
  3. Which may provide the molecular basis for the inberine regulation of ll p - hsdl expression by glucocorticoids. secondiy, the regulation of l l 9 - hsdl expression and redutase activity by glucocorticoids was investigated in the primny cultured human chorionic trophoblast

    整個妊娠過程中胎盤11 - hsd活性以氧化酶為主，使母體gc在進入胎兒循環前大部分被轉化為無活性的17 -羥- 11 -脫氫皮質酮，保證胎兒正常發育所需的激素濃度。
  4. The co - expression of l l6 - hsd1 and gr in the saxne chorionic trophoblast suggests possible intrcrine achons ofglucoconicoid generated by l l6 - hsdl within the cells. 2. ewe radiomctric conversion assay showed that trctrient of the cells with the synthetic glucocorticoid - - dexarnethasone ( l0 - ' m ) for 24h increased the conversion of conisone to cortisol, and thes increase was blocked by the gr antagonist ru486

    雙標免疫組織化學染色結果顯示11p hsdi和gr共存於同一個滋養層細胞，提示在體內無活性的gc代謝產物?一17羥d脫氫皮質酮經11p hsdi還原活化后可以直接與同一個細胞內的gr結合，即以內在分泌（ intracrine ）形式發揮作用
  5. L l6 - hsd2 is localized to the sppytiotrophoblast of the placenty providing a fimctional barrier protecting the fetus from matemal glucocorticoids. a sequence resembling glucocorticoid response element ( gre ) has been identified in the promoter region of the human l l0 - hsdl gene. glucocorticoids have been shown to induce the expression of 11p - hsdl in the hippomus in vitro " whereas controversial results were obtained in the hepatocyte

    體內至少存在兩型11 - hsd ，在細胞完整的狀態下， 11 - hsd1主要為還原酶，它活化gc的代謝產物17 -羥- 11 -脫氫皮質酮（嚙齒類為脫氫皮質酮）為有活性的皮質醇（嚙齒類為皮質酮） ，而11 - hsd2為氧化酶，它催化皮質醇為無活性的17 -羥- 11 -脫氫皮質酮，因此11 - hsd1加強gc的作用，而11 - hsd2減弱gc的作用。
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