腫瘤免疫原性 的英文怎麼說

中文拼音 [zhǒngliúmiǎnyìyuánxìng]
腫瘤免疫原性 英文
immunogenicity of tumor
  • 腫 : Ⅰ名詞（隆起處） swelling Ⅱ動詞（突起） swell; be swollen
  • 瘤 : 名詞（瘤子） tumour
  • 免 : Ⅰ動詞1 （去掉;除掉） dismiss; relieve; remove 2 （避免） avoid; escape; avert 3 （免去） excuse s...
  • 疫 : 名詞（瘟疫） epidemic disease; pestilence
  • 原 : Ⅰ形容詞1 （最初的; 原來的） primary; original; former 2 （沒有加工的） unprocessed; raw Ⅱ動詞（原...
  • 性 : Ⅰ名詞1 （性格） nature; character; disposition 2 （性能; 性質） property; quality 3 （性別） sex ...
  • 腫瘤 : tumour; core （綿羊體內的）; neoplasm; phyma
  1. The progress in research of swainsonine immunogenicity and anticancer - activity

    苦馬豆素的免疫原性及抗腫瘤研究進展
  2. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  3. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  4. If pericarditis is suspected, the history should address exposure to infectious agents, connective tissue and immune diseases, and previous diagnosis of neoplasia

    當懷疑有心包炎時，病史應注重感染原接觸史，結締組織和免疫性疾病史和以往的腫瘤診斷史。
  5. Tumor antigens of hepatocellular carcinoma and its specific cellular immunity

    肝癌的腫瘤抗原與特異性細胞免疫
  6. It delivers the false ? folding peptides for presentation to proteasomes in normal cells, while in tumor cells it acts as main tumor - resistant antigen, inducing specific immune response. recent research found that grp94 also relates with cell cycles, differentiation and apoptosis

    此外發現它還具有抗原提呈作用，在正常細胞中參與折疊錯誤蛋白到蛋白酶體的提呈；在腫瘤細胞中作為主要的腫瘤排斥抗原，引發針對該腫瘤細胞的特異性免疫反應。
  7. Objective : in most t eel ] malignancies, there are t cell receptors ( tcr ) expressed on the surface of the tumor cells

    目的：大多數t細胞腫瘤表面有tcr獨特型抗原，可作為腫瘤特異性抗原用於免疫治療。
  8. Unfortunately, tumor cells can secrete immunosuppressor factors ( such as il - 10, tgf - p, vegf ) to interfere with dc maturation and function. to overcome tumor - mediated inhibition of dc maturation and function in vivo, immunopotentiating cytokines ( such as il - 7, il - 12 ) were used for gene - modification of dc, which has proven to be an efficient way to treat cancer in animal models

    雖然有直接瘤內注射dc誘導抗腫瘤免疫效應的報道，但腫瘤局部往往是一個處于高度免疫抑制狀態的微環境，腫瘤細胞分泌的可溶性介質（如ill 、 tgf卜vegf等）能抑制dc的分化成熟，下調dc表面共刺激分子的表達和iliz的分泌，從而抑制dc的抗原提呈功能，亦對t細胞功能有顯著的抑制作用。
  9. Sj grens syndrome, radiotherapy of oral facial maxillorary tumor and allergic reaction of medicine or auto alleray could lead to lesion of the function of smg, which is very difficult to treat. however, the advancement of tissue engineering can change it

    舍一格林綜合癥、口腔頜面部腫瘤術後放療及藥物過敏或自身免疫性疾病等多種原因造成的涎腺功能嚴重損害在臨床上較為常見，治療問題十分棘手。
  10. Macrophage is a kind of immune cell as well as accessory cell. it can function as antiinfection, anticancer, immune response and immunoregulation by phagocytosis, antigen presentation, cytokines secretion, lymphocyte activation, reactive oxygen and no production. it ' s an important part of body immune system

    巨噬細胞（ macrophage ）既是免疫細胞，又是輔佐免疫應答細胞，可通過吞噬、抗原呈遞、分泌細胞因子、激活淋巴細胞和產生活性氧、 no等作用而行使抗感染、抗腫瘤、免疫應答和免疫調節作用，是機體免疫系統的重要組成部分。
  11. Chitin and its derivative can strengthen the function of resisting on the microorganism of many kinds of etiologies of organism through regulating the function of immune system of organism, have effect of suppressing to tumour cells, such as mouse metha fibrosarcoma, s180 tumour, mm44 entity tumour and lewis lung cancer, etc. most of these investiments, however, were carried out through in vivo experiments, and research on stimulating function of oligochitosan to one particular part of immune system was very few

    幾丁質及其衍生物通過調節機體免疫系統功能，能增強機體對多種病原微生物的抵抗作用，對實驗性小鼠metha纖維肉瘤、 s180腫瘤、 mm44實體瘤及lewis肺癌等腫瘤細胞的生長具有抑制作用。研究表明殼寡糖具有免疫調節作用，有抗感染及抗腫瘤活性。但眾多研究以動物整體實驗為主，關于殼寡糖對免疫系統某一特定環節直接作用的研究較少。
  12. Study of immunity of epitope of tumor special antigen displayed on a filamentous bacteriophage

    噬菌體展示腫瘤異性抗原表位的初步免疫活性研究
  13. Filamentous bacteriophage displayed tumor - specific antigen epitope mage - a1 induced cellular immune in mice

    展示腫瘤特異性抗原表位的噬菌體在小鼠體內引起的細胞免疫變化
  14. These conventional approaches cannot be selectively targeted to the tumor cells and completely eradicate them, this may account for the development of recurrence and metastasis of gastric cancer due to the existence of residual tumor cells ; in addition, as to some kinds of conventional approaches, such as chemical therapy, their tumoricidal effects also could cause damage to some other normal tissues / cells and undermine the function of immune system in patients with gastric cancer

    目前，臨床上的?些常規方法，包括外科手術的、化學的及物理的治療手段，對絕大多數中晚期胃癌的療效均不理想。其原因在於這些常規方法對癌細胞缺乏選擇性，並不能特異性地殺傷癌細胞，勢必造成殘存癌細胞引起的腫瘤復發和轉移。某些常規方法，如化療，在殺傷癌細胞的同時，也會造成機體正常組織的損傷並削弱機體的免疫機能。
  15. When the body suffered from malignancy, on the one hand, tumor restrained cell immunity function, antibody ' s production and the body ' s immunity effect through inducing restraining t cell, so it accelerated tumor ' s growth, on the other hand, tumor induced body fluid restrained gene, which prevented t cell and nk cell from killing tumor and restrained lymphocyte to mitotic multiplication reaction, indeed it accelerated tumor ' s growth

    當機體一旦患上惡性腫瘤后，一方面腫瘤通過誘導抑制性t細胞，抑制細胞免疫功能及抗體的產生，抑制機體對腫瘤的免疫效應，從而使腫瘤逃逸機體的免疫監視，促進腫瘤的生長。另一方面，腫瘤通過誘導體液抑制因子阻止t細胞和nk細胞的等對腫瘤的殺傷作用，抑制淋巴細胞對有絲分裂原的增殖反應，甚至促進腫瘤的生長。
  16. This article describes one primarily adrenal - dysfunction patient with severe tbi who had no evidence of present or prior adrenal autoimmune disease, infection, hemorrhage, or malignancy

    本文報告一位無腎上腺自體免疫病、感染、出血及惡性腫瘤病史的嚴重腦外傷患者發生原發性腎上腺功能不全，呈現腦外傷引發原發性腎上腺功能不全的狀況。
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