致癌基因 的英文怎麼說
中文拼音 [zhìáijīyīn]
致癌基因
英文
oncogene致癌基因學說 oncogene theory-
Earlier this year, a study by gerd pfreier of beckman research institute pointed out the specific substance causing cancer in cigaret smoke, whose target was some parts of gene which, people discovered, played a prominent role in some cancers
而今年早些時候,貝克曼研究所的格爾德?普法伊費爾所作的一項研究確切地指出了卷煙煙霧中固有的致癌物,這些致癌物襲擊的目標是一種基因的某些部分,人們已經發現,這種基因在一些癌癥中很突出。From different points of view of the epidemiology, cytogenetics, molecular biology, experimental pathology and preventive medicine, this study revealed and proved that the genotoxicity and carcinogenesis existed in the drinking pond water in the high incidence area of live cancer in guangxi, indicated the feasible preventive and interruptive methods, too
從分析流行病學,細胞遺傳毒理學、分子生物學、實驗病理學和預防醫學的不同角度,揭示和論證了廣西某肝癌高發區居民飲用塘水的基因毒性和致癌性,提出了切實可行的預防和阻斷措施。Nci - h1155, a human non - small - cell lung cancer line, was employed in a paclitaxel - dependent synthetic lethal screen designed to identify gene targets that specifically reduce cell iability in the presence of otherwise sublethal concentrations of paclitaxel
Nci - h1155作為一種人類非小細胞肺癌的種株,可運用其在依賴紫杉醇殺傷性藥物合成過程中設計鑒別出靶基因,從而特異性減少未達到殺傷性致死量的紫杉醇藥物作用后腫瘤細胞仍存活的數量。Therefore, it is important to study the profiles of gene expression, which will help understand the global cellular stress responses to chemical carcinogens, and further elucidate the mechanisms of nontargeted mutagenesis
所以,從整體上研究烷化劑作用后細胞基因表達譜改變,對于了解化學致癌物誘發的哺乳動物細胞應激反應的全貌和揭示非定標性突變的發生機制具有非常重要的意義。In our laboratory, a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0. 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0. 2m mnng for 2. 5h, then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture. we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells. this kind of mutation did not occur immediately after mnng exposure
我們實驗室曾用一特殊的突變檢測系統,直接證明dna損傷劑可在哺乳動物細胞誘發非定標性突變:首先用低濃度( 0 . 2 m )的短壽烷化劑mnng (半壽期為1 . 1hr )處理細胞2 . 5h后,繼續培養24h ,將重組有用作突變檢測的靶基因supftrna基因的穿梭質粒pz189轉入細胞復制,發現在未受致癌物直接攻擊的穿梭質粒中有較自發突變率高5倍以上的靶基因突變。With hazards everywhere, plus the complications of genetic predisposition and age, it is hard for comeone to work out his actual risk of developing either cancer or metabolic syndrome
由於致病的因素相當常見,再加上基因上免疫缺陷和年齡這類因素的復雜性,確定患上無論是癌癥還是代謝綜合病癥的實際風險就非常困難。Biological evaluation of medical devices - part 3 : tests for genotoxicity, carcinogenicity and reproductive toxicity included in ansi aami iso 10993 - 1993 : a collection
醫療器械的生物評定.第3部分:基因毒性致癌作用和生殖毒性的測試The genome project will take a lot of time and expense to actually benefit people. compared to this, the mrt is easier and cheaper. cancer - causing materials can be tracked also
基因工程需耗費很多時間和財力才能利益人類與之相比, mrt既容易又經濟,而且還可以追蹤致癌因素。Anything from cosmic rays to radiation to diet may activate a dormant oncogene, but how remains unknown
任何東西,從宇宙射線到輻射,以至日常飲食,都可能激活潛伏的致癌基因,但如何激活的,仍然不得而知。A gene that causes the transformation of normal cells into cancerous tumor cells, especially a viral gene that transforms a host cell into a tumor cell
致癌基因導致正常細胞轉變為癌變細胞的基因,尤其是一種把寄主的細胞變為腫瘤細胞的病毒基因The exact mechanisms involved are still mysterious, but the likelihood that many cancers are initiated at the level of genes suggests that we will never prevent cancers
從宇宙射線到輻射到飲食,任何東西都有可能激活沉睡中的致癌基因,但激活的方式尚不得而知。The researchers make great progress in the early 1970s, when they discovered that oncogenes, which are cncer - causing genes, are inactive in normal cells
譯:研究者早在70年代的時候取得了很大的進展,當時他們發現致癌基因,即那些可以引起癌癥的基因,在正常細胞中是不活動的。O " the genome research centre and its collaborators are already using the hapmap to look for genes for schizophrenia, diabetes, osteoporosis and lumbar disc degeneration in specific genomic regions. we are now planning to conduct genetic studies on a genome - wide scale for these diseases as well as others such as breast and colorectal cancers.
-基因研究中心及一同合作的科研人員正利用hapmap尋找部分基因組區域內引致精神分裂癥、糖尿病、骨質疏鬆癥及椎間盤退化等疾病的基因。除此之外,我們正計劃就這些疾病作出全基因組的研究,有關研究還包括了其他病癥如乳癌、直腸癌等。The human genome project has already aided scientists in discovering a mutation that causes a deadly type of skin cancer and accelerated the search for genes involved in diabetes, leukemia and childhood eczema
人類基因工程已經幫助科學家們發現了一種致命皮膚癌的突變原因,並加速了人類對糖尿病,白血病和小孩濕疹的基因研究。Alterations in dna methylation, an important regulator of gene transcription, lead to cancer
對調節基因轉錄起重要作用的dna甲基化的異常將導致癌癥的發生。The us national cancer institute says on its website that the main chemical in stevioside can be converted in a laboratory into a substance that alters genes. further study is needed to determine whether the sweetener can cause cancer, it says
美國全國癌癥研究會在其網站上指出,甜葉菊甙的主要化學成分在實驗室可以被轉化為能改變基因的物質,而要確定這種甜味劑能否導致癌癥還需進一步研究。The us national cancer institute says on its website that the main chemical in stevioside can be converted in a laboratory into a substance that alters genes. further study is needed to determine whether the sweetener can cause cancer it says
美國全國癌癥研究會在其網站上指出,甜葉菊甙的主要化學成分在實驗室可以被轉化為能改變基因的物質,而要確定這種甜味劑能否導致癌癥還需進一步研究。Occurrence of liver carcinoma is a synergistic action by multiple factors which include virus infection, carcinogen, oncogene activation, anti - oncogene inactivation, liver cell apoptosis, failure of proliferation regulation and so on
肝癌的發生是一個多因素協同作用的過程,這個過程中包括病毒感染、致癌物的作用、癌基因的激活和抑癌基因的失活、肝細胞的凋亡和增殖調節失控等多因素多環節。Rapl belongs to ras superfamily of small gtp - binding proteins, which is considered to control cell growth, differentiation and survival. rapl was regarded as an antagonist of ras because it can revert the phenotype of oncogene ras transformed cells. recent researches show that rapl has its ras - independent functions in a variety of cellular systems besides its effect as an antagonist of ras
Rap1除具有逆轉原癌基因ras激活突變體所導致的細胞形態改變而被認為是ras的拮抗物外,最近的研究還發現rap1在一系列的細胞系統中有獨立於ras之外的功能,如控制與細胞粘附有關的事件等,因而成為研究的熱點。Collecting large sample groups of genetic information, together with data on lifestyle choices and genealogy, is aimed at enhancing the understanding of the genetic causes of hereditary diseases such as cancer, heart disease, diabetes and certain mental problems
大規模搜集基因信息樣本、生活方式選擇和血緣數據,目的是為了提高對一些遺傳類疾病致病基因的理解,包括癌癥、心臟病、糖尿病和一些特定的精神疾病。分享友人