轉錄抑制 的英文怎麼說

中文拼音 [zhuǎnlùyìzhì]
轉錄抑制 英文
transcription inhibition
  • 轉 : 轉構詞成分。
  • 錄 : Ⅰ名1 （用做記載物的名稱） record; register; collection; selections 2 （姓氏） a surname Ⅱ動詞1 （...
  • 抑 : Ⅰ動詞（向下按; 壓制） restrain; repress; curb Ⅱ連詞[書面語]1 （表示抉擇） or 2 （表示轉折） but3 ...
  • 制 : Ⅰ動詞1 （製造） make; manufacture 2 （擬訂; 規定） draw up; establish 3 （用強力約束; 限定; 管束...
  • 轉錄 : [電學] transcribe; transfer; [聲學] mixing; rerecording; [生物學] transcription; duplicating轉錄...
  • 抑制 : 1 （控制） restrain; control; check; hold up; curb; stop; repress; bridle; choke; prehension; sup...
  1. At rest, the heterodimeric rel / nf - k b complex is located in the cytoplasm bound to an inhibitory factor, i k b. upon stimulation, i k b is phosphorylated and degraded, free nf - k b then translocates into the nucleus where it binds to k b site to regulate transcription

    靜息時， re皿4bh聚體與抑制蛋白kbs結合，在細胞漿中保持無活性。受到刺激， ikb分子迅速磷酸化並降解，釋放nf兒b轉位入核，通過與kb位點結合調節轉錄。
  2. Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ), and the notch ic translocates to the nucleus and binds to rbp - j, the mammalian homolog of su ( h ), to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ), hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues

    它通過其識別序列（ cogtgggaa ）結合於受調控基因的啟動子區，在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。在沒有n 。 tch胞內段的情況下， rbpj可與包含sm盯（ silencingmediatorforretlnoldandthyroidhormonereceptor ）和組蛋白去乙酞化酶的轉錄輔助抑制復合物結合，當notch信號被激活時； rbpj可與n 。
  3. The tumor cells transfected with restin are arrested in gl phase and the cell proliferation is inhibited. it implies that restin may be correlated to cell cycle regulation. other data showed that the necdin, a homolog of restin, could suppress cell growth by interacting with transcription factor e2f1 and p53

    而與restin的同源蛋白的necdin ，可以與細胞周期促進蛋白sv40大t抗原、腺病毒eia 、轉錄因子ezfi等相互作用，抑制細胞生長;也可以和轉錄因子p53作用參與生長抑制和抑制p53誘導的細胞凋亡。
  4. Mint ( msx2 - interacting nuclear target protein ) can interact with rbp - j and msx2 ( the murine homologue of drosophlia muscle - segment homeobox ), and represses their transcription activation activity

    進一步的研究表明mint可以與n成ch受體的胞內段競爭結合rbp j ， n而抑制rbp刁的轉錄激活作用。
  5. Intense analyses of hiv reverse transcriptase have led as well to improved versions of a class of reverse transcriptase inhibitors that do not resemble nucleosides

    針對hiv反轉錄酶的深入分析，更產生了一批與核苷類不同但效果更好的反轉錄酶抑制劑。
  6. Curcumin has been shown to induce a wide variety of tumor cells by several mechanisms, mainly including modulation of the expression of oncogenes and cancer suppressor genes, down - regulation the activation of transcription factors, via many signal transduction pathways, and the modulation of cell cycle. provides an overview of domestic and international apoptosis mechanisms of malign tumor cells induced by curcumin in order to better explore and open up new avenues of cancer treatment

    姜黃素能夠誘導多種腫瘤細胞系凋亡，其機制主要是調控癌基因和抑癌基因，下調多個轉錄因子活性，通過多種信號轉導途徑，誘發細胞周期停滯而誘導細胞凋亡.對近年來姜黃素誘導細胞凋亡的機制進行綜述，以便更好地探求和開辟治療惡性腫瘤的新途徑。
  7. The activity of apx was also decresed after sa and vd - toxin treatment. the activity of cat was decreasded more obviously. in the vd - toxin infected arabidopsis, no also restrained the activity of cat and decreased the level of cat3 mrna. the results suggested that h2o2 acted as a signal to involve the defense reactions which is induced by sa and no in arabidopsis

    No在毒素與擬南芥的互作過程中也表現出對cat的抑制作用，結果表明， h _ 2o _ 2可能作為信號分子參與了sa和no調控的擬南芥的防衛反應， sa和no或許在轉錄和蛋白水平上通過對cat的抑制作用而促進h _ 2o _ 2的積累。
  8. By means of plant genetic engineering, foreign insects resistance gene can be transferred into plant cell. we cloned the cpti gene and transferred it into mustard by agrobacterium - mtdi & ted transformation method. and obtained the transgenic mustard plants. the main results are as follows : 1. isolation of cpti gene total rna was isolated from cowpea seedss cotyledons and leaves. the cpti gene fragment was amplified by rt - pcr using sequences of its two sides as primers

    本實驗是利用植物基因工程獲得抗蟲的轉基因芥菜植株，結果如下： 1豇豆胰蛋白酶抑制劑基因的分離分別提取豇豆種子、子葉及葉片的總rna ，逆轉錄成cdna 。以豇豆胰蛋白酶抑制劑基因兩端的序列為引物，用rt - pcr的熱啟動方法從上述cdna中擴增出目的基因片斷。
  9. The ie 180 mutant combined with two special protein binding - sites and inhibited the promoter transcription. accidentally in the approach showed that the plasimd pcdna3 show as activator to sv40 and cmv early promoter. the result is acquired by instantaneous transinfect

    這說明不同的ie180突變體，對于sv40啟動于這類在轉錄起始位置一側只有一個「 5 』 atcgt 3 』 」特徵蛋白質結合序列的11類基因啟動于，可分別表現出抑制活性與激活性。
  10. The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser ctcf, and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction, cell - cycle control, chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions

    鑒定出的蛋白包括多個與轉錄調控相關的鋅指蛋白，如鋅指蛋白198 、 263 、 14 、 224 、 zf6 、轉錄抑制因子ctcf樣蛋白、幻肚pple樣鋅指蛋白等:兩個含金屬蛋白酶結構域和整合素結合結構域的家族成員adam28和adam17 ;兩個整合素家族成員pz整合素和含十個egf樣結構域的整合素（ tied ） ;與細胞信號轉導通路有關的蛋白;與細胞周期調控有關的蛋白;與染色體重塑和基因轉錄抑制有關的蛋白;細胞骨架蛋白以及其他功能未明的蛋白等。
  11. To inhibit retroviruses interacting with the cellular proteins

    抑制與細胞蛋白質相互作用的（腫瘤）逆轉錄病毒。
  12. In eukaryotes it may bind to proteins in a transcription complex to inhibit its action, or it may bind to a transcription factor

    在真核生物中，它可能與蛋白質結合形成一種轉錄復合體，抑制轉錄作用，或與轉錄因子結合在一起。
  13. At last, the related proteins and genes in meiosis are activated through a series of signal proteins, c - myc is maybe one of the target proteins in the c - kit / scf signal transduction system. it activates or suppresses the target genes in forms of myc - max, myc - myc, max - max, max - mad or max - mxil

    Myc蛋白可能作為c - kit / scf信號轉導系統的靶蛋白之一，以同源二聚體與max或mxil形成異源二聚體作用於靶基因的特有序列，激活或抑制靶基因的轉錄活性。
  14. Reverse transcriptase inhibitors rtis

    抑制逆轉錄酶
  15. Kyot2 lacked two lim domains from the c terminus and had a frameshift in the last exon, creating the rbp - j - binding region in the c terminus. kyotl had a negligible level of interaction with rbp - j. the binding site of kyot2 on rbp - j overlaps those of ramic and kyot2 repressed the rbp - j mediated transcriptional activation by ramic by competing with them for binding to rbp - j

    在肌肉母細胞系czc12內過表達kyoth時可阻斷轉錄激活物notch胞內區或ebnaz對rbp依賴性啟動子的轉錄激活作用，這種阻斷作用呈劑量依賴性，提示kyoth可與notch胞內區或ebnaz競爭rbp j上的結合位點，從而抑制二者的轉錄激活活性
  16. Recent data have demonstrated that the tails of histones h3 and h4 greatly reduce the speed of transcript elongation through a nucelosome, and tail acetylation suppresses this effect

    近來研究表明組蛋白尾部尤其是h3 、 h4四聚體的尾部強烈影響通過核小體的轉錄延伸速率，而尾部的乙酰化修飾可抑制這種影響。
  17. It is show the mutant consists of a nuclei binding site and dna - binding domain is enough to negative regulation. a report plasmid pcat that we constructed has a cat gene expressed by a cmv early promoter

    （ 465 1079氨基酸段）對sv40啟動子明顯的抑制活性，因為它只包含dna結合域和核結合位點，說明發揮轉錄抑制功能的關鍵是ie180的dna結合域。
  18. " this is inhibits the reading. ribosomes need single - strand rna in order to start, " says gerhart wagner, professor of procaryote microbiology at uppsala university

    烏普薩拉大學的原核微生物學家瓦格納教授說， 「這是一種抑制性的轉錄活動。核糖體需以單鏈rna為翻譯轉錄模板」 。
  19. These results indicated that aes might function as an antagonist of tle by binding with tle and inhibit the translocation of tle into nucleus

    提示aes可能通過抑制tle進入胞核及形成四聚體而對tle的轉錄抑制功能起桔抗作用。
  20. These results indicated that molecules of tle family might play a role in gp130 signaling. the amino - terminal regions of aes and tle are highly homologous, both contains q ( glutamine ) domain

    已知tle可通過q結構域形成四聚體，而且四聚體的形成對tle發揮轉錄抑制功能來說是必需的。
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