轉錄突變 的英文怎麼說

中文拼音 [zhuǎnlùtūbiàn]
轉錄突變 英文
transcription mutation
  • 轉 : 轉構詞成分。
  • 錄 : Ⅰ名1 （用做記載物的名稱） record; register; collection; selections 2 （姓氏） a surname Ⅱ動詞1 （...
  • 突 : Ⅰ動詞1 （猛沖） dash forward; shoot out 2 （高於周圍） protrude; bulgeⅡ副詞（突然） abruptly; sud...
  • 轉錄 : [電學] transcribe; transfer; [聲學] mixing; rerecording; [生物學] transcription; duplicating轉錄...
  • 突變 : 1 （突然急劇的變化） sudden change; change suddenly; transilience; accident; saltation; revulsion...
  1. Clonal analysis in this study on the eye imaginal disc showed that in the oxt mutant clones, the ci expression was completely deleted

    胚胎分析結果表明則t基因的突變會導致wg的轉錄和engrailed基因的表達受抑。
  2. It implies that gene expression in plant cells might have changed under the stimulation of sound wave. thirdly, the cell cycle of protoplast of control group and stimulated group ( stimulating for 9 days ) was estimated by flow cytometer. the results showed that the number of cells of stimulated group decreased in g0 / g1 phase and increased in s phase

    圍繞中心法則分別測定了dna 、 rna和可溶蛋白質的含量，發現聲波刺激組的dna含量變化不明顯，而rna和可溶蛋白質的含量都有所升高，且以刺激9天的實驗組最為突出，表明在強聲波的作用下，有關應力響應的轉錄因子被啟動，轉錄水平提高，從而翻譯合成較多的蛋白質，促進植物的生長發育。
  3. Sometimes we want to stop a gene from expressing its product, because the product is toxic ( such as the mutation that causes huntington ' s disease ), but even then we can probably achieve the desired effect just by putting in a gene, because we can use the amazing phenomenon of rna interference to cause the gene ' s transcript to be destroyed before it is translated

    有時，我們要停止一種基因表達它的產物，因為這種產物有毒性（例如，引起亨廷頓氏舞蹈病的突變） ，但即使在這種情況下，我們也有可能僅僅放進一個基因，來達到想要達到的效果，因為我們可以利用rna干涉的這種令人驚訝現象、在該基因的轉錄物在被翻譯之前就毀壞它。
  4. Abstract : plant responses to salt stress via a complex mechanism, including sensing and transducing the stress signal, activating the transcription factors and the corresponding metabolizing genes. since the whole mechanism is still unclear, this review emphasize the biochemical events during the plant adaptation to salt stress referring to an index of importance : the homeostasis in cytoplasm, the biosynthesis of osmolytes and the transport of water. most of these biochemical events were elucidated by study of halophyte and salt - sensitive mutations, also many important genes involved were cloned and used to generate stress - tolerance phenotypes in transgenic plants. on the other hand, about the molecular mechanism in signal transduction, the research of arabidopsis mutations and yeast functional complementation provided helpful traces but not full pathway

    摘要植物對鹽脅迫的耐受反應是個復雜的過程，在分子水平上它包括對外界鹽信號的感應和傳遞，特異轉錄因子的激活和下游控制生理生化應答的效應基因的表達.在生化應答中，本文著重討論負責維持和重建離子平衡的膜轉運蛋白、滲調劑的生物合成和功能及水分控制.這些生理生化應答最終使得液泡中離子濃度升高和滲調劑在胞質中積累.近年來，通過對各種鹽生植物或鹽敏感突變株的研究，闡明了許多鹽應答的離子轉運途徑、水通道和物種特異的滲調劑代謝途徑，克隆了其相關基因並能在轉基因淡水植物中產生耐鹽表型;另一方面，在擬南芥突變體及利用酵母鹽敏感突變株功能互補篩選得到一些編碼信號傳遞蛋白的基因，這些都有助於闡明植物鹽脅迫應答的分子機制。
  5. Ie protein have multiple functions, such as conversion of the host cell into a metabolically activate states, activation of viral early genes in the early phase, repression of their own transcription. ie 180 proteins can stimulate transcription from both homologous such as the icp4 of hsv ( herpes simplex virus ) and heterologous viral and cellular promoter such as - globe protein

    經分析偽狂犬病病毒立即早期蛋白（ immediate - earlyprotein180 ， ie180 ）的蛋白質結構，發現ie180具有轉錄激活因子的結構特徵，能與類rna聚合酶結合， ie180基因缺失突變體對sv40及cmv啟動子調控作用的研究，是考察ie180能否作為轉錄激活因子應用的關鍵。
  6. By artificially changing a to c at - 137 bp site upstream from transcription start point of cloned promoter, two site - mutation promoters, ipms ( 603 bp ) and ipm1 ( 900 bp ) were created

    通過pcr方法對克隆的兩個啟動子進行定點突變，使轉錄起始位點上游- 137bp處a突變為c ，得到兩個突變啟動子（ ipml 、 ipms ） 。
  7. 2. specific mutation from a to c at - 137 bp site upstream from transcription start point had no effect on the inducibility of the promoter in response to sa and bth. 3

    在轉錄起始點上游137bp定點將a突變為c后，對化學啟動子的化學誘導應答性沒有明顯的影響，但對誘導效應的向上運輸存在一定程度的阻抑作用。
  8. The ie 180 mutant combined with two special protein binding - sites and inhibited the promoter transcription. accidentally in the approach showed that the plasimd pcdna3 show as activator to sv40 and cmv early promoter. the result is acquired by instantaneous transinfect

    這說明不同的ie180突變體，對于sv40啟動于這類在轉錄起始位置一側只有一個「 5 』 atcgt 3 』 」特徵蛋白質結合序列的11類基因啟動于，可分別表現出抑制活性與激活性。
  9. 900 bp promoter - directed gus expression was highly induced by sa and bth, while the 603 bp promoter, whether mutated or not, did not respond to sa and bth induction, which indicated that the element in response to sa and bth lied among 575 ~ 872 bp from transcription start site

    全長900bp啟動子能夠應答sa和bth的誘導，而603bp長的啟動子無論突變與否對sa和bth均無應答，證明sa和bth的應答區域在克隆啟動子的轉錄起始位點上游575 872bp之間。
  10. The plasmids pci - mbl54 containing full length of mutations mbl cdna were propagated hi escherichia coli xl - 1 blue, then the extracted and purified pci - mbl54 were used to transfect dhfr ( - ) chinese - hamster ovary ( cho ) cells. after screeened with g418 and cloned, 4 g418 - resistent clones were randomly selected for detection of mrna expression by rt - pcr and molecular beacons. it was found that all of the 4 positive cell clones expresse mbl analogue as detected in transcription level

    抽提、鑒定、純化重組質粒后，脂質體轉染法將重組質粒導入中國倉鼠卵巢細胞（ cho - dhfr ~ - ）中， g418選擇轉染子並克隆化培養，經rt - pcr和分子燈塔探針雜交鑒定其mrna轉錄，獲得4株穩定表達54位密碼突變型mbl的cho細胞。
  11. 4. the wild tomato and nr mutant fruit discs treated with wound, nacl and peg to detect expression changes of le - acs gene family. the experiment showed that during the ethylene production under stress conditions, the le - acs2 gene expression maintained at a high level, different from system i ethylene production transition to system ii. this suggested that stress conditions changed the regulatory mechanism of le - acs2

    傷、 nacl 、 peg處理普通型番茄和nr突變體番茄的組織圓片研究le - acs基因家族的表達變化，結果表明：在脅迫乙烯生成過程中， le - acs2一直呈高水平表達，不存在如同系統向系統乙烯的轉化中le - acs基因家族的表達過渡，因此，脅迫條件下le - acs2基因的轉錄調控機制發生改變。
  12. These alleles showed wg - like phenotype ( notch et al. ), the germline clone embryo showed cuticle fusion phenotype

    這些突變或是無義突變（ b158和b140 ）或是破壞原初轉錄本剪接的突變（ b173 ） 。
  13. The clpg mutation is a a g substitution 32. 8 kb upstream of gtl2, which was later shown to be the only difference between the callipyge and wild - type chromosome in what is probably a long - range control element ( lrce )

    2002年， freking等人發現了一個位於gtl2基因上游32 . 8kb的a g的突變，這一突變位於一個新發現的轉錄本clpg1內部，它是callipyge羊和正常羊的唯一不同之處。
  14. The comparative analysis of sequences indicated that the sequences of meq in different pathotypes are relatively conserved and the homology of the amino acid sequences is very high. the significant differences include two mutations in both mdv - 1 vaccine strains cvi988 / rispens and 814 strain : the deletion of a proline ( no. l93aa ), and this mutation is just exactly located in a 15 - amino - acid ( eelcaqlcstppppi ) repeat sequence within the c - terminal transactivation domain of meq protein ; and a point mutation with a shift from alanine ( a ) of all virulent strains to serine ( s ) was occurred on the no. 71 aa

    結果發現， mdv不同致病型的meq基因序列相對比較保守，它們相互間核苷酸和氨基酸序列的同源性均很高；但是，與所有七個致瘤性的mdv毒株相比，二個型弱毒疫苗cv1988 rispens株和814株均出現了兩個特徵性的突變：即第194位的p缺失性突變和第71位氨基酸由a變成了s的位點突變；缺失性突變恰恰位於meq基因中轉錄激活域內的一個多脯氨酸的重復序列（ pppp ）之中。
  15. Based on the blast analysis and other studies, osddl mutant was a multi - copy - insertion mutant, and one of the insertion sites was in an nptii like transposase gene, whereas osdd2, a single - copy - insertion mutant was disrupted at a gene encoded wrky transcript factor

    Osdd1突變體可能是多拷貝插入，其中一個插入到nptii轉座酶類似基因。 osdd2突變體為單拷貝、插入到一個wrky類轉錄因子基因5翻譯起始區附近。
  16. The absence of the fmr1 gene product, fragile x mental retardation protein ( fmrp ), is believed to be responsible for the typical physical and mental characteristics of the fragile x syndrome. alleles with between 43 and 200 cgg repeats are called permutation. they are generally unmethylated with normal transcript and protein level, but are extremely unstable during transmission to next generation

    帶有前突變（ n = 43 200 ）的個體其fmr1基因通常不會甲基化，可以正常轉錄和翻譯產生fmrp ，故沒有臨床表型出現，但是，在向下一代傳遞的過程中卻是非常不穩定的，會從前突變擴增成為全突變。
  17. Cat ( chloramphenical acetyl transferase ) elisa assays to identified the function of constructed plasmid. the result indicates mutant p1p2, p1p3p2 and p6p2 repressed to cmv promoter. same as ie promoter two special sequences " atcgt " located at two side of the transcription initial site of promoter

    共轉染hplp細胞，結果表明所有的缺失突變體對cmv啟動子都表現抑制活性，我們發現在ie180和p啟動子的轉錄起始位置兩側同時具有兩個特徵序列（ 5 』 atffit 3 』 ） 。
  18. Nuclear factor - kb ( nf - kb ) is one kind of cell transcription factor that exist in many kinds of cells in nervous system. it is also has great association with the process of neuronal degeneration and apoptosis. from the above we can see that tbi, secondary brain injury, apoptosis and cytokines associated tightly

    細胞核因子b （ nuclearfactor - b ， nf - b ）是一類普遍存在的細胞轉錄因子，功能性nf - b復合物存在於神經系統的各種類型的細胞中，包括神經元、星形膠質細胞、小膠質細胞、少突膠質細胞中，在神經細胞變性和凋亡過程中起十分重要的作用。
  19. Thus, we believe that atmyb103 is the candidate gene for ms 188

    因此，我們推測， ec - 188突變體可能是轉錄因子atmyb103基因發生突變的結果。
  20. Somewhere along the road to malignancy, the same mutant transcription factor that had switched on the genes enabling the tumor cells to divide unchecked had apparently also switched on the genes needed to produce leu - enkephalin

    在發展成為惡性腫瘤的過程中，同樣的突變轉錄因子不僅激活了能夠使癌細胞無限分裂下去的基因，而且同時激活了能產生亮氨酸腦啡肽的基因。
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