酪氨酸磷酸酶 的英文怎麼說

中文拼音 [làoānsuānlīnsuān]
酪氨酸磷酸酶 英文
tyrosine phosphatase
  • 酪 : 1 （用牛、羊、馬的乳汁製成的半凝固的食品） junket 2 （用果子做的糊狀食品） thick fruit juice; fru...
  • 氨 : 名詞[化學] （氮和氫的化合物） ammonia; hydrogen nitride
  • 酸 : 酸構詞成分。
  • 磷 : 名詞[化學] phosphorus （15號元素,符號p）
  • 酶 : 名詞[生物化學] （生物體的細胞產生的有機膠狀物質） enzyme; ferment
  • 磷酸 : [無機化學] orthophosphoric acid; phosphoric acid磷酸胺 [化學] phosphamide; ammonium phosphate; 磷...
  1. Protein tyrosine phosphatases

    蛋白質酪氨酸磷酸酶
  2. Vanadate, a potent ptpase inhibitor, locks adipocyte differentiation at an early stage in the program and leds to the accumulation of p - c - crkii, a phosphotyrosyl protein that is a substrate for ptpase ha2

    研究發現一種強烈的磷酸酯酶抑制劑- -釩酸鈉能夠作用於脂肪細胞的分化早期過程從而抑制其分化，並使一種ptpha2的底物即酪氨酸磷酸化的蛋白質p - c - crkii累積。
  3. The enzyme digest analysis shows that the arm repeats of c - terminal are conceivably conservative domain. in arc1 protein, there are some active sites including n - glycosylation sites, camp - and cgmp - dependent protein kinase phosphorylation sites, protein kinase c phosphorylation sites, casein kinase ii phosphorylation sites, tyrosine kinase phosphorylation sites, n - myristoylation sites, amidation sites and leucine zipper pattern. it probably take part in the signaling process of self - incompatibility

    同時在arc1蛋白質中還發現了拉鏈結構和多個磷酸化位點，包括camp和cgmp依賴的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨酸激酶磷酸化位點、糖基化位點等，拉鏈結構為arc1蛋白之間及與其它蛋白的相互作用提供了可能，而磷酸化位點是arc1參與信號傳導過程所必需的。
  4. Northern blot results show that nos. 66 - 1, 84, 89 - 1, 97, 108, 152, 175 and 233 have stronger signal in sp6 - tester than in sp6 - driver ; and no. 23 has weak signal only in sp6 - tester, nos. 94, 165, 172, 185 and 191 have similar hybridization signals in both sp6 - tester and sp6 - driver ; nos. 4, 17, 18, 28, 6 9, 101, 156 - 1, 157 - 1 and 183 do not reveal hybridization signals in both sp6 - tester and sp6 - driver ; the results of sequencing and blastn and blastx on ncbi indicate that no. 23 cdna ( 846bp ) has significant alignments with nicotiana tabacum mrna for elicitor inducible beta - 1 - glucanase nt - sube76, and arabidopsis thaliana clone 7119 for glycosyl hydrolase family 17 ( protein id : at5g55180. 1, supported by cdna : 7119, supported by cdna : gi _ l 87001 54 ) and arabidopsis thaliana beta - 1 - glucanase - like protein ( gi _ 2 1594590 ) ; no. 84 cdna ( 560bp ) has significant alignment with lotus corniculatus aspartate aminotransferase mrna ( complete cds length = 1685, gi | 2605931 | gb | af029898. 1 | af029898 ) for aspartate aminotransferase ; no. 89 - 1 cdna has significant alignment with arabidopsis tha

    與同源性最高的擬南芥類似晚期胚胎發生高豐度蛋白比較，二者都具有lea 2結構域、保守分泌蛋白cog5608結構域和低復雜度區，都具有pkc磷酸化位點、酪蛋白激酶磷酸化位點、 n十四酞化位點和酚胺化位點，所不同的是： （ ）在結構功能域上， 152全長cdna編碼的蛋白質序列中多了1個lea 2結構域、 l個保守分泌蛋白cog5608結構域和1個低復雜度區； （ 2 ）在功能位點上， 152全長cdna編碼的蛋白質具有酪氨酸硫酸化位點、多了l個酪氨酸激酶磷酸化位點和1個可能的天冬氨酸富集區，但沒有n糖基化位點； （ 3 ）擬南芥類似晚期胚胎發生高豐度蛋白的lea 2結構域具有顯著性（ e
  5. The cyst cells enclosing spermatomeres maybe synthesize a kind of scf - like protein, which can recognize specially the c - kit receptor on the cellular membrane of spermatomeres. then c - kit is activated, dimerizing and autophosphorylating. at the same time, the tyrosine kinase domain of c - kit is activized, which phosphorylates the proteins that have sh2 domain

    精母細胞周圍的囊細胞可能合成scf樣蛋白，特異地識別精母細胞膜上的c - kit受體，並刺激c - kit發生二聚化、自體磷酸化，激活胞內酪氨酸激酶活性，活化具有「 sh _ 2結構域」的靶蛋白，可能通過一系列信號級聯，最終激活與減數分裂的相關蛋白或基因。
  6. Focal adhesion kinase tyrosine phosphorylation promotes rat hepatic fibrogenesis and its possible mechanism

    黏著斑激酶酪氨酸磷酸化促大鼠肝纖維化形成及其可能機制
  7. It is divided to extracellular and intracellular part by transmembrane domain. there are 13 n - glycosylation sites, 20 protein kinase c phosphorylation sites, 28 casein kinase ii phosphorylation sites, 4 tyrosine kinase phosphorylation sites and 15 n - myristoylation sites in the extracellular part of bt - r3 protein. an integrin recognition sequences rod lies in intracellular part of bt - r3 protein

    跨膜區域（ tmd ）將它分為胞內和胞外兩個部分，它的胞外有13個潛在的糖基化位點， 20個蛋白激酶c的磷酸化位點， 28個酪蛋白激酶的磷酸化位點， 4個酪氨酸酶的磷酸化位點， 15個豆蔻（十四烷基）酰化位點；它的胞內有1個整合蛋白（ integrin ）識別位點。
  8. Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

    Huangya14 ）為材料分離克隆到一個細胞色素p450基因，命名為bccyp86mf5 ， cdna全長1854bp ，含1575bp的完整開放閱讀框，編碼524個氨基酸，其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ；堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ；二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域，半胱氨酸亞鐵血紅素配體信號區等， -螺旋和-折疊分別佔47 . 7 、 45 . 0 ；與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ，與擬南芥cyp86c4的達到85 . 9 。
  9. Ngf binding to trka receptors results in receptor dimerization and kinase activation. recent evidence supports that not all extracellular subdomains are responsible for receptor activation. structure based drug design for neurotrophic agonists with small molecular weight relies on knowledge of the interaction of neurotrophin with their receptors

    Trka在ngf作用下發生二聚化，使胞內域中酪氨酸激酶區激活，從而使trka中酪氨酸自磷酸化，並進一步激活胞內信號轉導通路，從而實現神經營養信號傳遞。
  10. Many cell signal transduction pathways have been discovered in the regulation of apoptotic induction and reduction. mito - gen - activated protein kinase ( mapk ) is a group of particular ser / thr protein kinases which are activated when its conservative thr and tyr residues are both phosphorylated by upstream mapk kinases

    絲裂原活化蛋白激酶（ mapk ）是一群特殊的絲蘇氨酸蛋白激酶，它通過其上游mapkk使其保守的蘇氨酸和酪氨酸殘基雙磷酸化而活化，活化的mapk可轉移到核內，參與基因表達調控。
  11. Both spla 2 and ceramidehave been shown to inhibit bradykinin -, and pma - induced phospholipase d activation. these results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways. in addition, we also found that spla can 2 down regulate theepidermal growth factor ( egf ) receptor activation

    此外，我們還發現分泌型磷脂酶a能下調表皮生長因子受體的活化，它能明顯的抑製表皮生長因子誘導2的受體自身磷酸化，並抑製表皮生長因子誘導的磷脂酶d活性和磷脂酶c - g的1酪氨酸磷酸化。
  12. Sh2 domain can specifically recognize phosphated tyrosine residue, and mediate receptor tyrosine protein kinase signal transduction

    Shz結構域可以特異性識別磷酸化酪氨酸短序列，介導受體酪氨酸蛋白激酶信號轉? 2 ?導途徑。
  13. The key mechanisms involved are inhibition of protein - phosphotyrosine phosphatases and activation of nonreceptor protein - tyrosine kinases, in an insulin - receptor tyrosine kinase independent fashion

    釩在生物體內發揮作用的主要機制是通過蛋白磷酸酪氨酸磷酸酯酶的抑制和非受體蛋白酪氨酸的激活一種與胰島素受體完全不同的途徑發揮作用的。
  14. It has been demonstrated that kvl. 2, an isoform of delayed - rectifier potassium channel, is up - regulated in the ischemic neurons. besides, the activity of kvl. 2 is tyrosine phosphorylation dependent, phosphorylation of the tyrosine residue in the amino terminus of the channel by tyrosine kinases suppresses the channel current. therefore, we hypothesize that vegf could enhance the phosphorylation of kvl. 2, which results in an inhibition of / k

    在介導i _ k的鉀通道家族中， kv1 . 2是其中的一個亞型，研究報道它在缺血神經元中的表達是增高的；此外，它的活性與其酪氨酸磷酸化水平相關，在其氨基末端的酪氨酸殘基經酪氨酸激酶磷酸化后可顯著降低其介導的電流的幅度。
  15. A search by profscan program showed that some predicted modification sites including four protein kinase c phosphorylation sites, three casein kinase ii phosphorylation sites and so on distributed over the protein sequence of trptl

    此外，在整個氨基酸序列中，還有4個蛋白激酶c磷酸化位點、 3個酪氨酸激酶位點等不同的修飾位點。
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