顱脊柱裂畸形 的英文怎麼說
中文拼音 [lújǐzhùlièjīxíng]
顱脊柱裂畸形
英文
craniorachischisis- 顱 : 名詞[生理學] （頭的上部） cranium; skull
- 脊 : 脊同 「脊」
- 裂 : 裂動詞[方言] （東西的兩部分向兩旁分開） open
- 畸 : Ⅰ形容詞1 （偏） lopsided; unbalanced2 （不正常的; 不規則的）irregular; abnormalⅡ名詞[書面語] （零...
- 脊柱 : spinal column; vertebral column; backbone; spine; columnar vertebralis （俗稱「脊梁骨」）
- 畸形 : deformity; dysmorphia; dysmorphosis; malformation; dysgenesis; monstrosity; monstrousness; un sha...
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The protein nucleic acid complexes were identified by autoradiography for 48 h. the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2, with lonm tcdd and with both lonm tcdd and 1 jxm e2, individually ; the cat protein was examined by cat - els a. results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect. the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra, whereas the cell proliferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨骼致畸作用，骨骼發育畸形包括:內翻足、脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高（ 10一15林擴kg ） ，致畸率明顯上升（ 14 . 7 %一24 . 6 % ） ; tcdd和ra聯合用藥可以增強對大鼠骨骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用，對igfbp一6基因有負性調節作用， tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。
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