cell-attachment protein 中文意思是什麼

cell-attachment protein 解釋
細胞附著蛋白
  • cell : n 1 小室，單室；隔間，艙；〈詩〉茅舍；（單個的）蜂窩，蜂房。2 〈詩〉墓穴，墓。3 （大修道院附屬的...
  • attachment : n. 1. 附著，附著物；附屬物，附件。2. 愛慕，依戀；依附 （for; to）。3. 【法律】逮捕；扣押（人，財產）。4. 扣押證。
  • protein : n. 【化學】朊，蛋白（質）。
  1. Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities

    因此將這些蛋白包被、固定到材料表面，觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節，並從以下方面進行探討： （ 1 ）採用不同原代細胞分離方法，研究其對mscs細胞的生物學特性影響。 （ 2 ）檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 （ 3 ）分別採用型膠原及纖維粘連蛋白（ fibronectin ， fn ）包被聚乙醇酸-乳酸共聚物（ poly （ 1actide - co - glycolide ） ， plga ）膜及多孔塊型plga材料，觀察細胞在單層或三維培養狀態下，型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。
  2. The results showed that it was fibronectin which increased cell attachment so that cells could not be detached, and albumin did n ' t influent the cell detachment, but influented the adsorption of fibronectin, surface analysis demonstrated that the coated protein would not affact the wettability of azphpia. the function of azphpia could not resist the function of fibronectin so that the application of thermoresponsine biomaterial in serum cell culture system is limited. in section two, it was also first time to systhesis phycocyanin ( pc ) anti - tumor polymer

    在第三章中，首次成功將具有抗腫瘤活性的藻藍蛋白、藻總蛋白、硒化藻藍蛋白，通過光化學固定法，共價接枝到聚苯乙烯膜上，製成新的光固定化抑癌生物材料，接著華南師范大學博土學位論文中文摘要研究藻藍蛋白光固定化聚苯乙烯膜對肝癌細胞7402生長的體外抑制作用及硒和螺旋藻中其它蛋白質對藻藍蛋白活性的影響。
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