checkpoint arrest 中文意思是什麼
checkpoint arrest
解釋
關卡滯留- checkpoint : 復習要點
- arrest : vt. 1. 逮捕，拘捕，扣留。2. 止住，阻止，抑制。3. 吸引（注意）。n. 1. 停止，阻止，抑制；制動（裝置）。2. 逮捕，拘留，收押。
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Rapid responses occured when cells were exposed to genotoxic stresses : one is initiating dna damage checkpoint that leads to arrest in gl, in order to provide the cell with sufficient time to repair damaged dna, or leads to arrest in g2, in order to avoid defective chromosome happening mitosis. on the other hand, if damage to the genome is excessive, the cells initiating apoptosis, when damages cannot be repaired
這是因為細胞在受到諸如電離輻射等基因毒應激損傷時，細胞最先作出的細胞學反應：一，起始dnadamagecheckpoint使細胞周期阻滯（ arrest ）在g1期，贏得時間識別與修復損傷，避免損傷的dna進行錯誤的復制，或和阻滯在g2期，避免缺陷的染色體進一步分裂；二，損傷嚴重而修復無望啟動細胞死亡程序，清除那些帶有病變傾向的細胞危害機體。
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