defective dna 中文意思是什麼
defective dna
解釋
缺損dna-
Over - expression of yggg retarded the cell cycle, on the point after dna partition, resulting in accumulation of diploid as bacteria stop division and sequentially went to death. this appearance is similar to that of the era mutants, including the partially defective in era gtpase activity or the reduced in the synthesis of wild - type era which bacteria become arrested in the cycle at the predivisional two - cell stage
在熒光顯微鏡下細菌形態的變化，以及dapi染色和透射電子顯微鏡觀察， yggg的表達與era突變（使era功能降低時）對細菌分裂的影響有類似之處，即細菌dna合成，子代dna分離后；分裂停滯，形成細菌繁殖受阻時， 2 - 4倍體的出現。 -
Rapid responses occured when cells were exposed to genotoxic stresses : one is initiating dna damage checkpoint that leads to arrest in gl, in order to provide the cell with sufficient time to repair damaged dna, or leads to arrest in g2, in order to avoid defective chromosome happening mitosis. on the other hand, if damage to the genome is excessive, the cells initiating apoptosis, when damages cannot be repaired
這是因為細胞在受到諸如電離輻射等基因毒應激損傷時，細胞最先作出的細胞學反應：一，起始dnadamagecheckpoint使細胞周期阻滯（ arrest ）在g1期，贏得時間識別與修復損傷，避免損傷的dna進行錯誤的復制，或和阻滯在g2期，避免缺陷的染色體進一步分裂；二，損傷嚴重而修復無望啟動細胞死亡程序，清除那些帶有病變傾向的細胞危害機體。
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