double-strand break 中文意思是什麼
double-strand break
解釋
雙鏈斷裂-
Recently, a new gene dr0167 ( pprl or irre ) that serves as a general switch for downstream dna repair and protection pathways via its regulatory function on the gene expression of reca, ppra was discoveried. expression of d. radiodurans pprl also promotes dna repair and protection pathways and enhances the radioresistance of e. coli. this finding provides a new clue to understand the mechanism of dna repair, especially double strand break ( dsb ) repair
最近我們實驗室在耐輻射球菌電離輻射敏感株中鑒定了一個與電離輻射抗性相關的基因ppri ，該基因可能通過調控dr細菌reca 、 ppra等基因的表達加速對電離輻射引起的dna損傷修復，而在大腸桿菌中表達ppri基因能促進reca 、 soda等表達水平顯著提高，使其抗輻射和抗氧化能力明顯增強，這將為我們理解其特殊抗性機制，特別是雙鏈斷裂修復提供新的線索。 -
The dna double strand break ( dsb ) can be rejoined by at least two discrete pathways, i. e., the homologous recombination and the nonhomologous end - joining. at least 10 genes were found involved in nhej
Rad18是一種單鏈dna結合蛋白，具有許多泛素系統e3所有的典型ring結構，與rad6 （ ubc2 ）形成結合緊密的異二聚體。
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