epitope library 中文意思是什麼
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The 7mer peptide and 12 mer peptide selected from the peptide library elicited strong anti - vegf antibody immuno - reaction in mice. dna sequenseing showed that gwyydal and vasavfysalve mimic the discontinuous epitope of vegf by the 14 - 17, 21 and 21 25 amino acid residues respectively
兩者可能分別模擬了vegf分子的21 、 25位氨基酸和14 、 17 、 21位氨基酸通過折疊后在三級結構水平上形成的結合位點和vegf競爭結合受體。 -
In this study we screen the phage - epitope library in attempt to predict the receptor recognition site on vegf, identify peptide able to block the interaction of vegf - kdr and find a potent vaccine against tumor angiogenesis by targeting vegf
[方法]以兩個具有中和vegf活性的抗- vegf單克隆抗體jh121 、 vg189為目標，分別對噬菌體隨機7肽、 12肽庫進行篩選。 -
Identification of the epitope of prrsv n protein monoclonal antibody with phage displayed random peptide library
蛋白單克隆抗體識別的表位 -
Identification of epitope recognized by monoclonal antibody with phage - displayed random peptide library
噬菌體隨機肽庫在確定單抗識別表位中的應用 -
The mechanism of ki 11 ing the schistosomulae in vitro depending on the specific ige antibody were observed. the distribution of the protein encoded by the cloned gene was determined by immuno - electromicroscopy with protein a - colloidal gold. in order to further analyse the epitope features of the protein relevant to the specific ige antibody, the phage display library of random peptides was screened by pooled sera with the specific ige antibody
藉助現行生物信息學分析手段，通過網際網路進入genbank數據庫，對sj43b與已知序列進行同源性比對，應用dnatoois軟體對其編碼蛋白序列的氨基酸紐成、親水性、抗原性和可及性進行分析，並在blastp程序下在genbank蛋白數據庫中對sj43b編碼3人卞醫科大學博士學杠論文蛋白進行同源性檢索。 -
2 specific epitope analysis in m3m4 loop target to determine the b cell epitope of a monoclonal antibody against the m3 - m4 loop of nmdar1, a random phage displayed dodecapeptide library was screened with the monoclonal antibody mab363 against the m3m4 loop of nmdar1. after four rounds of biopanning, the peptide sequences of positive phage clones were determined and analyzed by dna sequencing
流式細胞儀測定脾細胞cd4 + 、 cds寸淋巴細胞亞群，間接elisa測定血清thl細胞因子幾一2 、 tn下一a和n一y ， th一2細胞因子幾一4 、 il巧和幾一6的水平，同時檢測特異性抗體產生情況。 -
After 3 rounds of screening, 10 of 20 clones were identified as positive clones and all the 10 phage clones sharing the same amino acid sequence : ehmaltypfrpp, and these positive 12mer phage clone peptide can bind with tnfa specifically. the results suggests that this method is very specific and simple for screening of binding epitope to small peptide molecule from phage display peptide library
在以噬菌體環七肽tnfa模擬肽克隆刁k naqsoc ）為靶對噬菌體隨機十二肽庫進行h輪篩選后，挑取20個克隆，經elisa鑒定有10個克隆均與t 』 nfa結合，測序結果顯示它們均為同一氨基酸序列： ehmaltypfrpp 。
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