gene activation 中文意思是什麼

gene activation 解釋
基因活化
  • gene : n. 【生物學】基因。 dominant gene顯性基因。
  1. Catabolite gene activation protein

    降解物基因活化蛋白
  2. 13 chatterjee - kishore m, wright k l, ting j p, stark g r. how stat1 mediates constitutive gene expression : a complex of unphosphorylated stat1 and irf1 supports transcription of the lmp2 gene. embo j., 2000, 19 : 4111 - 4122. 14 mahboubi k, pober j s. activation of signal transducer and activator of transcription 1 stat1 is not sufficient for the induction of stat1 - dependent genes in endothelial cells

    例如, jak - stat中, socs1 ppn以及stat1蛋白對于系統輸出的影響相對其他蛋白來說要明顯的多,這三個蛋白主要控制著jak - stat信號通路的「信號幅度」和響應強度response magnitude ,最大響應值。
  3. The aglycone, steviol, exhibited greater acute toxicity than stevioside in hamsters but not in rats. steviol was clearly genotoxic after metabolic activation, inducing forward mutations in bacteria and gene mutations and chromosomal aberrations in lung fibroblasts of chinese hamsters

    甜菊醇經過代謝活化后,基因毒性明顯,可引致細菌產生正向突變,以及使中國倉鼠的肺纖維原細胞產生基因突變和染色體變異。
  4. Epigenetic modification of the genome ensures proper gene activation during development and involves : genome methylation changes ; the assembly of histon and histone variants into nucleosomes and remodeling of other chromatin - associated proteins such as linker histones, polycomb group, nuclear scaffold protein, and transcription factors

    這些染色質的再程序化包括dna的甲基化和核小體組蛋白的乙酰化等。組蛋白乙酰化在染色質結構調節、 dna復制、基因轉錄、細胞分化及癌細胞發育都有研究,但在克隆動物中卻是一個有待深入探索的領域。
  5. It has been known for some time that the acetylation of n - termini of core histones in nucleosome is associated with gene activation

    人們很早就注意到,真核細胞中核小體核心組蛋白n -端尾部的乙酰化水平與基因活化密切相關。
  6. However, it is difficult to relate the histone acetylation level with the gene expression level. we indicate, although histone acetylation acts to enhance the access of transcription - associated protein to dna, the activation of gene expression only need containing some acetylation level, but the hyperacetylation and underacetylation would effect the gene expression, so as to the abnormal development

    而在克隆牛中組蛋白乙酰化水平雖然有所降低,但如果這種降低仍然為基因的表達提供了足夠的基礎,這就對基因的正常表達造不成很大影響;但如果組蛋白乙酰化水平過高或過低,可能要影響到其他因子的作用,從而影響了基因表達的調節,最終導致生物個體發育異常。
  7. The gpa1 gene was obtained via pcr amplification and was cloned in the two - hybrid dna binding domain vector pgbkt7 the combinant plasmid was designated as pgbkt7 - ga. - galactosidase assay indicated that got did not have the property of self - activation. after pgbkt7 - ga was transformed to yeast pj69 - 4a, we transformed arabidopsis vegetative tissue two - hybrid cdna library plasmids to yeast pj69 - 4a containing pgbkt7 - ga

    通過pcr擴增得到gpa1基因並將其克隆到雙雜交dna結合域載體pgbkt7中,得到的重組質粒命名為pgbkt7 - g , ?半乳糖苷酶活性鑒定表明g不具有自激活特性,將其轉化到酵母菌pj69 - 4a中,再以此為受體菌轉化擬南芥綠色營養組織cdna文庫質粒。
  8. Analysis of transcriptional activation abilities of three gmdreb proteins in yeast indicated that gmdreba and gmdrebb could activate the expression of a reporter gene, whereas gmdrebc could not

    轉錄激活活性分析表明, gmdreba和gmdrebb蛋白能夠激活下游報告基因的表達,而gmdrebc不能,說明gmdrebc蛋白不具有轉錄激活活性。
  9. Exposure to genotoxic agents would trigger a series of comprehensive and complex responses in cells to counteract the abnormal conditions, which include the rapid activation of signal transduction pathways independent of the nuclear damage signal and late alteration of gene expression

    自環境毒物接觸細胞開始,細胞就發生了一系列廣泛和復雜的應答反應以應對此不良環境。其中包括了即刻發生的並不依賴于核損傷信號的信號轉導通路的激活和較遲發生的基因表達的改變。
  10. This kind of mutation may be not only being triggered by the signals originated from dna damage, but also by the signals of extra - nuclear origin through the epigenetic pathway including the activation of various signal transduction pathways and alterations of gene expressions

    這種突變除了可能由dna損傷觸發的途徑外,已證明還有非核起源的信號觸發的外遺傳( epigenetic )途徑介入,激活細胞信號轉導通路,引起一系列基因表達的改變而最終導致突變的形成。
  11. These findings suggest that c. chinensis extract may interact with cell surface membranes in a different way from ngf, and indirectly activate ngf receptor. consequently, c. chinensis extract shares the common pathway induced by ngf, leading to activation of specific gene required for the differentiation process

    這說明菟絲子提取物可能通過一種不同於ngf的方式與pc12細胞作用,間接地活化ngf受體;隨后通過與ngf相同的方式激活誘導細胞分化的相關基因,從而誘導pc12細胞分化。
  12. No touches upon multiple aspects of intracellular signaling pathways such as gene activation, protein expression and activity regulation of enzymes

    No參與了跨膜信號轉導的多個層面,如基因活化、蛋白質表達和酶活性的調節。
  13. They are involved in the activation of the rd29a gene in response to dehydration, high - salt, and low - temperature stress. the two transcription factors have no significant amino acid sequence identity. however, both the dreb1a and dreb2a proteins contain a typical erebp / ap2 binding motif

    Dreb1蛋白和dreb2蛋白之間,在整體的氨基酸序列上沒有同源性,但這兩個轉錄因子都含有一個十分保守的erebp / ap2結構域,屬于erebp / ap2類蛋白家族。
  14. The well microbial - stimulation, microbial dewaxing, wax control and using microbial for water blockoff and profile control are analyzed, including gene tracking detection and performance analysis in field test of indigenous fungus activation

    通過扶余油田單井微生物吞吐、微生物清防蠟、微生物堵水調剖以及激活本源菌礦場試驗的基因跟蹤檢測和動態分析,分析了影響礦場試驗增產效果的主要因素。
  15. Mature embryo - derived calli of japonica rice ( oryza sativa l. ) cultivars nipponbare were transformed using agrobacterium tumefaciens strain agl1 carrying a binary vector pcas04 harboring the marker gene, neomycin phosphotransferase gene ( nptii ), driven by a promoter from the ubiquitin gene in maize, a promoterless p - glucuronidase gene near to the left border of t - dna for trapping gene and a strong promoter, rice actin - gb promoter, near to the right border of t - dna as activation tagging. in this system, co - cultivation was simplified, special selection stages and pre - regeneration stage were omitted, the whole process was almost under continuous light at 30 ? except co - cultivation and transgenic plants began to generate only after 7 weeks calli were induced

    在一步轉化系統中,光照高溫條件下培養的水稻愈傷組織從誘導開始經過4周時間就可以達到轉化實驗的要求,並且簡化、優化了整個共培養過程,省去了一篩、二篩和預分化步驟,只用7周的時間就可以初步得到再生轉化植株;共191塊愈傷組織得到125塊抗性愈傷組織,轉化頻率達到65 . 4 ,最後共得到99棵獨立來源的再生植株,抗性愈傷組織再生頻率達到79 . 2 。
  16. However, the exact mechanisms of transcriptional activation of the badh gene leading up to such activation events remain poorly understood

    Badh基因受脅迫誘導表達,但是對它轉錄調控的分子機制還不清楚。
  17. This data indicated the expression of baf complex and nf1 / ctf is closely related to cell activation and gene transcription activities

    以上實驗表明, baf復合物和轉錄因子nf1 ctf在細胞中的表達是與細胞活化和基因轉錄活動密切相關的。
  18. 2, by using the above system, we demonstrated that yelp3, yhelp3 and help3 were able to completely, dramatically and partially complement the growth defects and the slow activation of pho5 and ssa3 gene caused by the depletion of yelp3, respectively, while yhelpbhat " whose catalytic domain was partially de

    7 、 h4ks一r對i功五藝p3 、力幾p3與少凡p3功能的影響大於h3k14一r ,表明體內組蛋白不同位點的乙酞化修飾對基因表達有不同的影響。
  19. However, dna damage has been ruled out as the prerequisite for alkylating agents - induced mutagenesis. for example, somatic hypermutation, which occurred around the variable region in the immunoglobin gene of b cells, is driven by antigen activation not by dna damage and is considered a kind of active mutation

    但是dna損傷並不是引起突變的必要條件,一個典型的例子就是發生在b淋巴細胞的免疫球蛋白( ig )可變區基因上的「體細胞超突變( somatichyermutation ) 」 ,是由表面抗原受體而不是dna損傷驅動的主動突變。
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